Development Level

Tbio 26 | 11,651
Tchem 7 | 1,388
Tdark 4 | 6,593
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal embryo size 2 | 220
decreased circulating choleste... 2 | 93
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
cleft palate 1 | 8
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased large unstained cell... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
protruding tongue 1 | 3
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 27 | 11,493
ovarian cancer 16 | 8,520
osteosarcoma 14 | 7,950
lung cancer 12 | 4,740
glioblastoma 11 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
malignant mesothelioma 11 | 3,232
psoriasis 11 | 6,694
Autosomal recessive predisposition 9 | 1,442
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pituitary cancer 9 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
medulloblastoma, large-cell 8 | 6,241
non-small cell lung cancer 8 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
lung adenocarcinoma 7 | 2,716
pancreatic cancer 7 | 2,398
Breast cancer 6 | 3,578
Cancer 6 | 2,499
Cholestasis 6 | 155
adrenocortical carcinoma 6 | 1,428
lung carcinoma 6 | 2,843
Rheumatoid arthritis 5 | 1,191
active ulcerative colitis 5 | 764
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
Bilirubin metabolic disorder 4 | 41
Muscle hypotonia 4 | 571
Pneumonia 4 | 174
Small head 4 | 374
active Crohn's disease 4 | 922
diabetes mellitus 4 | 1,728
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
subependymal giant cell astrocytoma 4 | 2,287
Cerebral atrophy 3 | 178
Cognitive delay 3 | 608
Congenital disorder of glycosylation 3 | 54
Epilepsy 3 | 792
Global developmental delay 3 | 608
Hypothyroidism 3 | 122
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Nystagmus 3 | 317
Obesity 3 | 678
Otitis Media 3 | 52
Pick disease 3 | 1,894
Seizures 3 | 596
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
pediatric high grade glioma 3 | 1,064
Abnormality of metabolism/homeostasis 2 | 134
Absent speech 2 | 43
Adverse reaction to drug 2 | 61
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Attention deficit hyperactivity disorder 2 | 278
Babinski Reflex 2 | 100
Big calvaria 2 | 147
Bipolar Disorder 2 | 666
Coarse facial features 2 | 108
Congenital deafness 2 | 185
Deafness 2 | 198
Degenerative brain disorder 2 | 100
Depressive disorder 2 | 409
Diarrhea 2 | 253
Fever 2 | 138
Hearing Loss, Partial 2 | 185
Icterus 2 | 82
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Neonatal Jaundice 2 | 30
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Paraplegia 2 | 74
Severe mental retardation (I.Q. 20-34) 2 | 99
Skeletal muscle atrophy 2 | 139
Spastic Paraplegia 2 | 42
Supratentorial atrophy 2 | 94
Thickened facial skin with coarse facial features 2 | 108
Type 2 diabetes mellitus 2 | 272
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
hearing impairment 2 | 199
muscle degeneration 2 | 139
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
nonverbal 2 | 43
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Female tissues 37 | 17,400
Endocrine System 36 | 18,159
Male tissues 36 | 17,142
Digestive Tract 35 | 17,369
Urinary Tract 35 | 16,678
Liver and Pancreas 34 | 16,750
Nervous System 34 | 16,725
Blood and immune system 33 | 16,909
Skin and soft tissues 32 | 17,230
Cardiovascular System 31 | 15,192
Respiratory system 31 | 16,393

Target Family

Transporter 31 | 473
Non-IDG 7 | 12,091

Reactome Pathway

Transport of vitamins, nucleos... 38 | 38
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Solute carrier organic anion transporter family member 1B1 SLCO1B1 Tchem Transporter -2.77788 574.0 124
Equilibrative nucleoside transporter 1 SLC29A1 Tclin Transporter -2.61544 427.2 413
Vasopressin-neurophysin 2-copeptin AVP Tbio Non-IDG -3.92570 8381.2 203
Long-chain fatty acid transport protein 4 SLC27A4 Tchem Transporter -1.79305 59.1 93
Long-chain fatty acid transport protein 6 SLC27A6 Tbio Transporter -1.72807 51.7 56
GDP-fucose transporter 1 SLC35C1 Tbio Transporter -1.06011 11.8 43
Acetyl-coenzyme A transporter 1 SLC33A1 Tchem Transporter -1.17769 16.1 114
PDZ domain-containing protein 11 PDZD11 Tbio Non-IDG -2.04712 109.9 49
Epididymal-specific lipocalin-12 LCN12 Tdark Non-IDG -0.38322 2.46 41
UDP-xylose and UDP-N-acetylglucosamine transporter SLC35B4 Tbio Transporter -1.26168 16.6 19