Development Level

Tbio 11 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal cecum morphology 1 | 7
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hydrops fetalis 1 | 1
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating phosphat... 1 | 26
microphthalmia 1 | 26
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

ovarian cancer 11 | 8,520
Carcinoma 10 | 11,493
psoriasis 10 | 6,694
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
lung cancer 5 | 4,740
medulloblastoma, large-cell 5 | 6,241
Cancer 4 | 2,499
adult high grade glioma 4 | 3,801
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
invasive ductal carcinoma 4 | 2,951
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Cataract 8 multiple types 3 | 33
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
astrocytic glioma 3 | 2,597
lung adenocarcinoma 3 | 2,716
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cardiomegaly 2 | 116
Depressive disorder 2 | 409
Intellectual disability 2 | 1,016
Leber congenital amaurosis 2 | 69
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Pain agnosia 2 | 104
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Slow progression 2 | 89
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
head and neck cancer 2 | 271
head and neck cancer and chronic obstructive pulmonary disease 2 | 239
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
sonic hedgehog group medulloblastoma 2 | 467
subependymal giant cell astrocytoma 2 | 2,287
Acute contagious conjunctivitis 1 | 7
Arachnodactyly 1 | 49
Ataxia, Spinocerebellar 1 | 16
Autosomal dominant Robinow syndrome 1 1 | 15
Broad thumbs 1 | 28
Calcium pyrophosphate deposition disease 1 | 13
Cell Transformation, Neoplastic 1 | 97
Cerebellar Dysmetria 1 | 56
Cocaine Dependence 1 | 51
Common variable immunodeficiency 1 | 101
Decreased projection of midface 1 | 105
Deglutition Disorders 1 | 132
Diabetes Mellitus, Experimental 1 | 108
Female Urogenital Diseases 1 | 18
Forgetful 1 | 40
Hypercalcemia 1 | 59
Hyperglycemia 1 | 137
Hypoparathyroidism 1 | 41
Hypotrophic midface 1 | 105
Inadequate arch length for tooth size 1 | 45
Intestinal Neoplasms 1 | 12
Late tooth eruption 1 | 61
Lipoma 1 | 32
Memory Loss 1 | 40
Memory impairment 1 | 40
Midface retrusion 1 | 105
Neoplastic Cell Transformation 1 | 89
Nephrogenic Diabetes Insipidus 1 | 16
Nonorganic psychosis 1 | 84
Norrie disease 1 | 14
Pancreatitis 1 | 123
Pigmentary retinal degeneration 1 | 11
Polyuria 1 | 23
Progressive cerebellar ataxia 1 | 13
Retinal Neovascularization 1 | 4
Retinal exudates 1 | 11
Robinow syndrome 1 | 11
Short hands 1 | 50
Small midface 1 | 105
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Trigeminal Neuralgia 1 | 24

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Skin and soft tissues 14 | 17,230
Cardiovascular System 13 | 15,192
Respiratory system 13 | 16,393
Urinary Tract 13 | 16,678

Target Family

Non-IDG 10 | 12,091
Kinase 3 | 634
GPCR 1 | 408

Reactome Pathway

WNT5A-dependent internalizatio... 14 | 14
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Clathrin light chain A CLTA Tbio Non-IDG -1.32676 16.0 244
Clathrin light chain B CLTB Tbio Non-IDG -2.29105 193.6 153
Protein Wnt-5a WNT5A Tbio Non-IDG -2.77525 650.2 321
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212
Frizzled-4 FZD4 Tbio GPCR -2.05508 106.8 313
AP-2 complex subunit alpha-2 AP2A2 Tbio Non-IDG -0.65996 4.74 124
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108