Development Level

Tbio 6 | 11,445
Tchem 2 | 1,598
Tclin 1 | 613

Disease

Argininosuccinic aciduria 6 | 17
Carcinoma 6 | 11,493
Hyperammonemia 6 | 30
Cognitive delay 5 | 608
Comatose 5 | 56
Dull intelligence 5 | 645
Failure to gain weight 5 | 365
Global developmental delay 5 | 608
Intellectual disability 5 | 1,016
Lethargy 5 | 77
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Ornithine translocase deficiency 5 | 7
Pediatric failure to thrive 5 | 365
Poor school performance 5 | 645
Protein avoidance 5 | 5
Alkalosis, Respiratory 4 | 5
Autosomal recessive predisposition 4 | 1,442
Brain Edema 4 | 50
Cerebral Edema 4 | 30
Citrullinemia 4 | 14
Epilepsy 4 | 792
Episodic ammonia intoxication 4 | 4
Irritation - emotion 4 | 68
Seizures 4 | 596
Urea cycle disorder 4 | 7
Vomiting 4 | 116
adult high grade glioma 4 | 3,801
medulloblastoma, large-cell 4 | 6,241
Abnormal urinary amino-acid findings 3 | 38
Aminoaciduria 3 | 38
Arginine deficiency 3 | 3
Cerebellar Ataxia 3 | 304
Hepatomegaly 3 | 285
High plasma glutamine 3 | 3
Hyperargininemia 3 | 8
Hypoargininemia 3 | 3
Ornithine carbamoyltransferase deficiency 3 | 12
Orotic aciduria 3 | 18
Tyrosinemia type II 3 | 7
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Carbamoyl phosphate synthetase I deficiency disease 2 | 3
Endotoxemia 2 | 8
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Low plasma citrulline 2 | 2
Muscle hypotonia 2 | 571
Neonatal onset 2 | 21
Phenotypic variability 2 | 150
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
nephrosclerosis 2 | 333
osteosarcoma 2 | 7,950
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
Barrett's esophagus 1 | 182
Brain disease 1 | 96
Decreased liver function 1 | 24
Decreased nerve conduction velocity 1 | 35
Decreased vibratory sense 1 | 7
Diabetic Angiopathies 1 | 16
Epilepsies, Myoclonic 1 | 32
Fibrosis, Liver 1 | 32
Generalized myoclonic seizures 1 | 30
Leber congenital amaurosis 1 1 | 6
Liver Failure 1 | 73
Liver dysfunction, mild 1 | 24
Mucoepidermoid carcinoma 1 | 26
Myoclonic Epilepsies, Progressive 1 | 44
Necrosis 1 | 53
Neonatal abstinence syndrome 1 | 11
Nerve Degeneration 1 | 121
Pulmonary hypertension 1 | 85
Pyloric Stenosis 1 | 47
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Retinal depigmentation 1 | 12
Specific learning disability 1 | 47
hereditary spastic paraplegia 1 | 318
limb girdle muscular dystrophy 2B 1 | 40
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 6 months 1 | 409

Tissue

Endocrine System 9 | 18,159
Blood and immune system 8 | 16,909
Digestive Tract 8 | 17,369
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678
Cardiovascular System 7 | 15,192

Target Family

Enzyme 6 | 4,145
Transporter 2 | 473
Non-IDG 1 | 12,091

Reactome Pathway

Urea cycle 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NmrA-like family domain-containing protein 1 NMRAL1 Tbio Non-IDG -0.93702 11.0 67
Arginase-2, mitochondrial ARG2 Tchem Enzyme -2.46702 275.2 245
Argininosuccinate lyase ASL Tbio Enzyme -2.13476 130.8 199
Carbamoyl-phosphate synthase [ammonia], mitochondrial CPS1 Tclin Enzyme -2.28267 188.9 238
N-acetylglutamate synthase, mitochondrial NAGS Tbio Enzyme -2.39207 245.7 52
Mitochondrial ornithine transporter 1 SLC25A15 Tbio Transporter -2.21589 161.5 45
Mitochondrial ornithine transporter 2 SLC25A2 Tbio Transporter -0.47105 2.47 91
Ornithine carbamoyltransferase, mitochondrial OTC Tchem Enzyme -2.21752 151.7 480
Argininosuccinate synthase ASS1 Tbio Enzyme -2.30801 186.1 322