Development Level

Tbio 11 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal lens morphology 1 | 81
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 10 | 8,520
Cancer 9 | 2,499
Carcinoma 9 | 11,493
group 3 medulloblastoma 8 | 4,104
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
Breast cancer 5 | 3,578
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Retinoblastoma 4 | 19
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
Kidney cancer 3 | 2,613
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
tuberculosis 3 | 2,010
Atopic dermatitis 2 | 952
Endometriosis 2 | 540
Liver Cirrhosis, Experimental 2 | 769
Pick disease 2 | 1,894
Pleural empyema 2 | 12
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
primary Sjogren syndrome 2 | 735
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Arthritis, Juvenile 1 | 126
Breast Neoplasms 1 | 445
Carcinoma, Hepatocellular 1 | 228
Carcinoma, Squamous Cell 1 | 110
Cardiovascular system disease 1 | 246
Central pontine myelinolysis 1 | 5
Chronic Lymphocytic Leukemia 1 | 262
Complex regional pain syndrome 1 | 12
Dental fluorosis 1 | 20
Diffuse large B-cell lymphoma 1 | 39
Drug-induced paranoid state 1 | 5
Familial primary pulmonary hypertension 1 | 11
Heart Diseases 1 | 43
Hemoglobin E disease 1 | 3
Juvenile arthritis 1 | 126
Kidney disease 1 | 430
Leukemia, Lymphocytic, Chronic, B-Cell 1 | 34
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Lymphoma, Large B-Cell, Diffuse 1 | 34
Mammary Neoplasms 1 | 425
Melanoma 1 | 711
Mesothelioma, Malignant 1 | 105
Mood Disorders 1 | 184
Multiple myeloma 1 | 1,332
Neuronal ceroid lipofuscinosis 1 | 28
Ovarian Neoplasms 1 | 102
Peripheral T-cell lymphoma 1 | 25
Primary cutaneous T-cell lymphoma 1 | 29
Rheumatoid arthritis 1 | 1,191
Schizophrenia 1 | 1,160
Squamous cell carcinoma 1 | 129
Tuberculous peritonitis 1 | 2
Type 2 diabetes mellitus 1 | 272
Xeroderma pigmentosum group E 1 | 3
active Crohn's disease 1 | 922
astrocytic glioma 1 | 2,597
breast carcinoma 1 | 1,638
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
interstitial cystitis 1 | 2,312
lung carcinoma 1 | 2,843
nasopharyngeal carcinoma 1 | 1,058
ovarian neoplasm 1 | 99
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064

Tissue

Blood and immune system 15 | 16,909
Cardiovascular System 15 | 15,192
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678

Target Family

Non-IDG 7 | 12,091
Transcription Factor 6 | 1,400
Epigenetic 1 | 242
Kinase 1 | 634

Reactome Pathway

Transcription of E2F targets u... 15 | 15
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myb-related protein B MYBL2 Tbio Transcription Factor -2.19738 169.0 289
Protein lin-52 homolog LIN52 Tbio Non-IDG -0.97901 7.87 61
Protein lin-54 homolog LIN54 Tdark Non-IDG -1.29119 19.5 45
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
Retinoblastoma-like protein 1 RBL1 Tbio Non-IDG -2.62435 385.9 321
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.71209 53.9 310
Protein lin-9 homolog LIN9 Tbio Non-IDG -1.92491 83.2 101
Retinoblastoma-like protein 2 RBL2 Tbio Non-IDG -2.71244 526.8 359
Transcription factor E2F4 E2F4 Tbio Transcription Factor -2.31831 191.7 319
Transcription factor Dp-2 TFDP2 Tbio Transcription Factor -0.71407 4.94 153