Development Level

Tbio 143 | 10,625
Tdark 25 | 7,003
Tchem 9 | 1,890

IMPC Term

preweaning lethality, complete... 12 | 633
embryonic lethality prior to o... 4 | 148
abnormal behavior 3 | 226
decreased leukocyte cell numbe... 3 | 54
decreased neutrophil cell numb... 3 | 37
embryonic lethality prior to t... 3 | 187
preweaning lethality, incomple... 3 | 260
abnormal coat/hair pigmentatio... 2 | 54
decreased circulating glucose ... 2 | 121
decreased lymphocyte cell numb... 2 | 9
increased fasted circulating g... 2 | 68
prenatal lethality prior to he... 2 | 64
thrombocytosis 2 | 23
abnormal embryo size 1 | 112
abnormal esophagus morphology 1 | 4
abnormal retinal pigmentation 1 | 61
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C high monocyte n... 1 | 18
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased circulating calcium ... 1 | 33
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased gamma-delta T cell n... 1 | 18
decreased grip strength 1 | 123
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased monocyte cell number 1 | 28
enlarged heart 1 | 111
female infertility 1 | 34
hyperactivity 1 | 108
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating glucose ... 1 | 16
increased circulating serum al... 1 | 25
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
increased total body fat amoun... 1 | 57
male infertility 1 | 62
oligodactyly 1 | 14
sparse hair 1 | 6

Disease

ovarian cancer 128 | 8,484
osteosarcoma 86 | 7,933
psoriasis 68 | 6,685
lung cancer 61 | 4,466
medulloblastoma, large-cell 61 | 6,234
Multiple myeloma 52 | 1,327
group 3 medulloblastoma 52 | 2,254
glioblastoma 51 | 5,572
oligodendroglioma 40 | 2,849
ependymoma 39 | 2,514
atypical teratoid / rhabdoid tumor 33 | 4,369
malignant mesothelioma 33 | 3,162
astrocytoma 32 | 1,493
acute quadriplegic myopathy 31 | 1,157
Waldenstrons macroglobulinemia 28 | 765
primitive neuroectodermal tumor 28 | 3,031
diabetes mellitus 26 | 1,663
dermatomyositis 25 | 933
Breast cancer 24 | 3,094
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
Pick disease 21 | 1,893
astrocytic glioma 21 | 2,241
lung adenocarcinoma 21 | 2,713
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
pediatric high grade glioma 19 | 2,712
non-small cell lung cancer 18 | 2,798
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,795
subependymal giant cell astrocytoma 18 | 2,287
Carcinoma 17 | 2,147
progressive supranuclear palsy 17 | 674
Cancer 15 | 2,346
acute myeloid leukemia 14 | 780
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
sonic hedgehog group medulloblastoma 14 | 1,482
atypical teratoid/rhabdoid tumor 13 | 1,095
breast carcinoma 13 | 1,614
Gaucher disease type 1 12 | 171
juvenile dermatomyositis 12 | 1,189
pancreatic cancer 12 | 2,300
Intellectual disability 11 | 573
invasive ductal carcinoma 11 | 2,950
tuberculosis and treatment for 6 months 11 | 686
adult high grade glioma 10 | 2,148
group 4 medulloblastoma 10 | 1,875
hepatocellular carcinoma 10 | 532
non primary Sjogren syndrome sicca 10 | 840
nasopharyngeal carcinoma 9 | 1,056
Amyotrophic Lateral Sclerosis 8 | 431
Rheumatoid Arthritis 8 | 1,160
aldosterone-producing adenoma 8 | 664
HIV Infections 7 | 100
Retinitis pigmentosa 7 | 153
medulloblastoma 7 | 1,524
pituitary cancer 7 | 1,972
Mixed connective tissue disease 6 | 16
Polycystic Ovary Syndrome 6 | 332
Stomach Neoplasms 6 | 282
adrenocortical carcinoma 6 | 1,427
pancreatic carcinoma 6 | 567
posterior fossa group B ependymoma 6 | 1,530
relapsing-remitting multiple sclerosis 6 | 18
Disease Progression 5 | 125
Frontotemporal dementia 5 | 41
Lupus erythematosus 5 | 80
Microcephaly 5 | 149
Subcutaneous panniculitis-like T-cell lymphoma 5 | 16
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
gastric cancer 5 | 430
pilocytic astrocytoma 5 | 3,086
primary pancreatic ductal adenocarcinoma 5 | 1,271
Alzheimer's disease 4 | 644
Animal Mammary Neoplasms 4 | 136
Cockayne syndrome 4 | 54
Immune system cancer 4 | 38
Mammary Neoplasms 4 | 410
Mammary Neoplasms, Experimental 4 | 150
Nager acrofacial dysostosis 4 | 21
colon cancer 4 | 1,475
cystic fibrosis 4 | 1,665
glioblastoma multiforme 4 | 347
inflammatory breast cancer 4 | 404
interstitial lung disease 4 | 291
posterior fossa group A ependymoma 4 | 1,511
primary Sjogren syndrome 4 | 789
spina bifida 4 | 1,064
tuberculosis and treatment for 3 months 4 | 327
Atopic dermatitis 3 | 944
Epilepsy 3 | 346
Hematologic cancer 3 | 9
Melanoma 3 | 261
Neurodegenerative disease 3 | 383
Pneumonia 3 | 133
Spinal muscular atrophy 3 | 24
Spinocerebellar ataxia type 1 3 | 16
Treacher Collins syndrome 3 | 29
active Crohn's disease 3 | 918
ductal carcinoma in situ 3 | 1,745
gastric carcinoma 3 | 832
tuberculosis 3 | 1,557
Schizophrenia 2 | 501

Tissue

Blood and immune system 176 | 17,995
Digestive Tract 176 | 18,473
Endocrine System 176 | 18,512
Female tissues 176 | 18,647
Liver and Pancreas 176 | 18,136
Male tissues 176 | 17,969
Nervous System 176 | 18,561
Respiratory system 176 | 17,484
Cardiovascular System 175 | 17,958
Urinary Tract 175 | 18,444
Skin and soft tissues 174 | 18,115

Target Family

Non-IDG 145 | 11,971
Enzyme 28 | 4,146
Epigenetic 2 | 242
Transcription Factor 2 | 1,400

Reactome Pathway

mRNA Splicing - Major Pathway 177 | 177
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.25254 1.81 65
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 1.33 95
Serine/arginine repetitive matrix protein 2 SRRM2 Tbio Non-IDG -1.90106 71.6 51
Small nuclear ribonucleoprotein E SNRPE Tbio Non-IDG -2.70963 540.8 230
PHD finger-like domain-containing protein 5A PHF5A Tbio Epigenetic -1.94489 96.2 127
ELAV-like protein 2 ELAVL2 Tbio Non-IDG -2.09180 122.7 196
Pre-mRNA-splicing factor 38A PRPF38A Tdark Non-IDG -0.69167 4.80 72
SURP and G-patch domain-containing protein 1 SUGP1 Tbio Non-IDG -2.08366 122.0 109
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.74939 59.4 153
Calcium homeostasis endoplasmic reticulum protein CHERP Tbio Non-IDG -0.65642 6.28 151