Development Level

Tbio 4 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal embryo size 1 | 220
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased mean corpuscular hem... 1 | 50
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased red blood cell distr... 1 | 34
thrombocytopenia 1 | 56

Disease

osteosarcoma 5 | 7,950
Carcinoma 3 | 11,493
ependymoma 3 | 4,679
oligodendroglioma 3 | 2,850
ovarian cancer 3 | 8,520
Cardiomegaly 2 | 116
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
non primary Sjogren syndrome sicca 2 | 891
pancreatic cancer 2 | 2,398
ALZHEIMER DISEASE 19 1 | 1
Acute hemorrhagic conjunctivitis 1 | 4
Alzheimer's disease 1 | 658
Arthritis, Rheumatoid 1 | 174
Astrocytoma, Pilocytic 1 | 3,081
Barth syndrome 1 | 23
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Centronuclear myopathy 1 | 27
Conjunctivitis 1 | 53
Heavy chain disease 1 | 6
Hypervitaminosis A 1 | 13
Inclusion conjunctivitis 1 | 8
Infarction, Middle Cerebral Artery 1 | 33
Keratoconjunctivitis 1 | 14
Kidney cancer 1 | 2,613
Liver Cirrhosis, Experimental 1 | 769
Oculocerebrorenal syndrome 1 | 29
Orthomyxoviridae Infections 1 | 1
Rheumatoid arthritis 1 | 1,191
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
lung cancer 1 | 4,740
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung cancer 1 | 2,890
pancreatic carcinoma 1 | 562
pituitary cancer 1 | 1,972
progressive supranuclear palsy 1 | 676
psoriasis 1 | 6,694
pterygium 1 | 76
spina bifida 1 | 1,074
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Digestive Tract 7 | 17,369
Endocrine System 7 | 18,159
Female tissues 7 | 17,400
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Nervous System 7 | 16,725
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Enzyme 7 | 4,145

Reactome Pathway

Synthesis of PG 7 | 7
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 PTPMT1 Tbio Enzyme -1.36243 23.0 109
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial PGS1 Tdark Enzyme -0.35218 2.20 123
Phospholipase D3 PLD3 Tbio Enzyme -1.77419 62.1 99
Phospholipase D4 PLD4 Tbio Enzyme -0.92277 9.56 136
Phospholipase D2 PLD2 Tchem Enzyme -2.47197 312.2 172
Phospholipase D1 PLD1 Tchem Enzyme -1.51188 30.9 203
Mitochondrial cardiolipin hydrolase PLD6 Tbio Enzyme -1.90990 78.3 63