Development Level

Tbio 7 | 11,651
Tchem 3 | 1,388
Tdark 1 | 6,593

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal lung morphology 1 | 26
abnormal urinary bladder morph... 1 | 11
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
enlarged heart 1 | 210
short tibia 1 | 97

Disease

Cancer 9 | 2,499
Carcinoma 8 | 11,493
lung cancer 7 | 4,740
osteosarcoma 7 | 7,950
ovarian cancer 6 | 8,520
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
ependymoma 5 | 4,679
glioblastoma 5 | 5,792
acute myeloid leukemia 4 | 783
juvenile dermatomyositis 4 | 1,187
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
psoriasis 4 | 6,694
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Adenocarcinoma 3 | 122
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Breast cancer 3 | 3,578
Colorectal Neoplasms 3 | 243
Liver disease 3 | 237
Lung Neoplasms 3 | 232
Pancreatic Neoplasm 3 | 85
Pancreatic Neoplasms 3 | 85
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Squamous cell carcinoma 3 | 129
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Adenocarcinoma of lung (disorder) 2 | 60
Alopecia 2 | 115
Amyotrophic lateral sclerosis 2 | 451
Anemia 2 | 365
Autosomal recessive predisposition 2 | 1,442
Barrett's esophagus 2 | 182
Bladder Neoplasm 2 | 112
Carcinoma, Squamous Cell 2 | 110
Carcinoma, Transitional Cell 2 | 32
Carcinoma, squamous cell of head and neck 2 | 31
Cell Transformation, Neoplastic 2 | 97
Chronic Lymphocytic Leukemia 2 | 262
Colonic Neoplasms 2 | 142
Esophageal Neoplasms 2 | 69
Hypersensitivity reaction type II disease 2 | 253
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Liver Neoplasms, Experimental 2 | 59
Lymphoid leukemia 2 | 160
Melanoma 2 | 711
Nausea 2 | 20
Neoplasm Metastasis 2 | 168
Neoplastic Cell Transformation 2 | 89
Skin cancer 2 | 469
Small cell carcinoma of lung 2 | 45
Squamous cell carcinoma of the head and neck 2 | 29
Stomach Neoplasms 2 | 300
Thrombocytopenia 2 | 197
Urinary Bladder Neoplasms 2 | 114
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
gastric carcinoma 2 | 807
lung carcinoma 2 | 2,843
lung small cell carcinoma 2 | 4
pituitary cancer 2 | 1,972
Aplastic/hypoplastic phalanges 1 | 3
Central Diabetes Insipidus 1 | 5
Cleft lip and alveolus 1 | 4
Dacryocystitis 1 | 11
Drug Hypersensitivity 1 | 34
Dystrophic fingernails 1 | 18
Generalized hyperpigmentation 1 | 22
Generalized hypopigmentation 1 | 12
Isolated somatotropin deficiency 1 | 30
Missing more than six teeth 1 | 22
Nonsyndromic congenital nail disorder 1 1 | 3
Peg-shaped teeth 1 | 8
Peripheral Nervous System Diseases 1 | 52
Pointed teeth 1 | 8
Renal hypoplasia/aplasia 1 | 7
Slow-growing hair 1 | 19
Submucous cleft of hard palate 1 | 11
Submucous clefting 1 | 9
Triphalangeal thumb 1 | 9
Xerostomia 1 | 42

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 8 | 12,091
Transcription Factor 3 | 1,400

Reactome Pathway

TP53 Regulates Transcription o... 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Insulin-like growth factor-binding protein 3 IGFBP3 Tchem Non-IDG -3.35760 2176.5 510
Cellular tumor antigen p53 TP53 Tchem Transcription Factor -4.74112 54026.3 6298
Tumor protein 63 TP63 Tbio Transcription Factor -3.07398 1154.1 448
Tumor necrosis factor receptor superfamily member 10B TNFRSF10B Tbio Non-IDG -3.15963 1514.8 849
Tumor necrosis factor receptor superfamily member 10C TNFRSF10C Tbio Non-IDG -2.62662 407.7 467
Tumor necrosis factor receptor superfamily member 10A TNFRSF10A Tchem Non-IDG -3.41373 2664.2 812
Tumor protein p73 TP73 Tbio Transcription Factor -1.92832 82.6 708
Insulin-like growth factor-binding protein 3 receptor TMEM219 Tdark Non-IDG -0.29618 1.24 8
Apoptosis-stimulating of p53 protein 2 TP53BP2 Tbio Non-IDG -1.85307 72.5 189
Tumor necrosis factor receptor superfamily member 10D TNFRSF10D Tbio Non-IDG -1.56860 41.3 505