Development Level

Tbio 16 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

hyperactivity 3 | 148
decreased mean corpuscular vol... 2 | 79
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
abnormal behavior 1 | 298
preweaning lethality, incomple... 1 | 499

Disease

Cancer 12 | 2,499
ovarian cancer 12 | 8,520
osteosarcoma 11 | 7,950
medulloblastoma, large-cell 10 | 6,241
Carcinoma 9 | 11,493
lung cancer 9 | 4,740
Breast cancer 8 | 3,578
group 3 medulloblastoma 8 | 4,104
psoriasis 8 | 6,694
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
adult high grade glioma 6 | 3,801
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Breast Neoplasms 5 | 445
Kidney cancer 5 | 2,613
non primary Sjogren syndrome sicca 5 | 891
oligodendroglioma 5 | 2,850
Amyotrophic lateral sclerosis 4 | 451
Astrocytoma, Pilocytic 4 | 3,081
Carcinoma, Squamous Cell 4 | 110
Lymphoid leukemia 4 | 160
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
Skin cancer 4 | 469
Squamous cell carcinoma 4 | 129
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
hepatocellular carcinoma 4 | 547
primitive neuroectodermal tumor 4 | 3,035
Adenocarcinoma of lung (disorder) 3 | 60
Adenoid Cystic Carcinoma 3 | 99
Bipolar Disorder 3 | 666
Bladder Neoplasm 3 | 112
Carcinoma, Adenoid Cystic 3 | 99
Carcinoma, Hepatocellular 3 | 228
Chronic Lymphocytic Leukemia 3 | 262
Endometrial cancer 3 | 311
Epilepsy 3 | 792
Esophageal Neoplasms 3 | 69
Immune system cancer 3 | 140
Leukemia, Lymphocytic, Chronic, B-Cell 3 | 34
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Lymphoma, T-Cell, Cutaneous 3 | 22
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Myocardial Infarction 3 | 151
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Polycystic ovary syndrome 3 | 360
Seizures 3 | 596
Short stature 3 | 531
Small cell carcinoma of lung 3 | 45
Splenomegaly 3 | 190
Stomach Neoplasms 3 | 300
Urinary Bladder Neoplasms 3 | 114
adrenocortical carcinoma 3 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
breast carcinoma 3 | 1,638
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
invasive ductal carcinoma 3 | 2,951
juvenile dermatomyositis 3 | 1,187
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Adenocarcinoma of lung 2 | 142
Anemia 2 | 365
Blepharoptosis 2 | 231
Brain Ischemia 2 | 110
Broad flat nasal bridge 2 | 236
Carcinoma, Transitional Cell 2 | 32
Colonic Neoplasms 2 | 142
Infertility, Male 2 | 46
Kidney disease 2 | 430
Large intestine cancer 2 | 126
Leukemia 2 | 104
Liver cancer 2 | 604
Male infertility 2 | 206
Microcephaly 2 | 166
Microstomia 2 | 78
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Penile hypospadias 2 | 106
Strabismus 2 | 270
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
chronic lymphosyte leukemia 2 | 204
lung adenocarcinoma 2 | 2,716
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
pancreatic carcinoma 2 | 562
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 13 | 12,091
Transcription Factor 4 | 1,400
Enzyme 1 | 4,145
Epigenetic 1 | 242
Kinase 1 | 634

Reactome Pathway

TP53 Regulates Transcription o... 20 | 20
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.70122 462.2 347
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like BNIP3L Tbio Non-IDG -2.20837 153.7 355
p53-regulated apoptosis-inducing protein 1 TP53AIP1 Tbio Non-IDG -1.34343 17.8 97
BH3-interacting domain death agonist BID Tbio Non-IDG -1.85313 58.9 981
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.02081 88.0 559
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
TP53-regulated inhibitor of apoptosis 1 TRIAP1 Tbio Non-IDG -2.40333 252.7 16