Development Level

Tbio 11 | 10,625
Tdark 4 | 7,003

IMPC Term

decreased grip strength 2 | 123
increased grip strength 2 | 83
preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal coat/hair pigmentatio... 1 | 54
abnormal lens morphology 1 | 73
aorta dilation 1 | 3
decreased NK cell number 1 | 16
decreased fasted circulating g... 1 | 49
increased granulocyte number 1 | 8
increased or absent threshold ... 1 | 128

Disease

ovarian cancer 8 | 8,484
osteosarcoma 7 | 7,933
group 3 medulloblastoma 6 | 2,254
lung cancer 5 | 4,466
medulloblastoma, large-cell 4 | 6,234
acute quadriplegic myopathy 3 | 1,157
atypical teratoid / rhabdoid tumor 3 | 4,369
glioblastoma 3 | 5,572
pancreatic cancer 3 | 2,300
psoriasis 3 | 6,685
Multiple myeloma 2 | 1,327
Polycystic Ovary Syndrome 2 | 332
Rheumatoid Arthritis 2 | 1,160
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 780
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
breast carcinoma 2 | 1,614
diabetes mellitus 2 | 1,663
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
malignant mesothelioma 2 | 3,162
oligodendroglioma 2 | 2,849
primary pancreatic ductal adenocarcinoma 2 | 1,271
primitive neuroectodermal tumor 2 | 3,031
spina bifida 2 | 1,064
Breast cancer 1 | 3,094
Cancer 1 | 2,346
Carcinoma 1 | 2,147
Cleft palate 1 | 125
Crohn's disease 1 | 304
Dyskeratosis congenita 1 | 24
Human granulocytic anaplasmosis 1 | 8
Intellectual disability 1 | 573
Metabolic syndrome X 1 | 155
Myxoid liposarcoma 1 | 5
Orchitis 1 | 16
Peripheral Neuropathy 1 | 303
Pneumonia 1 | 133
Primary biliary cirrhosis 1 | 43
Schizophrenia 1 | 501
Spinocerebellar ataxia type 2 1 | 19
Syringomyelia 1 | 9
Thoracic outlet syndrome 1 | 8
Ulnar neuropathy 1 | 7
adult high grade glioma 1 | 2,148
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
dermatomyositis 1 | 933
glioblastoma multiforme 1 | 347
gliosarcoma 1 | 19
interleukin-7 receptor alpha deficiency 1 | 16
juvenile dermatomyositis 1 | 1,189
lung carcinoma 1 | 2,844
medulloblastoma 1 | 1,524
nasopharyngeal carcinoma 1 | 1,056
non-small cell lung carcinoma 1 | 413
pediatric high grade glioma 1 | 2,712
pilocytic astrocytoma 1 | 3,086
posterior fossa group A ependymoma 1 | 1,511
posterior fossa group B ependymoma 1 | 1,530
primary Sjogren syndrome 1 | 789
sarcoidosis 1 | 358
sonic hedgehog group medulloblastoma 1 | 1,482
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 15 | 17,995
Cardiovascular System 15 | 17,958
Digestive Tract 15 | 18,473
Endocrine System 15 | 18,512
Female tissues 15 | 18,647
Liver and Pancreas 15 | 18,136
Male tissues 15 | 17,969
Nervous System 15 | 18,561
Urinary Tract 15 | 18,444
Respiratory system 14 | 17,484
Skin and soft tissues 14 | 18,115

Target Family

Non-IDG 12 | 11,971
Enzyme 3 | 4,146

Reactome Pathway

mRNA decay by 5' to 3' exoribo... 15 | 15
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
m7GpppN-mRNA hydrolase DCP2 Tbio Enzyme -1.89749 80.7 139
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.06818 114.2 45
mRNA-decapping enzyme 1B DCP1B Tdark Non-IDG -0.31186 1.45 90
U6 snRNA-associated Sm-like protein LSm7 LSM7 Tbio Non-IDG -0.95781 6.58 82
U6 snRNA-associated Sm-like protein LSm1 LSM1 Tbio Non-IDG -1.98325 102.2 152
Enhancer of mRNA-decapping protein 4 EDC4 Tbio Non-IDG -2.21717 170.8 91
U6 snRNA-associated Sm-like protein LSm3 LSM3 Tdark Non-IDG -0.73047 5.40 35
U6 snRNA-associated Sm-like protein LSm6 LSM6 Tdark Non-IDG -0.53572 2.65 54
U6 snRNA-associated Sm-like protein LSm4 LSM4 Tbio Non-IDG -2.14632 139.9 124
U6 snRNA-associated Sm-like protein LSm5 LSM5 Tdark Non-IDG -0.97120 8.80 38