Development Level

Tchem 116 | 1,890
Tclin 93 | 602
Tbio 71 | 10,625
Tdark 33 | 7,003

Collection

GPCR: IDG Consortium (Targets) 90 | 127
GPCR: IDG Consortium (Complete/Control) 25 | 26

IMPC Phenotype

decreased bone mineral content 6 | 157
decreased bone mineral density 6 | 126
decreased lean body mass 5 | 195
hyperactivity 4 | 108
improved glucose tolerance 4 | 56
increased grip strength 4 | 83
preweaning lethality, complete... 4 | 633
abnormal behavior 3 | 226
abnormal behavioral response t... 3 | 52
abnormal epididymis morphology 3 | 31
decreased body length 3 | 108
decreased body weight 3 | 174
decreased circulating glucose ... 3 | 121
decreased grip strength 3 | 123
decreased total body fat amoun... 3 | 186
increased circulating calcium ... 3 | 32
increased mean corpuscular vol... 3 | 91
increased total body fat amoun... 3 | 57
abnormal bone structure 2 | 131
abnormal kidney morphology 2 | 30
abnormal seminal vesicle morph... 2 | 47
abnormal skin coloration 2 | 18
abnormal sleep behavior 2 | 63
decreased CD8-positive, alpha-... 2 | 26
decreased NK T cell number 2 | 28
decreased circulating HDL chol... 2 | 77
decreased circulating alanine ... 2 | 53
decreased circulating choleste... 2 | 85
decreased circulating insulin ... 2 | 75
decreased heart weight 2 | 44
decreased hemoglobin content 2 | 53
decreased mean corpuscular hem... 2 | 34
decreased prepulse inhibition 2 | 52
enlarged epididymis 2 | 27
enlarged heart 2 | 111
female infertility 2 | 34
hypoactivity 2 | 89
increased circulating HDL chol... 2 | 63
increased circulating alkaline... 2 | 119
increased circulating creatini... 2 | 29
increased circulating sodium l... 2 | 71
increased erythrocyte cell num... 2 | 26
increased exploration in new e... 2 | 56
increased fasted circulating g... 2 | 68
increased heart weight 2 | 37
increased hematocrit 2 | 36
increased hemoglobin content 2 | 45
increased lean body mass 2 | 107
increased monocyte cell number 2 | 27
increased or absent threshold ... 2 | 128
male infertility 2 | 62
preweaning lethality, incomple... 2 | 260
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal liver morphology 1 | 5
abnormal lymph node morphology 1 | 3
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
abnormal skin morphology 1 | 23
abnormal testis morphology 1 | 30
absent pinna reflex 1 | 21
cataract 1 | 26
convulsive seizures 1 | 11
decreased IgE level 1 | 3
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating chloride... 1 | 32
decreased circulating creatini... 1 | 31
decreased circulating triglyce... 1 | 83
decreased hematocrit 1 | 25
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral density 1 | 52
increased caudal vertebrae num... 1 | 8
increased circulating bilirubi... 1 | 16
increased circulating serum al... 1 | 25
increased gamma-delta T cell n... 1 | 16
increased mean corpuscular hem... 1 | 25
increased sacral vertebrae num... 1 | 62
mydriasis 1 | 9
oligodactyly 1 | 14
short tail 1 | 4
short tibia 1 | 82
shortened PQ interval 1 | 6
small kidney 1 | 10
small spleen 1 | 11
small superior vagus ganglion 1 | 20
small testis 1 | 37
small thymus 1 | 11
thrombocytopenia 1 | 46
urinary bladder obstruction 1 | 2

