Development Level

Tbio 9 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased circulating insulin ... 1 | 76
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
small seminal vesicle 1 | 10
small testis 1 | 58

Disease

medulloblastoma, large-cell 10 | 6,241
ovarian cancer 10 | 8,520
psoriasis 10 | 6,694
Cancer 9 | 2,499
glioblastoma 9 | 5,792
Carcinoma 8 | 11,493
group 3 medulloblastoma 8 | 4,104
Breast cancer 7 | 3,578
lung cancer 7 | 4,740
malignant mesothelioma 7 | 3,232
osteosarcoma 7 | 7,950
adult high grade glioma 6 | 3,801
atypical teratoid / rhabdoid tumor 6 | 5,112
ductal carcinoma in situ 6 | 1,745
ependymoma 6 | 4,679
non-small cell lung cancer 6 | 2,890
primitive neuroectodermal tumor 6 | 3,035
Carcinoma, Hepatocellular 5 | 228
Endometriosis 5 | 540
Liver carcinoma 5 | 240
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Atopic dermatitis 4 | 952
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
subependymal giant cell astrocytoma 4 | 2,287
Adenoma 3 | 167
Astrocytoma, Pilocytic 3 | 3,081
Bladder Neoplasm 3 | 112
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Mesothelioma, Malignant 3 | 105
Prostatic Neoplasms 3 | 495
Stomach Neoplasms 3 | 300
Urinary Bladder Neoplasms 3 | 114
breast carcinoma 3 | 1,638
nasopharyngeal carcinoma 3 | 1,058
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
Abdominal pain, episodic 2 | 9
Acromegaly 2 | 51
Adrenal cortical adenoma 2 | 19
Angiofibroma 2 | 7
Carcinoma, Transitional Cell 2 | 32
Carcinoma, squamous cell of head and neck 2 | 31
Colonic Neoplasms 2 | 142
Diarrhea 2 | 253
Esophageal Squamous Cell Carcinoma 2 | 77
Esophagitis 2 | 35
Growth hormone excess 2 | 14
Hypercalcemia 2 | 59
Hyperinsulinaemic hypoglycaemia 2 | 16
Hyperinsulinemia, fasting 2 | 7
Hyperparathyroidism 2 | 48
Increased serum parathyroid hormone 2 | 14
Insulinoma 2 | 24
Intestinal Neoplasms 2 | 12
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Liver neoplasms 2 | 130
Multiple Endocrine Neoplasia Type 1 2 | 29
Non-Functioning Pituitary Gland Neoplasm 2 | 6
Ovarian Neoplasms 2 | 102
Papilloma 2 | 44
Parathyroid Adenoma 2 | 19
Parathyroid hyperplasia 2 | 6
Peptic Ulcer 2 | 27
Pituitary adenoma 2 | 38
Pituitary growth hormone cell adenoma 2 | 8
Polycystic ovary syndrome 2 | 360
Prolactinoma 2 | 11
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Sezary Syndrome 2 | 27
Squamous cell carcinoma of esophagus 2 | 77
Squamous cell carcinoma of the head and neck 2 | 29
Subcutaneous lipomas 2 | 9
Thyroid Gland Follicular Adenoma 2 | 9
Urinary bladder cancer 2 | 36
Zollinger-Ellison syndrome 2 | 18
active Crohn's disease 2 | 922
astrocytic glioma 2 | 2,597
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
intermittent abdominal pain 2 | 9
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
medulloblastoma 2 | 720
ovarian neoplasm 2 | 99
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Adrenal Gland Neoplasms 1 | 11
Balkan Nephropathy 1 | 6
Carotid Artery Diseases 1 | 11
Malignant neoplasm of skin 1 | 15
Malignant tumor of colon 1 | 19
Tumors of Adrenal Cortex 1 | 3

Tissue

Blood and immune system 13 | 16,909
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678
Cardiovascular System 12 | 15,192

Target Family

Non-IDG 6 | 12,091
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145
Kinase 1 | 634

Reactome Pathway

TP53 Regulates Transcription o... 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 385A ZNF385A Tbio Non-IDG -0.03141 1.24 99
Cyclin-A1 CCNA1 Tbio Non-IDG -2.02564 107.2 314
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Transcription factor E2F8 E2F8 Tbio Transcription Factor -1.36831 22.7 147
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509
Cyclin-dependent kinase 2 CDK2 Tchem Kinase -3.44266 2522.8 1114
G1/S-specific cyclin-E1 CCNE1 Tchem Non-IDG -2.47823 262.4 894
Cyclin-A2 CCNA2 Tchem Non-IDG -2.33611 184.4 494
G1/S-specific cyclin-E2 CCNE2 Tbio Non-IDG -1.84118 53.8 225
Cyclin-dependent kinase inhibitor 1B CDKN1B Tbio Enzyme -3.11753 1246.6 1886