Development Level

Tclin 5 | 613
Tbio 2 | 11,445

IMPC Phenotype

decreased fasted circulating g... 1 | 65

Disease

Cancer 7 | 2,499
malignant mesothelioma 6 | 3,232
glioblastoma 5 | 5,792
Age related macular degeneration 4 | 72
Breast cancer 4 | 3,578
Carcinoma 4 | 11,493
Diabetic retinopathy 4 | 56
Keratitis 4 | 62
Kuhnt-Junius degeneration 4 | 14
Lymphedema 4 | 42
Metastasis from malignant tumor of colon 4 | 8
cystic fibrosis 4 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Atherosclerosis 3 | 291
Branch retinal vein occlusion with macular edema 3 | 4
Breast Neoplasms 3 | 445
Capillary hemangioma 3 | 12
Central retinal vein occlusion with macular edema 3 | 4
Coronary artery disease 3 | 268
Diabetic macular edema 3 | 7
Exudative age-related macular degeneration 3 | 3
Hemangioma 3 | 69
Hemangiosarcoma 3 | 18
Hypertension 3 | 396
Mammary Neoplasms 3 | 425
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
psoriasis 3 | 6,694
Adenocarcinoma 2 | 122
Angiosarcoma 2 | 11
Carcinoma of thyroid 2 | 17
Cerebral Hemorrhage 2 | 42
Cerebrovascular disease 2 | 238
Clear-cell metastatic renal cell carcinoma 2 | 4
Diabetic Nephropathies 2 | 37
Diabetic Nephropathy 2 | 34
Epilepsy, Temporal Lobe 2 | 23
Exanthem 2 | 37
Follicular thyroid carcinoma 2 | 14
Gastrointestinal stromal tumor 2 | 62
Glaucoma 2 | 239
HEMANGIOMA, CAPILLARY INFANTILE 2 | 3
Hamman-Rich syndrome 2 | 34
Heart disease 2 | 306
Hennekam syndrome 2 | 7
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Limb ischemia 2 | 15
Liver cell carcinoma 2 | 15
Lymphangioma 2 | 9
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Milroy Disease 2 | 3
Myocardial Ischemia 2 | 169
Neovascularization, Pathologic 2 | 6
Osteochondrodysplasias 2 | 72
Ovarian hyperstimulation syndrome 2 | 19
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pancreatic Neuroendocrine Tumor 2 | 45
Papillary thyroid carcinoma 2 | 43
Pathologic Neovascularization 2 | 6
Polycystic ovary syndrome 2 | 360
Proteinuria 2 | 144
Renal Cell Carcinoma 2 | 214
Reperfusion Injury 2 | 86
Retinal vein occlusion 2 | 9
Retinopathy of prematurity 2 | 22
Sarcoma of soft tissue 2 | 11
Schizophrenia 2 | 1,160
Strawberry nevus of skin 2 | 10
Testicular Hydrocele 2 | 8
atypical teratoid / rhabdoid tumor 2 | 5,112
chronic rhinosinusitis 2 | 512
ductal carcinoma in situ 2 | 1,745
fibroadenoma 2 | 559
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819
Arthritis, Experimental 1 | 39
Carcinoma, Pancreatic Ductal 1 | 20
Gastrointestinal system disease 1 | 54
Head and Neck Neoplasms 1 | 26
Hyperglycemia 1 | 137
Liver Neoplasms, Experimental 1 | 59
Lymphangioleiomyomatosis 1 | 16
Lymphatic obstruction 1 | 21
Onset of lymphedema around puberty 1 | 21
Precancerous Conditions 1 | 80
Urologic Neoplasms 1 | 8
Uveitis 1 | 103

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 5 | 12,091
Kinase 2 | 634

Reactome Pathway

VEGF binds to VEGFR leading to... 7 | 7
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vascular endothelial growth factor receptor 3 FLT4 Tclin Kinase -2.72966 518.8 744
Vascular endothelial growth factor C VEGFC Tbio Non-IDG -2.99495 1028.1 667
Placenta growth factor PGF Tclin Non-IDG -3.52194 3429.0 630
Vascular endothelial growth factor receptor 2 KDR Tclin Kinase -3.67555 4544.8 2373
Vascular endothelial growth factor D VEGFD Tbio Non-IDG -2.45080 283.2 498
Vascular endothelial growth factor B VEGFB Tclin Non-IDG -2.39843 237.0 389
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809