Development Level

Tbio 8 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal vocalization 1 | 21
enlarged lymph nodes 1 | 37
hydrometra 1 | 53
increased mean platelet volume 1 | 45
increased red blood cell distr... 1 | 34
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 11 | 11,493
psoriasis 6 | 6,694
Obesity 5 | 678
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung cancer 4 | 4,740
Atopic dermatitis 3 | 952
Duchenne muscular dystrophy 3 | 601
Fatty liver disease 3 | 103
Lipodystrophy 3 | 40
breast carcinoma 3 | 1,638
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Aland Island eye disease 2 | 11
Autosomal recessive nonsyndromic deafness 8 2 | 6
Autosomal recessive predisposition 2 | 1,442
Becker muscular dystrophy 2 | 191
Chromosome Xp21 deletion syndrome 2 | 8
Fever 2 | 138
Glycerol kinase deficiency 2 | 10
Hemiplegia 2 | 25
Hypogonadotropic hypogonadism 2 | 89
Kidney cancer 2 | 2,613
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Myalgia 2 | 54
Pick disease 2 | 1,894
X-linked adrenal hypoplasia congenita 2 | 11
active Crohn's disease 2 | 922
adult high grade glioma 2 | 3,801
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
invasive ductal carcinoma 2 | 2,951
medulloblastoma, large-cell 2 | 6,241
osteosarcoma 2 | 7,950
ovarian cancer 2 | 8,520
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Acne 1 | 52
Acute kidney injury 1 | 70
Amyotrophic lateral sclerosis 1 | 451
Arthralgia 1 | 90
Bone pain 1 | 42
Cachexia 1 | 50
Chemical and Drug Induced Liver Injury 1 | 195
Cholestasis 1 | 155
Comatose 1 | 56
Congenital dyserythropoietic anemia 1 | 18
Congenital hemolytic anemia 1 | 32
Creatine phosphokinase serum increased 1 | 110
Decreased tendon reflex 1 | 122
Diabetes Mellitus, Experimental 1 | 108
Diarrhea 1 | 253
Edema 1 | 81
Elevated creatine kinase 1 | 110
Epilepsy 1 | 792
Failure to gain weight 1 | 365
Frontal bossing 1 | 157
Gaucher disease type 1 1 | 180
Headache 1 | 37
Hepatomegaly 1 | 285
Hypercholesterolemia 1 | 44
Hyperkalemia 1 | 17
Hyperlipidemia 1 | 43
Hypertriglyceridemia 1 | 17
Hypertriglyceridemia result 1 | 37
Hypoalbuminemia 1 | 24
Hypoglycemia 1 | 152
Lethargy 1 | 77
Low Birth Weights 1 | 69
Melanoma 1 | 711
Metabolic acidosis 1 | 90
Microcytic hypochromic anemia (disorder) 1 | 10
Muscle Weakness 1 | 170
Muscle biopsy shows dystrophic changes 1 | 39
Muscular dystrophy 1 | 75
Myoglobinuria 1 | 15
Myopathy 1 | 185
Osteomyelitis 1 | 42
Osteoporosis 1 | 363
Otitis Media 1 | 52
Pathological fracture 1 | 20
Pediatric failure to thrive 1 | 365
Pimples 1 | 10
Protein-Losing Enteropathies 1 | 4
Reflex, Deep Tendon, Absent 1 | 92
Refractive error 1 | 50
Seizures 1 | 596
Sengers syndrome 1 | 18
Serum cholesterol raised 1 | 22
Small for gestational age (disorder) 1 | 69
Strabismus 1 | 270
Vomiting 1 | 116
X- linked recessive 1 | 110
X-linked dominant 1 | 57
active ulcerative colitis 1 | 764
hereditary spastic paraplegia 1 | 318
pustule 1 | 10
tuberculosis 1 | 2,010

Tissue

Endocrine System 12 | 18,159
Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192
Nervous System 10 | 16,725
Respiratory system 10 | 16,393

Target Family

Enzyme 10 | 4,145
Kinase 3 | 634

Reactome Pathway

Triglyceride biosynthesis 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Diacylglycerol O-acyltransferase 2 DGAT2 Tchem Enzyme -2.07482 112.0 230
2-acylglycerol O-acyltransferase 1 MOGAT1 Tbio Enzyme -1.07460 11.2 80
2-acylglycerol O-acyltransferase 3 MOGAT3 Tbio Enzyme -1.00860 10.7 81
Phosphatidate phosphatase LPIN2 LPIN2 Tbio Enzyme -1.50639 30.9 152
Diacylglycerol O-acyltransferase 1 DGAT1 Tclin Enzyme -2.74425 562.7 211
Phosphatidate phosphatase LPIN1 LPIN1 Tbio Enzyme -2.13963 149.5 280
Glycerol kinase 3 GK3P Tdark Kinase -1.84692 109.0 0
Glycerol-3-phosphate acyltransferase 2, mitochondrial GPAT2 Tbio Enzyme -0.97159 8.93 38
Phosphatidate phosphatase LPIN3 LPIN3 Tbio Enzyme -1.43940 24.6 88