Development Level

Tbio 12 | 11,651
Tchem 4 | 1,388
Tclin 2 | 612
Tdark 2 | 6,593

IMPC Phenotype

abnormal bone structure 1 | 187
abnormal clavicle morphology 1 | 6
abnormal joint morphology 1 | 23
abnormal optic disc morphology 1 | 10
abnormal seminal vesicle morph... 1 | 114
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased lymphocyte cell numb... 1 | 83
decreased mean platelet volume 1 | 25
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
small superior vagus ganglion 1 | 74

Disease

Carcinoma 14 | 11,493
osteosarcoma 13 | 7,950
psoriasis 10 | 6,694
interstitial cystitis 8 | 2,312
lung cancer 8 | 4,740
non-small cell lung cancer 7 | 2,890
ovarian cancer 7 | 8,520
Asthma 5 | 385
Atherosclerosis 5 | 291
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
Hypertension 4 | 396
adrenocortical carcinoma 4 | 1,428
invasive ductal carcinoma 4 | 2,951
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Rheumatoid arthritis 3 | 1,191
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Endometriosis 2 | 540
Liver diseases 2 | 87
Melanoma 2 | 711
Peritonitis 2 | 43
Rhinitis 2 | 55
Urticaria 2 | 67
active Crohn's disease 2 | 922
astrocytoma 2 | 1,146
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
group 3 medulloblastoma 2 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
periodontitis 2 | 293
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
primitive neuroectodermal tumor 2 | 3,035
urothelial carcinoma 2 | 318
Actinic keratosis 1 | 21
Alcohol dependence 1 | 107
Alcoholism 1 | 45
Animal Mammary Neoplasms 1 | 136
Autosomal recessive congenital ichthyosis 1 | 11
Bilirubin metabolic disorder 1 | 41
COPD 1 | 118
Cataract 4 multiple types 1 | 14
Cholangitis 1 | 32
Choledocholithiasis 1 | 11
Chromosome 17q12 deletion syndrome 1 | 16
Chronic heart failure 1 | 46
Colonic Polyps 1 | 3
Common cold 1 | 69
Common variable immunodeficiency 1 | 101
Drug Eruptions 1 | 18
Drug allergy 1 | 36
Ectropion 1 | 38
Endometritis 1 | 21
Esophageal Neoplasms 1 | 69
Fatty liver disease 1 | 103
Hepatitis C 1 | 94
Hypertension, Pulmonary 1 | 37
Hypertensive disorder 1 | 57
Infarction, Middle Cerebral Artery 1 | 33
Infection of bone 1 | 19
Juvenile rheumatoid arthritis 1 | 111
Liver disease 1 | 237
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Meningitis 1 | 67
Menorrhagia 1 | 25
Myocardial Infarction 1 | 151
Neoplasm Metastasis 1 | 168
Pain 1 | 103
Pancreatitis 1 | 123
Pulmonary hypertension 1 | 86
Pyelonephritis 1 | 13
Scrub typhus 1 | 7
Skin disease 1 | 66
Spondylosis 1 | 16
Substance abuse 1 | 59
chronic kidney disease 1 | 90
inflammatory breast cancer 1 | 286
sarcoidosis 1 | 370
uncontrolled asthma 1 | 56

Tissue

Digestive Tract 20 | 17,369
Female tissues 20 | 17,400
Male tissues 20 | 17,142
Endocrine System 19 | 18,159
Liver and Pancreas 19 | 16,750
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Blood and immune system 17 | 16,909
Cardiovascular System 15 | 15,192

Target Family

Enzyme 14 | 4,145
Non-IDG 5 | 12,091
Kinase 1 | 634

Reactome Pathway

Synthesis of Leukotrienes (LT)... 20 | 20
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 4A22 CYP4A22 Tbio Non-IDG -0.92876 6.79 75
MAP kinase-activated protein kinase 2 MAPKAPK2 Tchem Kinase -2.16502 140.7 702
Dipeptidase 1 DPEP1 Tclin Enzyme -2.47338 295.7 145
Cytochrome P450 4B1 CYP4B1 Tbio Non-IDG -1.80695 66.9 104
Glutathione hydrolase 5 proenzyme GGT5 Tbio Enzyme -1.89298 76.6 76
Dipeptidase 3 DPEP3 Tbio Enzyme -0.73860 5.04 89
Dipeptidase 2 DPEP2 Tdark Enzyme -0.89574 6.83 34
Arachidonate 5-lipoxygenase-activating protein ALOX5AP Tchem Enzyme -2.68134 446.8 174
Arachidonate 5-lipoxygenase ALOX5 Tclin Enzyme -3.12710 1408.9 492
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -2.03967 107.1 42