Development Level

Tclin 8 | 612
Tchem 5 | 1,885
Tbio 4 | 11,178

Collection

Ion Channel: IDG Consortium (T... 2 | 99

IMPC Phenotype

abnormal duodenum morphology 1 | 4
enlarged heart 1 | 210
enlarged spleen 1 | 41
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 15 | 11,192
medulloblastoma, large-cell 12 | 6,086
atypical teratoid / rhabdoid tumor 9 | 4,971
ependymoma 9 | 4,559
Atrial Fibrillation 8 | 120
Chronic heart failure 8 | 44
Myocardial Perfusion Imaging Adjunct 8 | 25
Platelet Aggregation Inhibition 8 | 22
Prevention of Cerebral Thrombosis 8 | 29
invasive ductal carcinoma 8 | 2,867
oligodendroglioma 8 | 2,768
ovarian cancer 8 | 8,297
Breast cancer 7 | 3,469
Kidney cancer 7 | 2,548
adult high grade glioma 7 | 3,701
astrocytic glioma 7 | 2,530
colon cancer 7 | 1,428
glioblastoma 7 | 5,635
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,204
lung cancer 7 | 4,607
malignant mesothelioma 7 | 3,135
Astrocytoma, Pilocytic 6 | 3,006
Impotence 6 | 44
breast carcinoma 6 | 1,589
lung carcinoma 6 | 2,755
osteosarcoma 6 | 7,766
group 3 medulloblastoma 5 | 4,002
lung adenocarcinoma 5 | 2,627
pituitary cancer 5 | 1,915
primitive neuroectodermal tumor 5 | 2,957
Hypertensive disease 4 | 278
Pick disease 4 | 1,856
group 4 medulloblastoma 4 | 1,806
interstitial cystitis 4 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,902
non-small cell lung cancer 4 | 2,799
psoriasis 4 | 6,514
ulcerative colitis 4 | 1,765
Asthma 3 | 370
Bipolar Disorder 3 | 646
Hypertension 3 | 372
Increase in blood pressure 3 | 118
Pulmonary hypertension 3 | 85
Rheumatoid arthritis 3 | 1,156
cystic fibrosis 3 | 1,629
diabetes mellitus 3 | 1,683
ductal carcinoma in situ 3 | 1,686
medulloblastoma 3 | 702
subependymal giant cell astrocytoma 3 | 2,230
Acquired metabolic disease 2 | 329
Acute heart failure 2 | 2
Benign prostatic hyperplasia 2 | 7
Coronary artery disease 2 | 253
Depressive disorder 2 | 401
Gout 2 | 103
Hypertension, Pulmonary 2 | 36
Hypogonadism 2 | 169
Major Depressive Disorder 2 | 293
Mental Depression 2 | 325
Multiple Sclerosis 2 | 527
Obesity 2 | 655
Osteoporosis 2 | 348
Psychotic Disorders 2 | 150
Short stature 2 | 514
Weight Gain 2 | 95
cutaneous lupus erythematosus 2 | 1,016
fibroadenoma 2 | 538
interstitial lung disease 2 | 287
pancreatic cancer 2 | 2,322
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,911
tuberculosis 2 | 1,963
Aortic aneurysm 1 | 33
Bone Diseases, Metabolic 1 | 13
Brain cancer 1 | 30
Celiac disease 1 | 110
Conduct disorder 1 | 32
Decompensated cardiac failure 1 | 9
Hamman-Rich syndrome 1 | 34
Hyperkyphosis 1 | 109
Hypoactive sexual desire disorder 1 | 8
Kyphosis deformity of spine 1 | 112
Linear atrophy 1 | 15
Metabolic Bone Disorder 1 | 10
Multiple system atrophy 1 | 28
Nonorganic psychosis 1 | 83
Obesity, Abdominal 1 | 23
Onchocerciasis 1 | 10
Peyronie's disease 1 | 9
Pharyngitis 1 | 16
Precancerous Conditions 1 | 78
Priapism 1 | 5
Primary pigmented nodular adrenocortical disease 1 | 13
Prostatic hypertrophy 1 | 8
Pulmonary emphysema 1 | 44
Round, full face 1 | 43
Secretory diarrhea 1 | 10
Stuttering 1 | 17
Tonic - clonic seizures 1 | 43
Toxic shock syndrome 1 | 27

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Enzyme 9 | 4,145
Ion Channel 5 | 344
Kinase 2 | 634
Non-IDG 1 | 12,091

Reactome Pathway

cGMP effects 17 | 17
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

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