Development Level

Tbio 88 | 11,651
Tchem 8 | 1,388
Tdark 5 | 6,593
Tclin 3 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
abnormal bone structure 3 | 187
abnormal sleep behavior 3 | 70
decreased bone mineral content 3 | 151
decreased bone mineral density 3 | 126
decreased prepulse inhibition 3 | 82
decreased fasted circulating g... 2 | 65
increased body length 2 | 32
increased circulating alkaline... 2 | 122
abnormal behavior 1 | 298
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal epididymis morphology 1 | 42
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal incisor color 1 | 3
abnormal iris morphology 1 | 13
abnormal iris transilluminatio... 1 | 2
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
cataract 1 | 92
cystolithiasis 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating chloride... 1 | 30
decreased circulating glucose ... 1 | 126
decreased exploration in new e... 1 | 11
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
decreased urine creatinine lev... 1 | 3
enlarged epididymis 1 | 31
enlarged kidney 1 | 14
enlarged spleen 1 | 41
enlarged thymus 1 | 5
enlarged urinary bladder 1 | 8
eyelids fail to open 1 | 3
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
kyphosis 1 | 5
polycystic kidney 1 | 15
preweaning lethality, complete... 1 | 979
prolonged QRS complex duration 1 | 8
small kidney 1 | 16
small spleen 1 | 19

Disease

Carcinoma 87 | 11,493
atypical teratoid / rhabdoid tumor 44 | 5,112
glioblastoma 43 | 5,792
osteosarcoma 42 | 7,950
medulloblastoma, large-cell 41 | 6,241
ovarian cancer 40 | 8,520
ependymoma 39 | 4,679
psoriasis 35 | 6,694
group 3 medulloblastoma 28 | 4,104
lung cancer 27 | 4,740
adult high grade glioma 25 | 3,801
primitive neuroectodermal tumor 25 | 3,035
Astrocytoma, Pilocytic 23 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
oligodendroglioma 23 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 22 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
pituitary cancer 22 | 1,972
Kidney cancer 21 | 2,613
lung carcinoma 21 | 2,843
malignant mesothelioma 21 | 3,232
pancreatic cancer 20 | 2,398
Autosomal recessive predisposition 19 | 1,442
Breast cancer 19 | 3,578
Epilepsy 19 | 792
astrocytic glioma 19 | 2,597
invasive ductal carcinoma 19 | 2,951
cystic fibrosis 17 | 1,696
non-small cell lung cancer 17 | 2,890
tuberculosis 17 | 2,010
Schizophrenia 16 | 1,160
subependymal giant cell astrocytoma 16 | 2,287
Pick disease 15 | 1,894
active ulcerative colitis 15 | 764
colon cancer 15 | 1,478
ductal carcinoma in situ 15 | 1,745
Metabolic acidosis 13 | 90
lung adenocarcinoma 13 | 2,716
ulcerative colitis 13 | 1,819
Cancer 12 | 2,499
Seizures 12 | 596
active Crohn's disease 12 | 922
group 4 medulloblastoma 12 | 1,855
interstitial cystitis 12 | 2,312
Intellectual disability 11 | 1,016
pancreatic ductal adenocarcinoma liver metastasis 11 | 1,962
Pendred Syndrome 10 | 22
Lysinuric protein intolerance 9 | 15
non primary Sjogren syndrome sicca 9 | 891
pediatric high grade glioma 9 | 1,064
Bipolar Disorder 8 | 666
Cognitive delay 8 | 608
Cystinuria 8 | 18
Diastrophic dysplasia 8 | 21
Dull intelligence 8 | 645
Global developmental delay 8 | 608
Hypertension 8 | 396
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Muscle hypotonia 8 | 571
Poor school performance 8 | 645
astrocytoma 8 | 1,146
cutaneous lupus erythematosus 8 | 1,057
primary pancreatic ductal adenocarcinoma 8 | 1,109
Diarrhea 7 | 253
Edema 7 | 81
Failure to gain weight 7 | 365
Hartnup disease 7 | 13
Liver Cirrhosis, Experimental 7 | 769
Melanoma 7 | 711
Nephrolithiasis 7 | 56
Pediatric failure to thrive 7 | 365
Rheumatoid arthritis 7 | 1,191
Short stature 7 | 531
breast carcinoma 7 | 1,638
gastric carcinoma 7 | 807
nephrosclerosis 7 | 333
Alzheimer's disease 6 | 658
Autistic Disorder 6 | 364
Endometriosis 6 | 540
Growth delay 6 | 114
Growth failure 6 | 114
Growth retardation 6 | 115
Poor growth 6 | 114
Renal tubular acidosis 6 | 24
Very poor growth 6 | 114
atypical teratoid/rhabdoid tumor 6 | 357
Amyotrophic lateral sclerosis 5 | 451
Atopic dermatitis 5 | 952
Brain Ischemia 5 | 110
Kidney disease 5 | 430
Multiple myeloma 5 | 1,332
acute quadriplegic myopathy 5 | 1,158
aldosterone-producing adenoma 5 | 665
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
spina bifida 5 | 1,074

Tissue

Endocrine System 102 | 18,159
Urinary Tract 102 | 16,678
Nervous System 100 | 16,725
Liver and Pancreas 99 | 16,750
Male tissues 99 | 17,142
Digestive Tract 98 | 17,369
Female tissues 98 | 17,400
Blood and immune system 97 | 16,909
Skin and soft tissues 97 | 17,230
Respiratory system 93 | 16,393
Cardiovascular System 79 | 15,192

Target Family

Transporter 100 | 473
Ion Channel 2 | 344
Non-IDG 2 | 12,091

Reactome Pathway

Transport of inorganic cations... 104 | 104
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sialin SLC17A5 Tbio Transporter -2.93541 845.6 63
Proton-coupled amino acid transporter 4 SLC36A4 Tbio Transporter -1.46987 30.6 45
Sodium/hydrogen exchanger 5 SLC9A5 Tbio Transporter -1.15040 17.1 43
High affinity cationic amino acid transporter 1 SLC7A1 Tbio Transporter -2.71485 501.4 143
Vesicular glutamate transporter 3 SLC17A8 Tbio Transporter -2.00898 110.3 57
Y+L amino acid transporter 1 SLC7A7 Tbio Transporter -1.73334 56.0 46
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Large neutral amino acids transporter small subunit 2 SLC7A8 Tbio Transporter -1.20076 18.8 126
Sodium-dependent phosphate transporter 1 SLC20A1 Tbio Transporter -1.79308 59.6 101
Solute carrier family 12 member 7 SLC12A7 Tbio Transporter -1.46102 28.2 156