Development Level

Tbio 6 | 11,445
Tclin 5 | 613

IMPC Phenotype

decreased leukocyte cell numbe... 1 | 73
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 10 | 8,520
Breast cancer 9 | 3,578
lung cancer 9 | 4,740
psoriasis 9 | 6,694
Cancer 8 | 2,499
osteosarcoma 8 | 7,950
Carcinoma 7 | 11,493
atypical teratoid / rhabdoid tumor 7 | 5,112
Kidney cancer 6 | 2,613
interstitial cystitis 6 | 2,312
Breast Neoplasms 5 | 445
Disease Progression 5 | 136
Mammary Neoplasms 5 | 425
Neoplasm Recurrence, Local 5 | 37
Prostatic Neoplasms 5 | 495
Stomach Neoplasms 5 | 300
cutaneous lupus erythematosus 5 | 1,057
ductal carcinoma in situ 5 | 1,745
glioblastoma 5 | 5,792
non-small cell lung cancer 5 | 2,890
ulcerative colitis 5 | 1,819
Adenocarcinoma 4 | 122
Adenoma 4 | 167
Carcinoma, Non-Small-Cell Lung 4 | 107
Exanthem 4 | 37
Heart disease 4 | 306
Mammary Neoplasms, Animal 4 | 136
Mammary Neoplasms, Experimental 4 | 154
Neoplasm Metastasis 4 | 168
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
non-small cell lung carcinoma 4 | 317
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Animal Mammary Neoplasms 3 | 136
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Carcinoma, Hepatocellular 3 | 228
Colonic Neoplasms 3 | 142
Craniofacial Abnormalities 3 | 151
Diarrhea 3 | 253
Endometriosis 3 | 540
Head and Neck Neoplasms 3 | 26
Liver carcinoma 3 | 240
Lung Neoplasms 3 | 232
Mucositis 3 | 29
Obesity 3 | 678
Papilloma 3 | 44
Schizophrenia 3 | 1,160
Uterine Cervical Neoplasm 3 | 25
Uterine Cervical Neoplasms 3 | 26
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
astrocytic glioma 3 | 2,597
colon cancer 3 | 1,478
lung carcinoma 3 | 2,843
medulloblastoma, large-cell 3 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Acquired metabolic disease 2 | 336
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer Disease 2 | 83
Anemia 2 | 365
Atherosclerosis 2 | 291
Bladder Neoplasm 2 | 112
Blepharoptosis 2 | 231
Cardiovascular system disease 2 | 246
Coronary artery disease 2 | 268
Disease Models, Animal 2 | 155
Endometrial Neoplasms 2 | 55
Inflammation 2 | 120
Kidney disease 2 | 430
Liver neoplasms 2 | 130
Lung disease 2 | 142
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Mesothelioma 2 | 38
Mesothelioma, Malignant 2 | 105
Mood Disorders 2 | 184
Myopia 2 | 176
Neoplasm Invasiveness 2 | 161
Neuroblastoma 2 | 80
Neuropathy 2 | 261
Neutropenia 2 | 72
Skin cancer 2 | 469
Urinary Bladder Neoplasms 2 | 114
glioblastoma multiforme 2 | 142
gliosarcoma 2 | 18
substance-related disorder 2 | 162

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Liver and Pancreas 10 | 16,750

Target Family

Transcription Factor 4 | 1,400
Kinase 3 | 634
Non-IDG 3 | 12,091
Nuclear Receptor 1 | 48

Reactome Pathway

TFAP2 (AP-2) family regulates ... 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycoprotein hormones alpha chain CGA Tbio Non-IDG -2.62079 405.6 915
Mast/stem cell growth factor receptor Kit KIT Tclin Kinase -3.80501 6371.9 4098
Transcription factor AP-2 gamma TFAP2C Tbio Transcription Factor -1.88406 72.7 269
Protransforming growth factor alpha TGFA Tbio Non-IDG -2.15761 135.3 697
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859
Transcription factor AP-2-alpha TFAP2A Tbio Transcription Factor -2.48414 289.3 396
Vascular endothelial growth factor A VEGFA Tclin Non-IDG -4.27197 19076.6 1809