Development Level

Tbio 236 | 11,445
Tdark 29 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 22 | 979
preweaning lethality, incomple... 15 | 499
decreased body weight 9 | 161
abnormal behavior 8 | 298
embryonic lethality prior to t... 8 | 278
abnormal bone structure 6 | 187
abnormal embryo size 6 | 220
increased or absent threshold ... 6 | 101
abnormal sleep behavior 5 | 70
decreased circulating choleste... 5 | 93
decreased total body fat amoun... 5 | 207
hyperactivity 5 | 148
abnormal behavioral response t... 4 | 66
abnormal coat-hair pigmentatio... 4 | 64
decreased circulating amylase ... 4 | 28
decreased circulating total pr... 4 | 49
decreased lean body mass 4 | 135
embryonic lethality prior to o... 4 | 239
increased lean body mass 4 | 172
abnormal bone mineralization 3 | 38
abnormal coat appearance 3 | 31
corneal opacity 3 | 32
decreased blood urea nitrogen ... 3 | 51
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating fructosa... 3 | 30
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased circulating iron lev... 3 | 32
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
embryonic growth retardation 3 | 106
increased body length 3 | 32
increased body weight 3 | 25
increased circulating alkaline... 3 | 122
increased circulating chloride... 3 | 41
increased circulating phosphat... 3 | 26
increased circulating sodium l... 3 | 71
increased heart weight 3 | 62
increased total body fat amoun... 3 | 134
increased vertical activity 3 | 24
prenatal lethality prior to he... 3 | 87
abnormal cornea morphology 2 | 31
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal spleen morphology 2 | 55
abnormal vocalization 2 | 21
absent pinna reflex 2 | 23
cardiovascular system phenotyp... 2 | 36
convulsive seizures 2 | 13
decreased body length 2 | 101
decreased bone mineral content 2 | 151
decreased caudal vertebrae num... 2 | 53
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased grip strength 2 | 116
decreased hemoglobin content 2 | 68
decreased mean corpuscular vol... 2 | 79
decreased prepulse inhibition 2 | 82
enlarged heart 2 | 210
fused cornea and lens 2 | 5
impaired righting response 2 | 26
increased blood urea nitrogen ... 2 | 48
increased circulating iron lev... 2 | 30
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
increased monocyte cell number 2 | 63
increased red blood cell distr... 2 | 34
persistence of hyaloid vascula... 2 | 33
prolonged ST segment 2 | 36
abnormal embryo turning 1 | 31
abnormal lens morphology 1 | 81
abnormal retinal inner nuclear... 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
decreased T cell number 1 | 15
decreased circulating calcium ... 1 | 36
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased bone mineral density 1 | 72
increased circulating amylase ... 1 | 25
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
long tibia 1 | 25
small thymus 1 | 16
thin ventricular wall 1 | 24
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 210 | 11,493
ovarian cancer 147 | 8,520
osteosarcoma 134 | 7,950
glioblastoma 124 | 5,792
medulloblastoma, large-cell 122 | 6,241
psoriasis 118 | 6,694
atypical teratoid / rhabdoid tumor 110 | 5,112
ependymoma 91 | 4,679
Breast cancer 89 | 3,578
Astrocytoma, Pilocytic 79 | 3,081
adult high grade glioma 79 | 3,801
Kidney cancer 78 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 78 | 2,955
pancreatic cancer 78 | 2,398
intraductal papillary-mucinous carcinoma (IPMC) 76 | 2,989
primitive neuroectodermal tumor 76 | 3,035
lung cancer 73 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 72 | 3,291
group 3 medulloblastoma 71 | 4,104
lung carcinoma 70 | 2,843