Disease

psoriasis 128 | 6,685
osteosarcoma 100 | 7,933
medulloblastoma, large-cell 84 | 6,234
ovarian cancer 84 | 8,491
glioblastoma 72 | 5,572
interstitial cystitis 62 | 2,299
pilocytic astrocytoma 62 | 3,086
atypical teratoid / rhabdoid tumor 58 | 4,369
lung carcinoma 55 | 2,844
lung cancer 54 | 4,473
invasive ductal carcinoma 52 | 2,950
lung adenocarcinoma 51 | 2,714
oligodendroglioma 49 | 2,849
primitive neuroectodermal tumor 47 | 3,031
malignant mesothelioma 45 | 3,163
ulcerative colitis 44 | 2,087
Schizophrenia 43 | 503
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,988
Obesity 39 | 616
ependymoma 39 | 2,514
non-small cell lung cancer 39 | 2,798
pediatric high grade glioma 39 | 2,712
Cancer 38 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 38 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,956
ductal carcinoma in situ 36 | 1,745
Asthma 35 | 349
adult high grade glioma 35 | 2,148
diabetes mellitus 35 | 1,663
astrocytic glioma 34 | 2,241
Carcinoma 33 | 2,147
pituitary cancer 32 | 1,972
Breast cancer 31 | 3,098
pancreatic cancer 31 | 2,300
breast carcinoma 29 | 1,614
tuberculosis 29 | 1,563
Parkinson's disease 27 | 364
medulloblastoma 27 | 1,524
cutaneous lupus erythematosus 26 | 1,056
Allergic rhinitis 25 | 92
adrenocortical carcinoma 24 | 1,427
astrocytoma 24 | 1,493
colon cancer 24 | 1,475
posterior fossa group A ependymoma 24 | 1,511
group 4 medulloblastoma 23 | 1,875
Epilepsy 22 | 346
primary Sjogren syndrome 22 | 788
subependymal giant cell astrocytoma 22 | 2,287
Migraine 21 | 79
Nasal congestion 21 | 24
sonic hedgehog group medulloblastoma 21 | 1,482
Attention deficit hyperactivity disorder 20 | 156
Multiple Sclerosis 20 | 498
Nasal discharge 20 | 26
Alcohol dependence 19 | 107
Common cold 19 | 63
Major Depressive Disorder 18 | 106
gastric carcinoma 18 | 832
group 3 medulloblastoma 18 | 2,254
mucosa-associated lymphoid tissue lymphoma 18 | 480
Bipolar Disorder 17 | 266
Cocaine-Related Disorders 17 | 88
Pain 17 | 70
cystic fibrosis 17 | 1,670
Pain agnosia 16 | 99
Rheumatoid Arthritis 16 | 1,170
atypical teratoid/rhabdoid tumor 16 | 1,095
posterior fossa group B ependymoma 16 | 1,530
Autistic Disorder 15 | 320
Substance Withdrawal Syndrome 15 | 55
Asthma management 14 | 20
Atopic dermatitis 14 | 944
Hypertension 14 | 293
Hypertensive disease 14 | 193
Status Epilepticus 14 | 85
Bronchitis 13 | 44
Pick disease 13 | 1,893
Pulmonary emphysema 13 | 34
Vascular disease 13 | 281
hepatocellular carcinoma 13 | 550
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,795
primary pancreatic ductal adenocarcinoma 13 | 1,271
Acute exacerbation of asthma 12 | 14
Alzheimer's disease 12 | 644
Cerebrovascular disease 12 | 231
Hyperalgesia 12 | 71
Hypertensive disorder 12 | 58
Influenza-like symptoms 12 | 17
Seizures 12 | 95
esophageal adenocarcinoma 12 | 737
Acromegaly 11 | 40
Amphetamine-Related Disorders 11 | 74
Atherosclerosis 11 | 275
Endometriosis 11 | 535
General anesthesia 11 | 53
Hypotension 11 | 53
Panic disorder 11 | 55
fibroadenoma 11 | 557
glioblastoma multiforme 11 | 347
pancreatic carcinoma 11 | 567

Tissue

Female tissues 305 | 18,646
Nervous System 305 | 18,560
Digestive Tract 304 | 18,472
Urinary Tract 302 | 18,443
Endocrine System 301 | 18,511
Skin and soft tissues 299 | 18,114
Liver and Pancreas 287 | 18,135
Cardiovascular System 283 | 17,957
Male tissues 274 | 17,968
Blood and immune system 268 | 17,994
Respiratory system 268 | 17,483

Target Family

GPCR 313 | 408

TechDev PI

Bryan Roth 313 | 313
Gary Johnson 302 | 302
Jing-Ruey Yeh 64 | 64
Steve Finkbeiner 41 | 41
Jun Qin 39 | 39
Susumu Tomita 37 | 37
Michael McManus 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
5-hydroxytryptamine receptor 1E HTR1E Tchem GPCR -1.54352 34.9 99
Somatostatin receptor type 1 SSTR1 Tclin GPCR -2.13194 126.3 290
Somatostatin receptor type 2 SSTR2 Tclin GPCR -2.51625 341.8 227
G-protein coupled receptor 39 GPR39 Tchem GPCR -1.72902 59.1 216
Motilin receptor MLNR Tchem GPCR -2.15968 125.5 135
Gonadotropin-releasing hormone receptor GNRHR Tclin GPCR -2.61137 425.1 280
P2Y purinoceptor 8 P2RY8 Tbio GPCR -1.00631 7.92 122
Melanocortin receptor 3 MC3R Tchem GPCR -2.63865 450.0 177
Histamine H2 receptor HRH2 Tclin GPCR -3.21045 1579.7 225
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.45436 257.8 324