Development Level

Tbio 8 | 11,445
Tclin 4 | 613
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
increased circulating free fat... 1 | 20
small superior vagus ganglion 1 | 74

Disease

Carcinoma 13 | 11,493
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 10 | 5,112
medulloblastoma, large-cell 10 | 6,241
ovarian cancer 9 | 8,520
Schizophrenia 8 | 1,160
adult high grade glioma 8 | 3,801
ependymoma 8 | 4,679
psoriasis 8 | 6,694
group 3 medulloblastoma 7 | 4,104
lung carcinoma 7 | 2,843
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
Kidney cancer 6 | 2,613
Pick disease 6 | 1,894
Astrocytoma, Pilocytic 5 | 3,081
Intellectual disability 5 | 1,016
Major Depressive Disorder 5 | 301
lung cancer 5 | 4,740
Bipolar Disorder 4 | 666
Breast cancer 4 | 3,578
Epilepsy 4 | 792
Epilepsy characterized by intractable complex partial seizures 4 | 28
General anesthesia 4 | 53
Lennox-Gastaut syndrome 4 | 34
Local anesthesia 4 | 40
Migraine Prevention 4 | 23
Partial seizure 4 | 15
Simple partial seizure 4 | 26
Tonic-clonic epilepsy 4 | 47
astrocytic glioma 4 | 2,597
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
osteosarcoma 4 | 7,950
subependymal giant cell astrocytoma 4 | 2,287
Cataract 8 multiple types 3 | 33
Depressive disorder 3 | 409
Dull intelligence 3 | 645
Liver cancer 3 | 604
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Unipolar Depression 3 | 250
astrocytoma 3 | 1,146
gastric carcinoma 3 | 807
non-small cell lung cancer 3 | 2,890
Alzheimer's disease 2 | 658
Amyotrophic lateral sclerosis 2 | 451
Autistic Disorder 2 | 364
Cardiomegaly 2 | 116
Cocaine-Related Disorders 2 | 92
Heart disease 2 | 306
Hyperactive behavior 2 | 91
Hyperkinesis 2 | 32
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
Nonorganic psychosis 2 | 84
Parkinson's disease 2 | 392
Psychosexual Disorders 2 | 6
Psychotic Disorders 2 | 151
Rheumatoid arthritis 2 | 1,191
Schizoaffective Disorder 2 | 55
Sexual Dysfunctions, Psychological 2 | 6
Substance Withdrawal Syndrome 2 | 55
Tetanus 2 | 68
Toxic encephalopathy 2 | 141
Vascular disease 2 | 319
active ulcerative colitis 2 | 764
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Absent eyelashes 1 | 16
Actinic keratosis 1 | 21
Ambiguous Genitalia 1 | 24
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Aplasia of eyelashes 1 | 16
Bicornuate uterus 1 | 11
Calcium pyrophosphate deposition disease 1 | 13
Cerebellar Dysmetria 1 | 56
Choanal stenosis 1 | 11
Failure of development of eyelashes 1 | 16
Hyperglycemia 1 | 137
Hypoparathyroidism 1 | 41
Hypotension 1 | 82
Intestinal Neoplasms 1 | 12
Malocclusion 1 | 57
Mild Mental Retardation 1 | 70
Polyuria 1 | 23
Progressive cerebellar ataxia 1 | 13
Psychoses, Substance-Induced 1 | 17
Trigeminal Neuralgia 1 | 24

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Skin and soft tissues 15 | 17,230
Blood and immune system 14 | 16,909
Liver and Pancreas 14 | 16,750
Respiratory system 13 | 16,393
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 8 | 12,091
Ion Channel 4 | 344
Kinase 3 | 634
Enzyme 1 | 4,145

Reactome Pathway

Trafficking of GluR2-containin... 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Vesicle-fusing ATPase NSF Tbio Enzyme -2.93271 688.8 206
Glutamate receptor-interacting protein 2 GRIP2 Tdark Non-IDG 0.00000 0
AP-2 complex subunit beta AP2B1 Tbio Non-IDG -1.59767 34.8 212
AP-2 complex subunit alpha-2 AP2A2 Tbio Non-IDG -0.65996 4.74 124
Tetraspanin-7 TSPAN7 Tbio Non-IDG -1.92109 78.9 165
AP-2 complex subunit sigma AP2S1 Tbio Non-IDG -1.42073 25.5 108
Glutamate receptor 4 GRIA4 Tclin Ion Channel -2.43418 256.1 326