Development Level

Tbio 14 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pharyngeal arch morph... 1 | 8
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92

Disease

ovarian cancer 12 | 8,520
Carcinoma 8 | 11,493
group 3 medulloblastoma 8 | 4,104
lung cancer 8 | 4,740
osteosarcoma 8 | 7,950
malignant mesothelioma 6 | 3,232
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
non-small cell lung cancer 5 | 2,890
psoriasis 5 | 6,694
Breast cancer 4 | 3,578
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 783
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
atypical teratoid / rhabdoid tumor 4 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
nasopharyngeal carcinoma 4 | 1,058
primitive neuroectodermal tumor 4 | 3,035
Cancer 3 | 2,499
Multiple myeloma 3 | 1,332
Xeroderma pigmentosum 3 | 43
progressive supranuclear palsy 3 | 676
Abnormality of pelvic girdle bone morphology 2 | 37
Alzheimer's disease 2 | 658
Anemia 2 | 365
Anxiety 2 | 136
Anxiety disease 2 | 113
Arthralgia 2 | 90
Autosomal recessive predisposition 2 | 1,442
Chronic Lymphocytic Leukemia 2 | 262
Colonic Neoplasms 2 | 142
Congenital pes cavus 2 | 88
Creatine phosphokinase serum increased 2 | 110
Depressive disorder 2 | 409
Dysarthria 2 | 192
Dysgraphia 2 | 20
Elevated creatine kinase 2 | 110
Gait imbalance 2 | 17
Hypoplastic mandible condyle 2 | 275
Lung Neoplasms 2 | 232
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Muscle Spasticity 2 | 195
Muscle Weakness 2 | 170
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Nerve Degeneration 2 | 121
Neuro-degenerative disease 2 | 43
Neurodegenerative Disorders 2 | 79
Neurodegenerative disease 2 | 414
Photodysphoria 2 | 121
Photophobia 2 | 121
Photosensitivity of skin 2 | 51
Pick's disease 2 | 15
Progeria 2 | 25
Short stature 2 | 531
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Apraxias 1 | 27
Ataxia telangiectasia 1 | 34
Atrophic condition of skin 1 | 25
Back Pain 1 | 7
Brain Neoplasms 1 | 33
Cleft uvula 1 | 27
Congenital myasthenic syndrome 6 1 | 17
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Decreased width of tooth 1 | 59
Defective tooth enamel 1 | 31
Ectropion 1 | 38
Excess nuchal skin 1 | 30
Gait, Unsteady 1 | 29
Hepatoblastoma 1 | 19
Irritation - emotion 1 | 68
Ischemia 1 | 28
Lower limb hyperreflexia 1 | 10
Muscle Cramp 1 | 55
Neoplasms, Experimental 1 | 40
Poikiloderma 1 | 14
Poor speech 1 | 37
Problems speaking 1 | 37
Restlessness 1 | 14
Retinitis pigmentosa 12 1 | 9
Rimmed vacuoles on biopsy 1 | 15
Scapular weakness 1 | 23
Shoulder girdle muscle atrophy 1 | 6
Spider Veins 1 | 17
Submucous cleft of hard palate 1 | 11
Winged scapula 1 | 23

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 15 | 12,091
Enzyme 2 | 4,145

Reactome Pathway

Translesion Synthesis by POLH 17 | 17
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Replication factor C subunit 2 RFC2 Tbio Non-IDG -1.36589 20.3 293
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.43459 26.5 198
Replication factor C subunit 3 RFC3 Tbio Non-IDG -1.30866 19.7 176
Replication protein A 14 kDa subunit RPA3 Tbio Non-IDG -1.85941 67.1 171
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Replication protein A 70 kDa DNA-binding subunit RPA1 Tchem Non-IDG -2.48277 297.9 350
RING finger and CHY zinc finger domain-containing protein 1 RCHY1 Tbio Non-IDG -2.47052 287.7 126