invasive ductal carcinoma 68 | 2,951
non-small cell lung cancer 63 | 2,890
oligodendroglioma 63 | 2,850
lung adenocarcinoma 60 | 2,716
malignant mesothelioma 60 | 3,232
subependymal giant cell astrocytoma 57 | 2,287
astrocytic glioma 50 | 2,597
acute quadriplegic myopathy 44 | 1,158
colon cancer 43 | 1,478
ductal carcinoma in situ 43 | 1,745
interstitial cystitis 42 | 2,312
ulcerative colitis 42 | 1,819
Duchenne muscular dystrophy 41 | 601
spina bifida 41 | 1,074
breast carcinoma 40 | 1,638
juvenile dermatomyositis 40 | 1,187
tuberculosis 40 | 2,010
primary pancreatic ductal adenocarcinoma 39 | 1,109
group 4 medulloblastoma 38 | 1,855
cystic fibrosis 37 | 1,696
adrenocortical carcinoma 36 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 36 | 1,962
Pick disease 34 | 1,894
pituitary cancer 33 | 1,972
Autosomal recessive predisposition 32 | 1,442
Liver cancer 32 | 604
autosomal dominant Emery-Dreifuss muscular dystrophy 32 | 510
astrocytoma 31 | 1,146
diabetes mellitus 31 | 1,728
Cancer 29 | 2,499
Liver Cirrhosis, Experimental 26 | 769
Melanoma 26 | 711
Rheumatoid arthritis 26 | 1,191
pediatric high grade glioma 26 | 1,064
gastric carcinoma 24 | 807
dermatomyositis 23 | 966
Schizophrenia 22 | 1,160
cutaneous lupus erythematosus 22 | 1,057
Skin cancer 21 | 469
esophageal adenocarcinoma 20 | 737
nasopharyngeal carcinoma 20 | 1,058
Waldenstrons macroglobulinemia 19 | 765
Endometrial cancer 18 | 311
aldosterone-producing adenoma 18 | 665
progressive supranuclear palsy 18 | 676
Atopic dermatitis 17 | 952
medulloblastoma 17 | 720
Cardiomyopathy 16 | 116
Down syndrome 16 | 499
primary Sjogren syndrome 16 | 735
Amyotrophic lateral sclerosis 15 | 451
Intellectual disability 15 | 1,016
Multiple myeloma 15 | 1,332
active ulcerative colitis 15 | 764
pancreatic carcinoma 15 | 562
Myopathy 14 | 185
Nonsyndromic deafness 14 | 142
active Crohn's disease 14 | 922
acute myeloid leukemia 14 | 783
hereditary spastic paraplegia 14 | 318
Bipolar Disorder 13 | 666
Dilated cardiomyopathy 13 | 56
Distal arthrogryposis 13 | 42
Becker muscular dystrophy 12 | 191
Cardiomyopathy, Dilated 12 | 83
Hypertrophic Cardiomyopathy 12 | 117
Wiskott-Aldrich syndrome 12 | 30
fibroadenoma 12 | 559
Familial isolated dilated cardiomyopathy 11 | 41
LEFT VENTRICULAR NONCOMPACTION 10 11 | 40
LEFT VENTRICULAR NONCOMPACTION 8 11 | 40
mucosa-associated lymphoid tissue lymphoma 11 | 484
Acquired scoliosis 10 | 281
Alzheimer's disease 10 | 658
Curvature of spine 10 | 282
Osteoporosis 10 | 363
Short stature 10 | 531
chronic rhinosinusitis 10 | 512
hepatocellular carcinoma 10 | 547
sonic hedgehog group medulloblastoma 10 | 467

Tissue

Endocrine System 267 | 18,159
Skin and soft tissues 265 | 17,230
Male tissues 262 | 17,142
Digestive Tract 260 | 17,369
Blood and immune system 259 | 16,909
Female tissues 258 | 17,400
Liver and Pancreas 257 | 16,750
Urinary Tract 255 | 16,678
Nervous System 252 | 16,725
Cardiovascular System 247 | 15,192
Respiratory system 246 | 16,393

Target Family

Non-IDG 243 | 12,091
Enzyme 22 | 4,145
Kinase 6 | 634
Epigenetic 1 | 242

UniProt Keyword

Actin-binding 272 | 272
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Unconventional myosin-XV MYO15A Tbio Non-IDG -1.64094 42.8 15
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
GAS2-like protein 3 GAS2L3 Tbio Non-IDG -0.65733 5.79 78
Protein Shroom2 SHROOM2 Tbio Non-IDG -1.07032 11.9 112
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myosin-4 MYH4 Tbio Non-IDG -1.81214 51.8 52
Kelch-like protein 5 KLHL5 Tdark Non-IDG 0.04 0.81 49
FH1/FH2 domain-containing protein 1 FHOD1 Tbio Non-IDG -1.49217 38.9 120