Development Level

Tbio 3 | 10,625
Tchem 1 | 1,890

IMPC Term

abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal spleen morphology 1 | 36
abnormal testis morphology 1 | 30
decreased circulating insulin ... 1 | 75
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged spleen 1 | 26
small testis 1 | 37

Disease

lung cancer 3 | 4,466
medulloblastoma, large-cell 3 | 6,234
Adenoma 2 | 165
Bladder Neoplasm 2 | 109
Cancer 2 | 2,346
Carcinoma, Transitional Cell 2 | 31
Colonic Neoplasms 2 | 126
Lung Neoplasms 2 | 171
Papilloma 2 | 27
Prostatic Neoplasms 2 | 471
Rheumatoid Arthritis 2 | 1,160
Squamous cell carcinoma of esophagus 2 | 82
Stomach Neoplasms 2 | 282
astrocytoma 2 | 1,493
ductal carcinoma in situ 2 | 1,745
group 3 medulloblastoma 2 | 2,254
malignant mesothelioma 2 | 3,162
oligodendroglioma 2 | 2,849
osteosarcoma 2 | 7,933
ovarian cancer 2 | 8,484
psoriasis 2 | 6,685
subependymal giant cell astrocytoma 2 | 2,287
ADRENOCORTICAL CARCINOMA, HEREDITARY 1 | 1
Acquired immunodeficiency syndrome 1 | 164
Acute Megakaryocytic Leukemias 1 | 4
Adenocarcinoma 1 | 115
Adenocarcinoma Of Esophagus 1 | 14
Adenocarcinoma, Clear Cell 1 | 2
Adrenal Gland Neoplasms 1 | 11
Adrenocortical Carcinoma, Pediatric 1 | 1
Anaplastic thyroid carcinoma 1 | 2
Balkan Nephropathy 1 | 6
Barrett's esophagus 1 | 183
Basal cell carcinoma 1 | 29
Brain disease 1 | 83
Breast adenocarcinoma 1 | 8
Carcinoma, Small Cell 1 | 8
Carotid Artery Diseases 1 | 11
Central Nervous System Neoplasms 1 | 1
Cervix carcinoma 1 | 6
Cervix uteri carcinoma in situ 1 | 14
Choroid Plexus Carcinoma 1 | 4
Choroid Plexus Papilloma 1 | 10
Chronic Obstructive Airway Disease 1 | 47
DOID:2627 1 | 14
Demyelinating Diseases 1 | 7
Diabetes Mellitus, Experimental 1 | 106
Endometrial cancer 1 | 25
Epidermodysplasia verruciformis 1 | 21
Epithelial ovarian cancer 1 | 19
Esophageal Neoplasms 1 | 67
Familial adenomatous polyposis 1 | 31
GLIOMA SUSCEPTIBILITY 1 1 | 3
Gastritis 1 | 44
Genitourinary Neoplasms 1 | 3
Glioma 1 | 65
Hemangioma 1 | 35
Hemangiosarcoma 1 | 18
Hepatoblastoma 1 | 17
Hereditary Breast and Ovarian Cancer Syndrome 1 | 14
Hypertrophic Cardiomyopathy 1 | 56
Intestinal Neoplasms 1 | 11
Ischemia 1 | 27
Keratosis 1 | 34
LI-FRAUMENI SYNDROME 1 1 | 2
Large intestine cancer 1 | 12
Leukemia, Megakaryoblastic, of Down Syndrome 1 | 9
Li-Fraumeni Syndrome 1 | 13
Li-Fraumeni Syndrome 2 1 | 2
Li-Fraumeni-Like Syndrome 1 | 1
Liver Diseases, Parasitic 1 | 9
Liver Neoplasms, Experimental 1 | 48
Lymphoid leukemia 1 | 69
Lymphoma, T-Cell, Cutaneous 1 | 21
Lynch syndrome 1 | 33
Mediastinal Germ Cell Tumor 1 | 2
Mouth Neoplasms 1 | 42
Neoplastic Cell Transformation 1 | 81
Neurofibromatosis 1 | 37
Nijmegen breakage syndrome 1 | 23
Pancreatitis 1 | 97
Pathological accumulation of air in tissues 1 | 11
Penile Neoplasms 1 | 4
Pleomorphic adenoma 1 | 18
Progressive multifocal leukoencephalopathy 1 | 24
Renal Cell Carcinoma 1 | 199
Sarcoma 1 | 49
Sezary Syndrome 1 | 26
Skin Neoplasms 1 | 49
Skin cancer 1 | 37
Skin disease 1 | 65
Small cell carcinoma of lung 1 | 45
Squamous cell carcinoma of the head and neck 1 | 24
T-Cell Lymphoma 1 | 11
Thymoma 1 | 16
Thyroid Neoplasm 1 | 33
Urologic Neoplasms 1 | 7
Vulvar Lichen Sclerosus 1 | 2
Xeroderma pigmentosum 1 | 41
gallbladder neoplasm 1 | 9

Tissue

Blood and immune system 4 | 17,995
Cardiovascular System 4 | 17,958
Digestive Tract 4 | 18,473
Endocrine System 4 | 18,512
Female tissues 4 | 18,647
Liver and Pancreas 4 | 18,136
Male tissues 4 | 17,969
Nervous System 4 | 18,561
Respiratory system 4 | 17,484
Skin and soft tissues 4 | 18,115
Urinary Tract 4 | 18,444

Target Family

Non-IDG 2 | 11,971
Enzyme 1 | 4,146
Transcription Factor 1 | 1,400

Reactome Pathway

Transcriptional activation of ... 4 | 4
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177
Zinc finger protein 385A ZNF385A Tbio Non-IDG 0.15 0.99 87
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.67490 51004.8 5255
Poly(rC)-binding protein 4 PCBP4 Tbio Non-IDG -1.32082 22.9 119