Development Level

Tbio 24 | 11,445
Tclin 5 | 613
Tchem 4 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

enlarged heart 3 | 210
preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal seminal vesicle morph... 2 | 114
small testis 2 | 58
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal joint morphology 1 | 23
abnormal lung morphology 1 | 26
abnormal optic disc morphology 1 | 10
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
brachydactyly 1 | 19
corneal opacity 1 | 32
decreased body length 1 | 101
decreased circulating alkaline... 1 | 46
decreased circulating insulin ... 1 | 76
decreased food intake 1 | 13
decreased heart weight 1 | 27
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
syndactyly 1 | 23

Disease

ovarian cancer 23 | 8,520
Cancer 22 | 2,499
Carcinoma 20 | 11,493
lung cancer 19 | 4,740
psoriasis 18 | 6,694
Breast cancer 17 | 3,578
medulloblastoma, large-cell 15 | 6,241
osteosarcoma 15 | 7,950
glioblastoma 14 | 5,792
group 3 medulloblastoma 13 | 4,104
non-small cell lung cancer 13 | 2,890
Kidney cancer 11 | 2,613
Stomach Neoplasms 11 | 300
ependymoma 11 | 4,679
atypical teratoid / rhabdoid tumor 10 | 5,112
ductal carcinoma in situ 10 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
invasive ductal carcinoma 10 | 2,951
malignant mesothelioma 10 | 3,232
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Breast Neoplasms 8 | 445
Prostatic Neoplasms 8 | 495
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung adenocarcinoma 8 | 2,716
oligodendroglioma 8 | 2,850
spina bifida 8 | 1,074
ulcerative colitis 8 | 1,819
Astrocytoma, Pilocytic 7 | 3,081
Mammary Neoplasms 7 | 425
pancreatic cancer 7 | 2,398
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
tuberculosis 7 | 2,010
Adenocarcinoma 6 | 122
Adenoma 6 | 167
Autosomal recessive predisposition 6 | 1,442
Bladder Neoplasm 6 | 112
Carcinoma, Squamous Cell 6 | 110
Colonic Neoplasms 6 | 142
Cryptorchidism 6 | 296
Disease Progression 6 | 136
Neoplasm Metastasis 6 | 168
Obesity 6 | 678
Schizophrenia 6 | 1,160
Squamous cell carcinoma 6 | 129
Strabismus 6 | 270
Urinary Bladder Neoplasms 6 | 114
Waldenstrons macroglobulinemia 6 | 765
acute quadriplegic myopathy 6 | 1,158
breast carcinoma 6 | 1,638
primitive neuroectodermal tumor 6 | 3,035
Adenocarcinoma of lung 5 | 142
Bilateral fifth finger clinodactyly 5 | 110
Bipolar Disorder 5 | 666
Carcinoma, Non-Small-Cell Lung 5 | 107
Craniofacial Abnormalities 5 | 151
Curvature of little finger 5 | 110
Decreased projection of maxilla 5 | 66
Deficiency of upper jaw bones 5 | 66
Disease Models, Animal 5 | 155
Epilepsy 5 | 792
Esophageal Squamous Cell Carcinoma 5 | 77
Heart disease 5 | 306
Hypoplasia of the maxilla 5 | 66
Hypoplastic mandible condyle 5 | 275
Hypotrophic maxilla 5 | 66
Immune system cancer 5 | 140
Lung Neoplasms 5 | 232
Lymphoid leukemia 5 | 160
Mammary Neoplasms, Animal 5 | 136
Mammary Neoplasms, Experimental 5 | 154
Mandibular hypoplasia 5 | 275
Maxillary retrognathia 5 | 66
Micrognathism 5 | 275
Multiple myeloma 5 | 1,332
Neoplasm Recurrence, Local 5 | 37
Neurodegenerative disease 5 | 414
Penile hypospadias 5 | 106
Retrusion of upper jaw bones 5 | 66
Seizures 5 | 596
Squamous cell carcinoma of esophagus 5 | 77
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
cutaneous lupus erythematosus 5 | 1,057
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
lung carcinoma 5 | 2,843
non-small cell lung carcinoma 5 | 317
Broad flat nasal bridge 4 | 236
Carcinoma, Hepatocellular 4 | 228
Glaucoma 4 | 239
Liver carcinoma 4 | 240
Nasal bridge wide 4 | 236
acute myeloid leukemia 4 | 783
atypical teratoid/rhabdoid tumor 4 | 357
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Cardiovascular System 33 | 15,192
Digestive Tract 33 | 17,369
Endocrine System 33 | 18,159
Female tissues 33 | 17,400
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Blood and immune system 32 | 16,909
Liver and Pancreas 32 | 16,750
Respiratory system 32 | 16,393

Target Family

Non-IDG 14 | 12,091
Transcription Factor 9 | 1,400
Enzyme 3 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

Reactome Pathway

Transcriptional regulation by ... 34 | 34
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.62079 405.6 915
Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase NOP2 Tbio Enzyme -1.50027 29.5 69
BTB/POZ domain-containing protein KCTD1 KCTD1 Tbio Non-IDG -2.27376 183.1 83
Protein DEK DEK Tbio Non-IDG -2.24912 193.2 183
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Transcription factor AP-2-delta TFAP2D Tdark Transcription Factor -0.37805 1.66 118
Myb-related protein B MYBL2 Tbio Transcription Factor -2.19738 169.0 289
Transcription factor AP-2-epsilon TFAP2E Tbio Transcription Factor -1.07474 11.3 37
Transcription factor AP-2 gamma TFAP2C Tbio Transcription Factor -1.88406 72.7 269