Development Level

Tbio 24 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased mean corpuscular vol... 1 | 79

Disease

Carcinoma 16 | 11,493
psoriasis 13 | 6,694
ovarian cancer 12 | 8,520
Cancer 11 | 2,499
juvenile dermatomyositis 10 | 1,187
Influenza 9 | 142
glioblastoma 9 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
osteosarcoma 8 | 7,950
Melanoma 7 | 711
Microphthalmia with limb anomalies 7 | 40
lung cancer 7 | 4,740
adult high grade glioma 6 | 3,801
cutaneous lupus erythematosus 6 | 1,057
ependymoma 6 | 4,679
Astrocytoma, Pilocytic 5 | 3,081
Hepatitis 5 | 67
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
Hepatitis C 4 | 94
Kidney cancer 4 | 2,613
Multiple Sclerosis 4 | 540
atypical teratoid / rhabdoid tumor 4 | 5,112
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Arthritis 3 | 290
Asthma 3 | 385
Bladder Neoplasm 3 | 112
Breast Neoplasms 3 | 445
Carcinoma, Transitional Cell 3 | 32
Encephalitis 3 | 64
Glaucoma 3 | 239
Hepatitis B 3 | 108
Hypersensitivity reaction type II disease 3 | 253
Influenza, Human 3 | 51
Major Depressive Disorder 3 | 301
Mammary Neoplasms 3 | 425
Renal Cell Carcinoma 3 | 214
Systemic lupus erythematosus 3 | 194
Urinary Bladder Neoplasms 3 | 114
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
primary Sjogren syndrome 3 | 735
Amyotrophic lateral sclerosis 2 | 451
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Carcinoma, Squamous Cell 2 | 110
Colorectal Neoplasms 2 | 243
Crohn's disease 2 | 321
Depressive disorder 2 | 409
Fatigue 2 | 182
Gaucher disease type 1 2 | 180
Hantavirus pulmonary syndrome 2 | 6
Hepatitis D 2 | 10
Herpes simplex 2 | 18
Human immunodeficiency virus infectious disease 2 | 138
Hyperreflexia 2 | 209
Immune system cancer 2 | 140
Immunologic Deficiency Syndromes 2 | 113
Inflammation 2 | 120
Leukopenia 2 | 72
Lymphoid leukemia 2 | 160
Lymphoma, Follicular 2 | 18
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Pain 2 | 103
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Pneumonia 2 | 174
Rheumatoid arthritis 2 | 1,191
SINGLETON-MERTEN SYNDROME 1 2 | 2
Seizures 2 | 596
Severe acute respiratory syndrome 2 | 27
Singleton-Merten dysplasia 2 | 2
Squamous cell carcinoma 2 | 129
Stevens-Johnson syndrome 2 | 92
Stomach Neoplasms 2 | 300
Unipolar Depression 2 | 250
Vascular disease 2 | 319
active Crohn's disease 2 | 922
acute myeloid leukemia 2 | 783
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
glioblastoma multiforme 2 | 142
group 4 medulloblastoma 2 | 1,855
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
invasive ductal carcinoma 2 | 2,951
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 20 | 16,909
Male tissues 19 | 17,142
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Non-IDG 18 | 12,091
Enzyme 5 | 4,145
Transcription Factor 4 | 1,400
Kinase 2 | 634
Epigenetic 1 | 242

Reactome Pathway

TRAF6 mediated IRF7 activation 30 | 30
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of IKBKE 1 SIKE1 Tdark Non-IDG -0.71713 4.66 97
Interferon alpha-17 IFNA17 Tbio Non-IDG -2.39299 231.1 56
ATP-dependent RNA helicase DHX36 DHX36 Tbio Enzyme -1.55120 37.4 112
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
TRAF family member-associated NF-kappa-B activator TANK Tbio Non-IDG -1.81992 67.5 373
Interferon alpha-6 IFNA6 Tbio Non-IDG -0.90731 7.40 134
Interferon alpha-16 IFNA16 Tdark Non-IDG -0.26324 1.39 73
Interferon-induced helicase C domain-containing protein 1 IFIH1 Tbio Enzyme -2.67869 455.3 335
Serine/threonine-protein kinase TBK1 TBK1 Tchem Kinase -2.76728 569.1 455
Interferon regulatory factor 2 IRF2 Tbio Transcription Factor -2.15319 132.7 378