Development Level

Tbio 11 | 10,625
Tdark 4 | 7,003

IMPC Phenotype

decreased grip strength 2 | 123
increased grip strength 2 | 83
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat-hair pigmentatio... 1 | 54
abnormal lens morphology 1 | 73
aorta dilation 1 | 3
decreased NK cell number 1 | 16
decreased fasted circulating g... 1 | 49
increased granulocyte number 1 | 8
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 8 | 8,491
osteosarcoma 7 | 7,933
group 3 medulloblastoma 6 | 2,254
lung cancer 5 | 4,473
medulloblastoma, large-cell 4 | 6,234
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
glioblastoma 3 | 5,572
pancreatic cancer 3 | 2,300
psoriasis 3 | 6,685
Multiple myeloma 2 | 1,327
Polycystic Ovary Syndrome 2 | 334
Rheumatoid Arthritis 2 | 1,170
Waldenstrons macroglobulinemia 2 | 764
acute myeloid leukemia 2 | 785
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,714
malignant mesothelioma 2 | 3,163
oligodendroglioma 2 | 2,849
primary pancreatic ductal adenocarcinoma 2 | 1,271
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
Breast cancer 1 | 3,098
Cancer 1 | 2,346
Carcinoma 1 | 2,147
Cleft palate 1 | 125
Crohn's disease 1 | 304
Dyskeratosis congenita 1 | 24
Human granulocytic anaplasmosis 1 | 8
Intellectual disability 1 | 573
Mental retardation, autosomal recessive 50 1 | 1
Metabolic syndrome X 1 | 155
Myxoid liposarcoma 1 | 7
Orchitis 1 | 16
Peripheral Neuropathy 1 | 303
Pneumonia 1 | 133
Primary biliary cirrhosis 1 | 45
Schizophrenia 1 | 503
Spinocerebellar ataxia type 2 1 | 19
Syringomyelia 1 | 9
Thoracic outlet syndrome 1 | 8
Ulnar neuropathy 1 | 7
adult high grade glioma 1 | 2,148
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
dermatomyositis 1 | 966
glioblastoma multiforme 1 | 347
gliosarcoma 1 | 19
interleukin-7 receptor alpha deficiency 1 | 16
juvenile dermatomyositis 1 | 1,189
lung carcinoma 1 | 2,844
medulloblastoma 1 | 1,524
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung carcinoma 1 | 413
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
posterior fossa group A ependymoma 1 | 1,511
posterior fossa group B ependymoma 1 | 1,530
primary Sjogren syndrome 1 | 788
sarcoidosis 1 | 368
sonic hedgehog group medulloblastoma 1 | 1,482
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,563
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 15 | 17,994
Cardiovascular System 15 | 17,957
Digestive Tract 15 | 18,472
Endocrine System 15 | 18,511
Female tissues 15 | 18,646
Liver and Pancreas 15 | 18,135
Male tissues 15 | 17,968
Nervous System 15 | 18,560
Urinary Tract 15 | 18,443
Respiratory system 14 | 17,483
Skin and soft tissues 14 | 18,114

Target Family

Non-IDG 12 | 11,969
Enzyme 3 | 4,146

Reactome Pathway

mRNA decay by 5' to 3' exoribo... 15 | 15
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable ATP-dependent RNA helicase DDX6 DDX6 Tbio Enzyme -1.77534 57.8 244
mRNA-decapping enzyme 1A DCP1A Tbio Non-IDG 0.00000 256
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.08986 114.2 45
mRNA-decapping enzyme 1B DCP1B Tdark Non-IDG -0.31352 1.45 90
Enhancer of mRNA-decapping protein 3 EDC3 Tbio Non-IDG -1.39049 24.7 127
m7GpppN-mRNA hydrolase DCP2 Tbio Enzyme -1.91461 80.7 139
U6 snRNA-associated Sm-like protein LSm1 LSM1 Tbio Non-IDG -1.99693 102.2 152
Enhancer of mRNA-decapping protein 4 EDC4 Tbio Non-IDG -2.26154 170.8 91
U6 snRNA-associated Sm-like protein LSm3 LSM3 Tdark Non-IDG -0.72642 5.40 35
U6 snRNA-associated Sm-like protein LSm6 LSM6 Tdark Non-IDG -0.54613 2.65 54