Development Level

Tchem 6 | 1,388
Tbio 5 | 11,651
Tclin 2 | 612
Tdark 1 | 6,593

IMPC Phenotype

abnormal heart morphology 1 | 162
enlarged heart 1 | 210
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63

Disease

lung cancer 8 | 4,740
non-small cell lung cancer 8 | 2,890
ovarian cancer 8 | 8,520
Cancer 7 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
psoriasis 7 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
ulcerative colitis 6 | 1,819
Astrocytoma, Pilocytic 5 | 3,081
Carcinoma 5 | 11,493
cystic fibrosis 5 | 1,696
glioblastoma 5 | 5,792
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
medulloblastoma, large-cell 5 | 6,241
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
Arthritis 4 | 290
Asthma 4 | 385
Atopic dermatitis 4 | 952
Hypertension 4 | 396
Patent ductus arteriosus 4 | 90
Prostatic Neoplasms 4 | 495
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
ependymoma 4 | 4,679
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Bipolar Disorder 3 | 666
Cerebrovascular disease 3 | 238
Fever 3 | 138
Kidney Failure, Chronic 3 | 46
Liver Cirrhosis, Experimental 3 | 769
Osteoarthritis 3 | 184
Rheumatoid arthritis 3 | 1,191
Thyroid Neoplasm 3 | 37
Thyroid Neoplasms 3 | 34
atypical teratoid / rhabdoid tumor 3 | 5,112
head and neck cancer 3 | 271
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
Abnormal cortical bone morphology 2 | 22
Actinic keratosis 2 | 21
Adenoma 2 | 167
Allergic conjunctivitis 2 | 22
Ankylosing spondylitis 2 | 140
Asthma, Occupational 2 | 10
Breast Neoplasms 2 | 445
Bursitis 2 | 10
Carcinoma, Hepatocellular 2 | 228
Cardiomyopathies 2 | 110
Chemical and Drug Induced Liver Injury 2 | 195
Colonic Neoplasms 2 | 142
Common cold 2 | 69
Coronary artery disease 2 | 268
Diarrhea 2 | 253
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Endometritis 2 | 21
Esophageal Neoplasms 2 | 69
Eye disease 2 | 62
Gaucher disease type 3 2 | 67
Gout 2 | 104
Heart failure 2 | 162
Hydronephrosis 2 | 89
Hyperalgesia 2 | 83
Inflammation 2 | 120
Juvenile rheumatoid arthritis 2 | 111
Kidney Neoplasms 2 | 37
Kidney disease 2 | 430
Liver carcinoma 2 | 240
Liver disease 2 | 237
Mammary Neoplasms 2 | 425
Menorrhagia 2 | 25
Mood Disorders 2 | 184
Myocardial Infarction 2 | 151
Pain 2 | 103
Pain agnosia 2 | 104
Post-Op Ocular Inflammation 2 | 9
Reperfusion Injury 2 | 86
Synovitis 2 | 78
Tendinitis 2 | 14
Tenosynovitis 2 | 14
Toxic encephalopathy 2 | 141
Urticaria 2 | 67
adrenocortical adenoma 2 | 131
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
medulloblastoma 2 | 720
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
pulmonary tuberculosis 2 | 9

Tissue

Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Nervous System 13 | 16,725
Respiratory system 13 | 16,393

Target Family

Enzyme 14 | 4,145

Reactome Pathway

Synthesis of Prostaglandins (P... 14 | 14
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.23035 1641.3 479
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.06834 12504.5 731
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.16512 1395.9 264
Prostaglandin E synthase 3 PTGES3 Tbio Enzyme -1.86748 64.9 464
Prostacyclin synthase PTGIS Tbio Enzyme -2.55019 341.8 152
15-hydroxyprostaglandin dehydrogenase [NAD(+)] HPGD Tchem Enzyme -2.26841 191.0 354
Prostaglandin-H2 D-isomerase PTGDS Tbio Enzyme -2.58623 410.9 229
Prostaglandin E synthase PTGES Tchem Enzyme -3.05403 1164.2 151
Carbonyl reductase [NADPH] 1 CBR1 Tchem Enzyme -2.00623 106.8 274
Prostaglandin E synthase 2 PTGES2 Tchem Enzyme -1.65834 34.9 176