Development Level

Tchem 8 | 1,890
Tbio 4 | 10,625
Tclin 2 | 602
Tdark 1 | 7,003

IMPC Term

increased mean corpuscular hem... 1 | 93

Disease

lung cancer 9 | 4,466
non-small cell lung cancer 9 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
ovarian cancer 8 | 8,484
Cancer 7 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
invasive ductal carcinoma 7 | 2,950
lung carcinoma 7 | 2,844
pancreatic cancer 7 | 2,300
psoriasis 7 | 6,685
glioblastoma 6 | 5,572
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
lung adenocarcinoma 6 | 2,713
malignant mesothelioma 6 | 3,162
medulloblastoma, large-cell 6 | 6,234
oligodendroglioma 6 | 2,849
osteosarcoma 6 | 7,933
ulcerative colitis 6 | 2,087
Atopic dermatitis 5 | 944
Patent ductus arteriosus 5 | 23
Prostatic Neoplasms 5 | 471
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,665
pilocytic astrocytoma 5 | 3,086
subependymal giant cell astrocytoma 5 | 2,287
Asthma 4 | 349
Hypertension 4 | 287
Osteoarthritis 4 | 96
Rheumatoid Arthritis 4 | 1,160
adrenocortical carcinoma 4 | 1,427
head and neck cancer 4 | 270
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pediatric high grade glioma 4 | 2,712
tuberculosis 4 | 1,557
Ankylosing spondylitis 3 | 138
Arthritis 3 | 248
Bursitis 3 | 10
Bursitis of shoulder 3 | 4
Cerebrovascular disease 3 | 231
Dysmenorrhea 3 | 19
Fever 3 | 34
Gout 3 | 93
Headache disorder 3 | 20
Joint pain 3 | 8
Juvenile rheumatoid arthritis 3 | 104
Menorrhagia 3 | 8
Migraine 3 | 79
Muscle pain 3 | 3
Nasal discharge 3 | 26
Pain 3 | 70
Peripheral Neuropathy 3 | 303
Shoulder Tendonitis 3 | 4
Sinus headache 3 | 17
Synovitis 3 | 38
Tendinitis 3 | 13
Tenosynovitis 3 | 15
Thyroid Neoplasm 3 | 33
Toothache 3 | 6
aldosterone-producing adenoma 3 | 664
astrocytoma 3 | 1,493
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 2,254
group 4 medulloblastoma 3 | 1,875
medulloblastoma 3 | 1,524
posterior fossa group B ependymoma 3 | 1,530
primitive neuroectodermal tumor 3 | 3,031
Adenoma 2 | 165
Amyotrophic Lateral Sclerosis 2 | 431
Cardiomyopathies 2 | 90
Colonic Neoplasms 2 | 126
Common cold 2 | 63
Coronary artery disease 2 | 240
Diarrhea 2 | 155
Drug allergy 2 | 36
Drug-Induced Liver Injury 2 | 118
Endometriosis 2 | 535
Esophageal Neoplasms 2 | 67
Gaucher disease type 3 2 | 76
Heart failure 2 | 80
Hydronephrosis 2 | 19
Hyperalgesia 2 | 71
Inflammation 2 | 109
Kidney disease 2 | 396
Liver carcinoma 2 | 217
Liver disease 2 | 219
Lung Neoplasms 2 | 171
Mammary Neoplasms 2 | 410
Pain agnosia 2 | 99
Reperfusion Injury 2 | 84
Stomach Neoplasms 2 | 282
Toxic encephalopathy 2 | 131
adrenocortical adenoma 2 | 134
adult high grade glioma 2 | 2,148
head and neck cancer and chronic obstructive pulmonary disease 2 | 237
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
pituitary cancer 2 | 1,972

Tissue

Blood and immune system 15 | 17,995
Cardiovascular System 15 | 17,958
Digestive Tract 15 | 18,473
Endocrine System 15 | 18,512
Female tissues 15 | 18,647
Liver and Pancreas 15 | 18,136
Male tissues 15 | 17,969
Nervous System 15 | 18,561
Respiratory system 15 | 17,484
Skin and soft tissues 15 | 18,115
Urinary Tract 15 | 18,444

Target Family

Enzyme 15 | 4,146

Reactome Pathway

Synthesis of Prostaglandins (P... 15 | 15
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin G/H synthase 1 PTGS1 Tclin Enzyme -3.20847 1594.9 391
Prostaglandin G/H synthase 2 PTGS2 Tclin Enzyme -4.03668 12041.6 648
Thromboxane-A synthase TBXAS1 Tchem Enzyme -3.06668 1228.9 241
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase CYP8B1 Tbio Enzyme -1.59796 38.3 100
Prostaglandin-H2 D-isomerase PTGDS Tchem Enzyme -2.54805 391.3 214
15-hydroxyprostaglandin dehydrogenase [NAD(+)] HPGD Tchem Enzyme -2.21465 176.6 308
Prostamide/prostaglandin F synthase FAM213B Tdark Enzyme -0.09691 0.67 56
Prostaglandin E synthase 2 PTGES2 Tchem Enzyme -1.62138 33.3 154
Prostaglandin E synthase PTGES Tchem Enzyme -3.01027 1099.8 145
Prostaglandin E synthase 3 PTGES3 Tbio Enzyme -1.89774 59.3 384