Development Level

Tbio 74 | 11,445
Tdark 6 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 16 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal embryo size 2 | 220
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
abnormal behavior 1 | 298
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
cataract 1 | 92
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 34
decreased fasted circulating g... 1 | 65
decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
edema 1 | 59
enlarged heart 1 | 210
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 62 | 11,493
ovarian cancer 52 | 8,520
group 3 medulloblastoma 40 | 4,104
osteosarcoma 40 | 7,950
lung cancer 39 | 4,740
medulloblastoma, large-cell 36 | 6,241
glioblastoma 26 | 5,792
atypical teratoid / rhabdoid tumor 22 | 5,112
psoriasis 22 | 6,694
Breast cancer 20 | 3,578
primitive neuroectodermal tumor 18 | 3,035
Kidney cancer 17 | 2,613
ependymoma 17 | 4,679
malignant mesothelioma 17 | 3,232
Multiple myeloma 16 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,989
non-small cell lung cancer 15 | 2,890
acute quadriplegic myopathy 14 | 1,158
oligodendroglioma 14 | 2,850
Waldenstrons macroglobulinemia 13 | 765
astrocytic glioma 13 | 2,597
dermatomyositis 13 | 966
adult high grade glioma 12 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
Pick disease 10 | 1,894
invasive ductal carcinoma 10 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
astrocytoma 9 | 1,146
lung adenocarcinoma 8 | 2,716
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,499
colon cancer 7 | 1,478
Astrocytoma, Pilocytic 6 | 3,081
breast carcinoma 6 | 1,638
group 4 medulloblastoma 6 | 1,855
pancreatic cancer 6 | 2,398
progressive supranuclear palsy 6 | 676
tuberculosis and treatment for 6 months 6 | 409
Amyotrophic lateral sclerosis 5 | 451
Autosomal recessive predisposition 5 | 1,442
Gaucher disease type 1 5 | 180
HIV Infections 5 | 102
Intellectual disability 5 | 1,016
acute myeloid leukemia 5 | 783
adrenocortical carcinoma 5 | 1,428
diabetes mellitus 5 | 1,728
nasopharyngeal carcinoma 5 | 1,058
pediatric high grade glioma 5 | 1,064
tuberculosis 5 | 2,010
Atopic dermatitis 4 | 952
aldosterone-producing adenoma 4 | 665
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
posterior fossa group B ependymoma 4 | 416
spina bifida 4 | 1,074
Hematologic cancer 3 | 12
Immune system cancer 3 | 140
Leukemia 3 | 104
Microcephaly 3 | 166
Rheumatoid arthritis 3 | 1,191
interstitial cystitis 3 | 2,312
primary pancreatic ductal adenocarcinoma 3 | 1,109
sonic hedgehog group medulloblastoma 3 | 467
ulcerative colitis 3 | 1,819
Acquired immunodeficiency syndrome 2 | 197
Anemia 2 | 365
Autistic Disorder 2 | 364
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Curvature of little finger 2 | 110
Disease Progression 2 | 136
Dull intelligence 2 | 645
Endometrial cancer 2 | 311
Hypoplastic mandible condyle 2 | 275
Influenza 2 | 142
Leukemia, Myelocytic, Acute 2 | 120
Liver cancer 2 | 604
Low intelligence 2 | 645
Low-set, posteriorly rotated ears 2 | 110
MYELODYSPLASTIC SYNDROME 2 | 53
Mastocytosis 2 | 27
Mental deficiency 2 | 645
Polycystic ovary syndrome 2 | 360
Polycythemia vera 2 | 27
Poor school performance 2 | 645
Schizophrenia 2 | 1,160
Short stature 2 | 531
Stomach Neoplasms 2 | 300
Weight Gain 2 | 100
atypical teratoid/rhabdoid tumor 2 | 357
ductal carcinoma in situ 2 | 1,745
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
interstitial lung disease 2 | 298
lung carcinoma 2 | 2,843
pituitary cancer 2 | 1,972
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 80 | 18,159
Blood and immune system 79 | 16,909
Cardiovascular System 79 | 15,192
Digestive Tract 79 | 17,369
Female tissues 79 | 17,400
Liver and Pancreas 79 | 16,750
Male tissues 79 | 17,142
Nervous System 79 | 16,725
Respiratory system 79 | 16,393
Skin and soft tissues 79 | 17,230
Urinary Tract 79 | 16,678

Target Family

Non-IDG 75 | 12,091
Enzyme 6 | 4,145

Reactome Pathway

Transport of Mature Transcript... 81 | 81
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NTF2-related export protein 1 NXT1 Tbio Non-IDG -1.49831 29.4 91
RNA-binding protein 8A RBM8A Tbio Non-IDG -3.16448 1415.1 94
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
THO complex subunit 7 homolog THOC7 Tbio Non-IDG -0.34772 2.04 61
THO complex subunit 5 homolog THOC5 Tbio Non-IDG -1.14189 16.8 116
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Splicing factor U2AF 26 kDa subunit U2AF1L4 Tbio Non-IDG -0.17609 1.86 61
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Splicing factor U2AF 35 kDa subunit-like protein U2AF1 Tbio Non-IDG -1.71712 73.6 0