Development Level

Tbio 5 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
decreased circulating choleste... 1 | 93
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased grip strength 1 | 41
male infertility 1 | 123
small testis 1 | 58

Disease

ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
medulloblastoma, large-cell 5 | 6,241
osteosarcoma 5 | 7,950
Cancer 4 | 2,499
Hypertension 4 | 396
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
pancreatic cancer 4 | 2,398
Breast Neoplasms 3 | 445
Hyperhomocysteinemia 3 | 37
Liver Cirrhosis, Experimental 3 | 769
Mammary Neoplasms 3 | 425
ductal carcinoma in situ 3 | 1,745
lung adenocarcinoma 3 | 2,716
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Atherosclerosis 2 | 291
Atrial Fibrillation 2 | 124
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Cardiomegaly 2 | 116
Coronary artery disease 2 | 268
Diabetes Mellitus, Experimental 2 | 108
Dull intelligence 2 | 645
Heart disease 2 | 306
Highly variable severity 2 | 157
Hyperinsulinism 2 | 133
Hypertensive disease 2 | 292
Insulin Resistance 2 | 72
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Low intelligence 2 | 645
Lung disease 2 | 142
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Mood Disorders 2 | 184
Multiple myeloma 2 | 1,332
Neoplasm Metastasis 2 | 168
Pick disease 2 | 1,894
Poor school performance 2 | 645
Pre-Eclampsia 2 | 68
Prostatic Neoplasms 2 | 495
Pulmonary hypertension 2 | 85
Retinitis Pigmentosa 2 | 226
Stomach Neoplasms 2 | 300
Variable expressivity 2 | 157
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
Acanthosis Nigricans 1 | 27
Acute chest syndrome 1 | 9
Cerebellar Dysmetria 1 | 56
Chronic Obstructive Airway Disease 1 | 37
Clonus 1 | 18
Diabetic retinopathy 1 | 56
Dyspareunia 1 | 12
Erectile dysfunction 1 | 32
Henoch-Schoenlein purpura 1 | 12
Heredodegenerative Disorders, Nervous System 1 | 3
Hyperglycemia 1 | 137
Hypertension, Pulmonary 1 | 37
Hypertension, Renovascular 1 | 10
Hypertriglyceridemia result 1 | 37
Hypocalcemia 1 | 32
Hypotension, Orthostatic 1 | 18
Idiopathic pulmonary arterial hypertension 1 | 40
Ischemia 1 | 28
Lipodystrophy 1 | 40
Metabolic Syndrome 1 | 20
Myocardial Reperfusion Injury 1 | 37
Neoplasms 1 | 63
Nonepidermolytic palmoplantar keratoderma 1 | 12
Nutrition disease 1 | 3
Ollier disease 1 | 18
Pulmonary Disease, Chronic Obstructive 1 | 31
Sepsis 1 | 24
Serum cholesterol raised 1 | 22
Steatohepatitis 1 | 44
Tachycardia, Ventricular 1 | 22
Uremia 1 | 19

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 3 | 12,091

Reactome Pathway

eNOS activation 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Palmitoyltransferase ZDHHC21 ZDHHC21 Tbio Enzyme -0.65091 4.34 94
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Sepiapterin reductase SPR Tbio Enzyme -1.58814 36.9 174
Acyl-protein thioesterase 1 LYPLA1 Tchem Enzyme -1.83454 68.8 214
Nitric oxide synthase, endothelial NOS3 Tchem Enzyme -3.96497 9525.3 1195
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 DDAH2 Tbio Enzyme -2.11860 122.5 183
Caveolin-1 CAV1 Tbio Non-IDG -3.35685 2432.3 855
Heat shock protein HSP 90-alpha HSP90AA1 Tchem Non-IDG -3.31859 4681.5 1057