Development Level

Tbio 9 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased heart rate 1 | 23
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

ovarian cancer 9 | 8,520
psoriasis 8 | 6,694
Carcinoma 7 | 11,493
malignant mesothelioma 7 | 3,232
osteosarcoma 6 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Atopic dermatitis 5 | 952
medulloblastoma, large-cell 5 | 6,241
Adrenoleukodystrophy 4 | 29
Obesity 4 | 678
Rheumatoid arthritis 4 | 1,191
Zellweger syndrome 4 | 37
active ulcerative colitis 4 | 764
alpha-methylacyl-CoA racemase deficiency 4 | 9
lung cancer 4 | 4,740
progressive supranuclear palsy 4 | 676
Breast cancer 3 | 3,578
Chondrodysplasia punctata 3 | 41
Multiple myeloma 3 | 1,332
Peroxisomal acyl-CoA oxidase deficiency 3 | 4
Schizophrenia 3 | 1,160
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
ependymoma 3 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Bifunctional peroxisomal enzyme deficiency 2 | 3
Chemical and Drug Induced Liver Injury 2 | 195
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Concave bridge of nose 2 | 195
Congenital Epicanthus 2 | 177
D-bifunctional protein deficiency 2 | 3
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diabetes Mellitus, Experimental 2 | 108
Down syndrome 2 | 499
Dystonia 2 | 164
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Frontal bossing 2 | 157
Global developmental delay 2 | 608
Hepatic enzyme increased 2 | 81
Hepatomegaly 2 | 285
Infantile onset 2 | 238
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Low set ears 2 | 181
Mental and motor retardation 2 | 608
Metabolic syndrome X 2 | 52
Neonatal Hypotonia 2 | 64
Nystagmus 2 | 317
Orbital separation excessive 2 | 244
Pediatric failure to thrive 2 | 365
Refsum disease 2 | 20
Seizures 2 | 596
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
atypical teratoid / rhabdoid tumor 2 | 5,112
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
glioblastoma 2 | 5,792
group 4 medulloblastoma 2 | 1,855
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Animal Mammary Neoplasms 1 | 136
Autosomal dominant cerebellar ataxia 1 | 33
Big calvaria 1 | 147
Cerebellar hypoplasia and atrophy 1 | 41
Extinguished electroretinogram 1 | 15
Increased size of cranium 1 | 147
Leukodystrophy 1 | 55
Leukoencephalopathies 1 | 29
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Neonatal adrenoleukodystrophy 1 | 14
Osteoporosis 1 | 363
Retrognathia 1 | 54
Sensorineural hearing loss 1 | 106
West Syndrome 1 | 28

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 11 | 15,192

Target Family

Enzyme 6 | 4,145
Non-IDG 6 | 12,091

Reactome Pathway

alpha-linolenic (omega3) and l... 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Elongation of very long chain fatty acids protein 1 ELOVL1 Tbio Non-IDG -1.29305 16.7 156
Elongation of very long chain fatty acids protein 5 ELOVL5 Tbio Non-IDG -1.90493 83.7 237
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Peroxisomal multifunctional enzyme type 2 HSD17B4 Tbio Non-IDG -2.17283 152.2 275
Long-chain-fatty-acid--CoA ligase 1 ACSL1 Tbio Enzyme -2.59850 388.5 222
Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 Tbio Enzyme -2.10178 116.1 292
Elongation of very long chain fatty acids protein 3 ELOVL3 Tchem Non-IDG -1.31974 18.8 98
Non-specific lipid-transfer protein SCP2 Tchem Non-IDG -2.66328 485.4 314
3-ketoacyl-CoA thiolase, peroxisomal ACAA1 Tbio Enzyme -2.31883 203.8 197