Development Level

Tbio 17 | 10,625
Tchem 4 | 1,890

Disease

Cancer 12 | 2,346
ovarian cancer 12 | 8,484
osteosarcoma 11 | 7,933
medulloblastoma, large-cell 10 | 6,234
lung cancer 8 | 4,466
psoriasis 8 | 6,685
Breast cancer 7 | 3,094
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 6 | 5,572
malignant mesothelioma 6 | 3,162
adult high grade glioma 5 | 2,148
group 3 medulloblastoma 5 | 2,254
non primary Sjogren syndrome sicca 5 | 840
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
tuberculosis 5 | 1,557
Amyotrophic Lateral Sclerosis 4 | 431
Lymphoid leukemia 4 | 69
Prostatic Neoplasms 4 | 471
acute quadriplegic myopathy 4 | 1,157
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,950
pilocytic astrocytoma 4 | 3,086
primitive neuroectodermal tumor 4 | 3,031
Adenoid Cystic Carcinoma 3 | 99
Bladder Neoplasm 3 | 109
Carcinoma 3 | 2,147
Chronic Lymphocytic Leukemia 3 | 242
Esophageal Neoplasms 3 | 67
Immune system cancer 3 | 38
Liver carcinoma 3 | 217
Lymphoma, T-Cell, Cutaneous 3 | 21
Mammary Neoplasms 3 | 410
Pancreatic Neoplasm 3 | 79
Small cell carcinoma of lung 3 | 45
Stomach Neoplasms 3 | 282
adrenocortical carcinoma 3 | 1,427
astrocytic glioma 3 | 2,241
astrocytoma 3 | 1,493
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
breast carcinoma 3 | 1,614
esophageal adenocarcinoma 3 | 737
gastric carcinoma 3 | 832
group 4 medulloblastoma 3 | 1,875
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,713
non-small cell lung cancer 3 | 2,798
pancreatic carcinoma 3 | 567
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 2,087
Acute kidney injury 2 | 65
Adenocarcinoma 2 | 115
Brain Ischemia 2 | 87
Carcinoma, Transitional Cell 2 | 31
Colonic Neoplasms 2 | 126
Colorectal Neoplasms 2 | 217
Diabetes Mellitus, Experimental 2 | 106
Ischemia 2 | 27
Kidney cancer 2 | 118
Kidney disease 2 | 396
Lung Neoplasms 2 | 171
Male infertility 2 | 170
Melanoma 2 | 261
Multiple myeloma 2 | 1,327
Myocardial Infarction 2 | 126
Neoplasm Metastasis 2 | 138
Neoplastic Cell Transformation 2 | 81
Neoplastic Syndromes, Hereditary 2 | 48
Neurodegenerative disease 2 | 383
Nijmegen breakage syndrome 2 | 23
Peripheral Neuropathy 2 | 303
Polycystic Ovary Syndrome 2 | 332
Sezary Syndrome 2 | 26
Squamous cell carcinoma 2 | 94
Squamous cell carcinoma of esophagus 2 | 82
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
chronic lymphosyte leukemia 2 | 232
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
fibroadenoma 2 | 557
gastric cancer 2 | 430
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 532
lung carcinoma 2 | 2,844
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
pediatric high grade glioma 2 | 2,712
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
spina bifida 2 | 1,064
Hemangioma 1 | 35
Malignant neoplasm of lung 1 | 16
Neurofibromatosis 1 | 37
Xeroderma pigmentosum 1 | 41

Tissue

Blood and immune system 21 | 17,995
Digestive Tract 21 | 18,473
Female tissues 21 | 18,647
Liver and Pancreas 21 | 18,136
Male tissues 21 | 17,969
Nervous System 21 | 18,561
Respiratory system 21 | 17,484
Urinary Tract 21 | 18,444
Cardiovascular System 20 | 17,958
Endocrine System 20 | 18,512
Skin and soft tissues 20 | 18,115

Target Family

Non-IDG 14 | 11,971
Transcription Factor 4 | 1,400
Enzyme 1 | 4,146
Epigenetic 1 | 242
Kinase 1 | 634

Reactome Pathway

TP53 Regulates Transcription o... 21 | 21
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phorbol-12-myristate-13-acetate-induced protein 1 PMAIP1 Tbio Non-IDG -2.66052 440.9 327
TP53-regulated inhibitor of apoptosis 1 TRIAP1 Tbio Non-IDG -2.36887 245.1 9
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.80161 68.4 178
Bcl-2-binding component 3 BBC3 Tbio Non-IDG 79.2 511
Apoptosis-inducing factor 2 AIFM2 Tbio Non-IDG -1.17873 16.2 195
Bcl-2-binding component 3 BBC3 Tbio Non-IDG -2.09170 79.2 511
BH3-interacting domain death agonist BID Tbio Non-IDG -1.78154 53.0 854
p53-regulated apoptosis-inducing protein 1 TP53AIP1 Tbio Non-IDG -1.31676 16.6 89
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.67490 51004.8 5255
Tumor protein p73 TP73 Tbio Transcription Factor -1.91475 80.6 642