Development Level

Tbio 7 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal embryo size 2 | 220
preweaning lethality, complete... 2 | 979
abnormal body wall morphology 1 | 9
abnormal facial morphology 1 | 17
abnormal forebrain development 1 | 20
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal limb morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal tail morphology 1 | 25
cleft palate 1 | 8
decreased circulating choleste... 1 | 93
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased lean body mass 1 | 172
protruding tongue 1 | 3
unresponsive to tactile stimul... 1 | 8

Disease

ovarian cancer 6 | 8,520
Carcinoma 4 | 11,493
glioblastoma 4 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Epilepsy 3 | 792
Muscle hypotonia 3 | 571
Seizures 3 | 596
Small head 3 | 374
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Cerebral atrophy 2 | 178
Cognitive delay 2 | 608
Congenital disorder of glycosylation 2 | 54
Global developmental delay 2 | 608
Mental and motor retardation 2 | 608
atypical teratoid / rhabdoid tumor 2 | 5,112
lung cancer 2 | 4,740
pituitary cancer 2 | 1,972
Abnormality of metabolism/homeostasis 1 | 134
Abnormality of the fingernails 1 | 51
Acquired metabolic disease 1 | 336
Arthrogryposis 1 | 54
Autism Spectrum Disorders 1 | 75
Autistic behavior 1 | 20
Barrett's esophagus 1 | 182
Big calvaria 1 | 147
Bilirubin metabolic disorder 1 | 41
Brachydactyly 1 | 156
Brain cancer 1 | 30
Bushy eyebrows 1 | 49
Coarse facial features 1 | 108
Craniofacial Abnormalities 1 | 151
Decreased projection of midface 1 | 105
Degenerative brain disorder 1 | 100
Delayed myelination 1 | 22
Dextrocardia 1 | 12
Diarrhea 1 | 253
Epileptic encephalopathy 1 | 26
Fibular hypoplasia 1 | 9
Flexion contracture of proximal interphalangeal joint 1 | 75
Gingival Diseases 1 | 19
Hepatitis D 1 | 10
Hooked clavicle 1 | 5
Hypoplasia of corpus callosum 1 | 90
Hypoplastic ilia 1 | 12
Hypoplastic toenails 1 | 22
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Hypsarrhythmia 1 | 25
Increased fibular diameter 1 | 4
Increased head circumference 1 | 147
Increased size of cranium 1 | 147
Increased size of skull 1 | 147
Infantile onset 1 | 238
Leukocyte adhesion deficiency 1 | 16
Long narrow head 1 | 75
Lymphatic obstruction 1 | 21
Lymphedema 1 | 42
Lymphoma 1 | 81
Malar flattening 1 | 129
Metaphyseal irregularity 1 | 23
Microretrognathia 1 | 13
Midface retrusion 1 | 105
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Narrow thorax 1 | 53
Neonatal Jaundice 1 | 30
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant 1 | 6
Neutropenia 1 | 72
Onset of lymphedema around puberty 1 | 21
Open mouth 1 | 45
Otitis Media 1 | 52
Parietal foramina 1 | 10
Periodontal Diseases 1 | 21
Pneumonia 1 | 174
Polyhydramnios 1 | 108
Progressive mental retardation 1 | 37
Recurrent infections 1 | 48
Retinitis pigmentosa 4 1 | 38
Severe mental retardation (I.Q. 20-34) 1 | 99
Short limb dwarfism, disproportionate 1 | 22
Short ribs 1 | 30
Small midface 1 | 105
Small wings of the pelvic girdle 1 | 12
Stillbirth 1 | 17
Supratentorial atrophy 1 | 94
Thick vermilion border 1 | 25
Thickened facial skin with coarse facial features 1 | 108
Turridolichocephaly 1 | 75
Urogenital tuberculosis 1 | 2
X-linked dominant 1 | 57
active ulcerative colitis 1 | 764
ventricular septal defect 1 | 20

Tissue

Blood and immune system 8 | 16,909
Cardiovascular System 8 | 15,192
Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Liver and Pancreas 8 | 16,750
Male tissues 8 | 17,142
Nervous System 8 | 16,725
Respiratory system 8 | 16,393
Skin and soft tissues 8 | 17,230
Urinary Tract 8 | 16,678

Target Family

Transporter 8 | 473

Reactome Pathway

Transport of nucleotide sugars 8 | 8
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter SLC35D2 Tbio Transporter -1.58749 38.8 59
UDP-xylose and UDP-N-acetylglucosamine transporter SLC35B4 Tbio Transporter -1.26168 16.6 19
Adenosine 3'-phospho 5'-phosphosulfate transporter 2 SLC35B3 Tdark Transporter -0.76124 5.53 7
Adenosine 3'-phospho 5'-phosphosulfate transporter 1 SLC35B2 Tbio Transporter -2.30841 191.5 77
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter SLC35D1 Tbio Transporter -0.77614 5.86 105
UDP-N-acetylglucosamine transporter SLC35A3 Tbio Transporter -1.92946 75.3 50
GDP-fucose transporter 1 SLC35C1 Tbio Transporter -1.06011 11.8 43
UDP-galactose translocator SLC35A2 Tbio Transporter -2.99582 934.5 32