Development Level

Tchem 13 | 1,890
Tbio 9 | 10,625
Tclin 3 | 602

IMPC Term

limb grasping 2 | 35
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal locomotor activation 1 | 26
abnormal response to new envir... 1 | 8
corneal vascularization 1 | 5
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 24
decreased circulating glycerol... 1 | 19
decreased circulating triglyce... 1 | 83
decreased lean body mass 1 | 195
hyperactivity 1 | 108
preweaning lethality, complete... 1 | 633

Disease

Carcinoma 11 | 2,147
osteosarcoma 8 | 7,933
psoriasis 8 | 6,685
medulloblastoma, large-cell 7 | 6,234
ovarian cancer 7 | 8,484
Dentin sensitivity 6 | 14
glioblastoma 6 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung cancer 6 | 4,466
Hypertension 5 | 287
atypical teratoid/rhabdoid tumor 5 | 1,095
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
Cancer 4 | 2,346
Neuropathy 4 | 210
Pain 4 | 70
Pain agnosia 4 | 99
cutaneous lupus erythematosus 4 | 1,056
cystic fibrosis 4 | 1,665
lung adenocarcinoma 4 | 2,713
malignant mesothelioma 4 | 3,162
ulcerative colitis 4 | 2,087
Gangliosidosis 3 | 17
Hyperalgesia 3 | 71
Migraine 3 | 79
Neurodegenerative disease 3 | 383
Pick disease 3 | 1,893
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
invasive ductal carcinoma 3 | 2,950
lung carcinoma 3 | 2,844
sonic hedgehog group medulloblastoma 3 | 1,482
Allergic hypersensitivity disease 2 | 123
Arthritic Pain 2 | 5
Aspiration pneumonia 2 | 5
Asthma 2 | 349
Atopic dermatitis 2 | 944
Backache 2 | 8
Bipolar Disorder 2 | 266
Endometriosis 2 | 535
Headache disorder 2 | 20
Hypertensive disease 2 | 193
Hypervitaminosis D 2 | 8
Inflammation 2 | 109
Irritable bowel syndrome 2 | 59
Kidney disease 2 | 396
Pain disorder 2 | 13
Polycystic kidney disease 2 | 54
Prostate cancer 2 | 172
Rickets 2 | 42
Sprains and Strains 2 | 6
Vascular disease 2 | 281
active Crohn's disease 2 | 918
atypical teratoid / rhabdoid tumor 2 | 4,369
group 3 medulloblastoma 2 | 2,254
group 4 medulloblastoma 2 | 1,875
head and neck cancer 2 | 270
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
non-small cell lung carcinoma 2 | 413
pancreatic cancer 2 | 2,300
pediatric high grade glioma 2 | 2,712
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Amyotrophic Lateral Sclerosis, Guam Form 1 | 2
Autosomal dominant cerebellar ataxia 1 | 34
Bronchial Hyperreactivity 1 | 13
Cardiomegaly 1 | 66
Cerebellar Ataxia 1 | 72
Charcot-Marie-Tooth disease 1 | 74
Chronic Obstructive Airway Disease 1 | 47
Colonic Polyps 1 | 3
Common cold 1 | 63
Dyspepsia 1 | 34
Enamel caries 1 | 8
Esophagitis 1 | 26
Glycoproteinosis 1 | 13
Hypercalcemia 1 | 37
Hypoparathyroidism 1 | 29
Kidney Calculi 1 | 7
Liver Cirrhosis 1 | 101
Liver Cirrhosis, Experimental 1 | 108
Melanoma 1 | 261
Migraine Disorders 1 | 26
Ophthalmomyiasis 1 | 3
Osteochondrodysplasias 1 | 15
Palmoplantar keratosis 1 | 36
Pancreatitis 1 | 97
Paralysed 1 | 9
Pityriasis versicolor 1 | 18
Rhinitis 1 | 46
Right bundle branch block 1 | 12
Sneddon syndrome 1 | 4

Tissue

Blood and immune system 25 | 17,995
Cardiovascular System 25 | 17,958
Digestive Tract 25 | 18,473
Endocrine System 25 | 18,512
Female tissues 25 | 18,647
Liver and Pancreas 25 | 18,136
Male tissues 25 | 17,969
Nervous System 25 | 18,561
Skin and soft tissues 25 | 18,115
Urinary Tract 25 | 18,444
Respiratory system 24 | 17,484

Target Family

Ion Channel 23 | 341
Kinase 1 | 634
Non-IDG 1 | 11,971

Reactome Pathway

TRP channels 25 | 25
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucolipin-2 MCOLN2 Tbio Ion Channel -0.99717 10.3 31
Short transient receptor potential channel 5 TRPC5 Tchem Ion Channel -2.20004 159.7 209
Transient receptor potential cation channel subfamily M member 3 TRPM3 Tbio Ion Channel -2.09081 123.9 117
Short transient receptor potential channel 7 TRPC7 Tbio Ion Channel -2.43623 198.9 193
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.39774 268.0 184
Transient receptor potential cation channel subfamily M member 2 TRPM2 Tchem Ion Channel -1.24488 21.6 183
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.77781 670.1 248
Transient receptor potential cation channel subfamily M member 5 TRPM5 Tchem Ion Channel -1.89870 83.4 103
Transient receptor potential cation channel subfamily M member 6 TRPM6 Tchem Kinase -2.12808 138.4 95
Transient receptor potential cation channel subfamily M member 7 TRPM7 Tchem Ion Channel -2.45510 328.6 297