Development Level

Tbio 69 | 11,445
Tchem 11 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

IMPC Phenotype

increased startle reflex 5 | 112
abnormal embryo size 3 | 220
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
impaired righting response 2 | 26
increased heart weight 2 | 62
increased neutrophil cell numb... 2 | 46
abnormal body wall morphology 1 | 9
abnormal embryo development 1 | 7
abnormal eyelid fusion 1 | 3
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal kidney morphology 1 | 65
abnormal limb morphology 1 | 13
abnormal pericardium morpholog... 1 | 26
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
hyperactivity 1 | 148
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased lymphocyte cell numb... 1 | 32
microphthalmia 1 | 26
polycystic kidney 1 | 15
polydactyly 1 | 7
protruding tongue 1 | 3
short tibia 1 | 97
vertebral fusion 1 | 23

Disease

Carcinoma 57 | 11,493
ovarian cancer 51 | 8,520
osteosarcoma 50 | 7,950
psoriasis 41 | 6,694
Cancer 38 | 2,499
medulloblastoma, large-cell 38 | 6,241
glioblastoma 36 | 5,792
lung cancer 31 | 4,740
atypical teratoid / rhabdoid tumor 28 | 5,112
pancreatic cancer 23 | 2,398
Breast cancer 22 | 3,578
group 3 medulloblastoma 21 | 4,104
lung adenocarcinoma 21 | 2,716
adult high grade glioma 20 | 3,801
ependymoma 19 | 4,679
invasive ductal carcinoma 19 | 2,951
Multiple myeloma 18 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
non-small cell lung cancer 18 | 2,890
colon cancer 17 | 1,478
diabetes mellitus 16 | 1,728
subependymal giant cell astrocytoma 16 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
lung carcinoma 15 | 2,843
malignant mesothelioma 15 | 3,232
Kidney cancer 14 | 2,613
Waldenstrons macroglobulinemia 14 | 765
breast carcinoma 14 | 1,638
Astrocytoma, Pilocytic 13 | 3,081
astrocytoma 13 | 1,146
oligodendroglioma 13 | 2,850
group 4 medulloblastoma 12 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
pediatric high grade glioma 12 | 1,064
primary pancreatic ductal adenocarcinoma 12 | 1,109
primitive neuroectodermal tumor 12 | 3,035
interstitial cystitis 11 | 2,312
Intellectual disability 10 | 1,016
cystic fibrosis 10 | 1,696
dermatomyositis 10 | 966
pituitary cancer 10 | 1,972
acute quadriplegic myopathy 9 | 1,158
ductal carcinoma in situ 9 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
juvenile dermatomyositis 9 | 1,187
tuberculosis 9 | 2,010
ulcerative colitis 9 | 1,819
Pick disease 8 | 1,894
Vascular disease 8 | 319
astrocytic glioma 8 | 2,597
cutaneous lupus erythematosus 8 | 1,057
pancreatic carcinoma 8 | 562
progressive supranuclear palsy 8 | 676
Atopic dermatitis 7 | 952
Autosomal recessive predisposition 7 | 1,442
Epilepsy 7 | 792
Stomach Neoplasms 7 | 300
active ulcerative colitis 7 | 764
gastric cancer 7 | 459
hepatocellular carcinoma 7 | 547
Breast Neoplasms 6 | 445
Kidney disease 6 | 430
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
primary Sjogren syndrome 6 | 735
Alzheimer's disease 5 | 658
Asthma 5 | 385
Cleft Palate 5 | 271
Disease Models, Animal 5 | 155
Down syndrome 5 | 499
Dull intelligence 5 | 645
Liver cancer 5 | 604
Low intelligence 5 | 645
Mammary Neoplasms 5 | 425
Melanoma 5 | 711
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple Sclerosis 5 | 540
Neoplasm Metastasis 5 | 168
Osteoporosis 5 | 363
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
atypical teratoid/rhabdoid tumor 5 | 357
nasopharyngeal carcinoma 5 | 1,058
spina bifida 5 | 1,074
Acquired scoliosis 4 | 281
Arthritis 4 | 290
Bipolar Disorder 4 | 666
Chronic Lymphocytic Leukemia 4 | 262
Cognitive delay 4 | 608
Crohn's disease 4 | 321
Curvature of spine 4 | 282
Depressive disorder 4 | 409
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Polycystic ovary syndrome 4 | 360
Uranostaphyloschisis 4 | 167

Tissue

Digestive Tract 86 | 17,369
Endocrine System 86 | 18,159
Skin and soft tissues 86 | 17,230
Nervous System 85 | 16,725
Respiratory system 85 | 16,393
Blood and immune system 84 | 16,909
Female tissues 84 | 17,400
Liver and Pancreas 84 | 16,750
Male tissues 84 | 17,142
Cardiovascular System 83 | 15,192
Urinary Tract 83 | 16,678

