Development Level

Tbio 49 | 11,445
Tchem 23 | 1,598
Tclin 8 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 3 | 114
embryonic lethality prior to t... 3 | 278
abnormal bone structure 2 | 187
decreased total body fat amoun... 2 | 207
embryonic lethality prior to o... 2 | 239
abnormal coat appearance 1 | 31
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal hair growth 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain development 1 | 16
abnormal hindbrain morphology 1 | 10
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal sleep behavior 1 | 70
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating creatine... 1 | 4
decreased circulating iron lev... 1 | 32
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating creatine... 1 | 5
increased circulating creatini... 1 | 38
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
long tibia 1 | 25
short tibia 1 | 97
small heart 1 | 10
thrombocytosis 1 | 27

Disease

Carcinoma 72 | 11,493
ovarian cancer 41 | 8,520
medulloblastoma, large-cell 39 | 6,241
osteosarcoma 39 | 7,950
psoriasis 34 | 6,694
glioblastoma 33 | 5,792
ependymoma 28 | 4,679
atypical teratoid / rhabdoid tumor 24 | 5,112
group 3 medulloblastoma 23 | 4,104
pancreatic cancer 23 | 2,398
lung cancer 22 | 4,740
non-small cell lung cancer 20 | 2,890
adult high grade glioma 18 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
lung carcinoma 18 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
Astrocytoma, Pilocytic 16 | 3,081
lung adenocarcinoma 16 | 2,716
Breast cancer 15 | 3,578
active Crohn's disease 15 | 922
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
oligodendroglioma 15 | 2,850
tuberculosis 15 | 2,010
Schizophrenia 14 | 1,160
colon cancer 14 | 1,478
cystic fibrosis 14 | 1,696
invasive ductal carcinoma 14 | 2,951
malignant mesothelioma 13 | 3,232
primitive neuroectodermal tumor 13 | 3,035
Autosomal recessive predisposition 12 | 1,442
astrocytic glioma 12 | 2,597
Pick disease 11 | 1,894
nasopharyngeal carcinoma 11 | 1,058
ulcerative colitis 11 | 1,819
active ulcerative colitis 10 | 764
adrenocortical carcinoma 10 | 1,428
nephrosclerosis 10 | 333
pediatric high grade glioma 10 | 1,064
pituitary cancer 10 | 1,972
subependymal giant cell astrocytoma 10 | 2,287
Acrodermatitis enteropathica 9 | 18
Bipolar Disorder 9 | 666
Obesity 9 | 678
Rheumatoid arthritis 9 | 1,191
diabetes mellitus 9 | 1,728
Alzheimer's disease 8 | 658
Cancer 8 | 2,499
acute quadriplegic myopathy 8 | 1,158
ductal carcinoma in situ 8 | 1,745
esophageal adenocarcinoma 8 | 737
primary pancreatic ductal adenocarcinoma 8 | 1,109
Acquired metabolic disease 7 | 336
Alcoholic Intoxication, Chronic 7 | 289
Kidney cancer 7 | 2,613
Parkinson's disease 7 | 392
breast carcinoma 7 | 1,638
group 4 medulloblastoma 7 | 1,855
Atopic dermatitis 6 | 952
Depressive disorder 6 | 409
Down syndrome 6 | 499
Endometriosis 6 | 540
Epilepsy 6 | 792
cutaneous lupus erythematosus 6 | 1,057
juvenile dermatomyositis 6 | 1,187
pancreatic carcinoma 6 | 562
Anemia 5 | 365
Duchenne muscular dystrophy 5 | 601
Gingivitis 5 | 29
Gout 5 | 106
Hemochromatosis 5 | 54
Kidney disease 5 | 430
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Mental Depression 5 | 333
Mouth Infection Prevention 5 | 5
Neurodegenerative disease 5 | 414
Systemic primary carnitine deficiency disease 5 | 15
Tremor 5 | 113
astrocytoma 5 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
gastric cancer 5 | 459
gastric carcinoma 5 | 807
Arthritis, Rheumatoid 4 | 174
Attention deficit hyperactivity disorder 4 | 278
Dysarthria 4 | 192
Dystonia 4 | 164
Glaucoma 4 | 239
Hepatomegaly 4 | 285
Liver Cirrhosis 4 | 181
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
Unipolar Depression 4 | 250
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
head and neck cancer 4 | 271
mucosa-associated lymphoid tissue lymphoma 4 | 484
progressive supranuclear palsy 4 | 676
spina bifida 4 | 1,074

Tissue

Digestive Tract 81 | 17,369
Endocrine System 80 | 18,159
Skin and soft tissues 77 | 17,230
Urinary Tract 77 | 16,678
Female tissues 76 | 17,400
Male tissues 76 | 17,142
Nervous System 76 | 16,725
Blood and immune system 73 | 16,909
Liver and Pancreas 73 | 16,750
Respiratory system 66 | 16,393
Cardiovascular System 59 | 15,192

Target Family

Transporter 77 | 473
Non-IDG 7 | 12,091
Transcription Factor 1 | 1,400

Reactome Pathway

Transport of bile salts and or... 85 | 85
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc transporter 1 SLC30A1 Tbio Transporter -2.12639 135.9 148
Solute carrier family 22 member 7 SLC22A7 Tbio Transporter -2.14673 131.0 76
Sodium-dependent proline transporter SLC6A7 Tchem Transporter -2.10260 134.1 45
Solute carrier family 13 member 4 SLC13A4 Tbio Transporter -1.55886 37.5 50
Solute carrier family 13 member 3 SLC13A3 Tbio Transporter -1.47363 31.7 92
Choline transporter-like protein 1 SLC44A1 Tbio Transporter -1.60796 43.9 212
Zinc transporter ZIP10 SLC39A10 Tbio Transporter -1.20558 16.3 102
Zinc transporter ZIP6 SLC39A6 Tbio Transporter -1.66663 50.0 172
Zinc transporter 3 SLC30A3 Tbio Transporter -2.01559 111.7 67
Hephaestin HEPH Tbio Non-IDG -2.02535 102.7 111