Target Family

Non-IDG 52 | 12,091
Enzyme 22 | 4,145
Transcription Factor 9 | 1,400
Kinase 3 | 634
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

UniProt Keyword

ADP-ribosylation 89 | 89
Complete proteome 20,231 | 20,231
Reference proteome 20,231 | 20,231
Polymorphism 12,194 | 12,194
Alternative splicing 10,528 | 10,528
Phosphoprotein 8,216 | 8,216
Membrane 7,361 | 7,361
3D-structure 6,226 | 6,226
Nucleus 5,259 | 5,259
Transmembrane 5,228 | 5,228
Transmembrane helix 5,207 | 5,207
Cytoplasm 4,952 | 4,952
Repeat 4,916 | 4,916
Glycoprotein 4,623 | 4,623
Metal-binding 3,672 | 3,672
Disulfide bond 3,599 | 3,599
Signal 3,561 | 3,561
Acetylation 3,409 | 3,409
Cell membrane 3,390 | 3,390
Direct protein sequencing 2,872 | 2,872
Disease mutation 2,804 | 2,804
Ubl conjugation 2,439 | 2,439
Transcription 2,402 | 2,402
Zinc 2,356 | 2,356
Transcription regulation 2,336 | 2,336
Coiled coil 2,153 | 2,153
Secreted 2,041 | 2,041
DNA-binding 2,008 | 2,008
Transport 1,985 | 1,985
Zinc-finger 1,785 | 1,785
Transferase 1,782 | 1,782
Nucleotide-binding 1,775 | 1,775
Isopeptide bond 1,739 | 1,739
Hydrolase 1,654 | 1,654
Receptor 1,502 | 1,502
ATP-binding 1,380 | 1,380
Cytoskeleton 1,182 | 1,182
Mitochondrion 1,147 | 1,147
Endoplasmic reticulum 1,119 | 1,119
Methylation 973 | 973
Developmental protein 965 | 965
Transducer 887 | 887
Calcium 875 | 875
Golgi apparatus 838 | 838
G-protein coupled receptor 830 | 830
Cell projection 826 | 826
Lipoprotein 825 | 825
Immunity 717 | 717
Cell junction 709 | 709
Differentiation 703 | 703
Ubl conjugation pathway 684 | 684
RNA-binding 682 | 682
Activator 672 | 672
Cell cycle 647 | 647
Kinase 637 | 637
Ion transport 631 | 631
Immunoglobulin domain 625 | 625
Protein transport 612 | 612
Repressor 602 | 602
Sensory transduction 600 | 600
Oxidoreductase 571 | 571
Magnesium 558 | 558
Transit peptide 544 | 544
Cytoplasmic vesicle 535 | 535
Protease 535 | 535
Apoptosis 533 | 533
Endosome 525 | 525
Cell adhesion 482 | 482
Host-virus interaction 472 | 472
Signal-anchor 458 | 458
Olfaction 435 | 435
Lipid metabolism 432 | 432
Chromosome 388 | 388
Serine-threonine-protein kinas... 388 | 388
Cell division 383 | 383
Synapse 378 | 378
DNA damage 366 | 366
Mental retardation 362 | 362
Ion channel 348 | 348
mRNA processing 340 | 340
GTP-binding 339 | 339
Palmitate 331 | 331
Chromosomal rearrangement 324 | 324
Iron 319 | 319
Neurodegeneration 318 | 318
Leucine-rich repeat 312 | 312
DNA repair 306 | 306
Lysosome 301 | 301
Cleavage on pair of basic resi... 298 | 298
Innate immunity 291 | 291
Chromatin regulator 290 | 290
Ribonucleoprotein 286 | 286
Microtubule 281 | 281
Adaptive immunity 280 | 280
WD repeat 277 | 277
Mitochondrion inner membrane 276 | 276
Mitosis 273 | 273
Actin-binding 272 | 272
mRNA splicing 264 | 264
Neurogenesis 260 | 260
ANK repeat 258 | 258

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Desmin DES Tbio Non-IDG -1.56068 36.6 991
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
FACT complex subunit SPT16 SUPT16H Tbio Enzyme -1.85453 70.7 324
Integrin alpha-7 ITGA7 Tbio Non-IDG -1.63563 42.4 193
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 48
Deoxyribonuclease gamma DNASE1L3 Tbio Enzyme -2.31583 207.3 157
Histone H2B type 1-M HIST1H2BM Tdark Non-IDG 0.17 0.33 21
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184
Translation machinery-associated protein 7 TMA7 Tdark Non-IDG -0.57787 4.42 13
Thyroid hormone receptor-associated protein 3 THRAP3 Tbio Non-IDG -0.87769 8.81 136