Development Level

Tbio 11 | 10,625
Tchem 5 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

IMPC Phenotype

abnormal bone structure 1 | 131
abnormal joint morphology 1 | 14
abnormal optic disc morphology 1 | 10
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral content 1 | 157
decreased cervical vertebrae n... 1 | 12
decreased circulating iron lev... 1 | 25
decreased circulating triglyce... 1 | 83
decreased mean platelet volume 1 | 12
hyperactivity 1 | 108
increased circulating glucose ... 1 | 16
increased circulating iron lev... 1 | 25
short tibia 1 | 82

Disease

osteosarcoma 14 | 7,933
psoriasis 11 | 6,685
interstitial cystitis 8 | 2,299
lung cancer 8 | 4,473
non-small cell lung cancer 8 | 2,798
ovarian cancer 8 | 8,491
lung carcinoma 6 | 2,844
Asthma 5 | 349
Atherosclerosis 5 | 275
lung adenocarcinoma 5 | 2,714
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
ulcerative colitis 5 | 2,087
Cancer 4 | 2,346
Hypertension 4 | 293
adrenocortical carcinoma 4 | 1,427
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
invasive ductal carcinoma 4 | 2,950
malignant mesothelioma 4 | 3,163
medulloblastoma, large-cell 4 | 6,234
pancreatic cancer 4 | 2,300
pilocytic astrocytoma 4 | 3,086
Rheumatoid Arthritis 3 | 1,170
active Crohn's disease 3 | 918
glioblastoma 3 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
posterior fossa group A ependymoma 3 | 1,511
primary pancreatic ductal adenocarcinoma 3 | 1,271
Breast cancer 2 | 3,098
Cerebrovascular disease 2 | 231
Coronary artery disease 2 | 240
Endometriosis 2 | 535
Hypertensive disease 2 | 193
Liver diseases 2 | 66
Urticaria 2 | 53
astrocytoma 2 | 1,493
atypical teratoid / rhabdoid tumor 2 | 4,369
cutaneous lupus erythematosus 2 | 1,056
cystic fibrosis 2 | 1,670
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,663
medulloblastoma 2 | 1,524
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pediatric high grade glioma 2 | 2,712
periodontitis 2 | 269
pituitary cancer 2 | 1,972
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
primitive neuroectodermal tumor 2 | 3,031
tuberculosis 2 | 1,563
urothelial carcinoma 2 | 318
ATHEROSCLEROSIS, SUSCEPTIBILITY TO 1 | 3
Actinic keratosis 1 | 22
Adverse reaction to drug 1 | 54
Alcohol dependence 1 | 107
Alcoholic Intoxication, Chronic 1 | 41
Animal Mammary Neoplasms 1 | 135
Asthma management 1 | 20
Bilirubin metabolic disorder 1 | 39
COPD 1 | 116
Cholangitis 1 | 20
Choledocholithiasis 1 | 13
Chromosome 17q12 deletion syndrome 1 | 16
Chronic heart failure 1 | 46
Colonic Polyps 1 | 3
Colorectal Neoplasms 1 | 217
Common variable immunodeficiency 1 | 98
Drug Eruptions 1 | 18
Endometritis 1 | 21
Esophageal Neoplasms 1 | 67
Fatty liver disease 1 | 86
Heart Diseases 1 | 42
Hepatitis C 1 | 90
Hypertensive disorder 1 | 58
Infarction, Middle Cerebral Artery 1 | 25
Ischemic stroke 1 | 12
Juvenile rheumatoid arthritis 1 | 105
Liver disease 1 | 219
Mammary Neoplasms 1 | 410
Mammary Neoplasms, Experimental 1 | 149
Melanoma 1 | 261
Meningitis 1 | 46
Menorrhagia 1 | 8
Myocardial Infarction 1 | 126
Neoplasm Invasiveness 1 | 127
Neoplasm Metastasis 1 | 138
Osteoarthritis 1 | 96
Pain 1 | 70
Pancreatitis 1 | 97
Pseudoxanthoma elasticum 1 | 19
Pulmonary hypertension 1 | 52
Pyelonephritis 1 | 12
Rhinitis 1 | 46
Scrub typhus 1 | 7
Squamous cell carcinoma of the head and neck 1 | 24
Substance abuse 1 | 55
chronic kidney disease 1 | 90
sarcoidosis 1 | 368
uncontrolled asthma 1 | 67

Tissue

Blood and immune system 21 | 17,994
Cardiovascular System 21 | 17,957
Digestive Tract 21 | 18,472
Endocrine System 21 | 18,511
Female tissues 21 | 18,646
Liver and Pancreas 21 | 18,135
Male tissues 21 | 17,968
Nervous System 21 | 18,560
Skin and soft tissues 21 | 18,114
Urinary Tract 21 | 18,443
Respiratory system 20 | 17,483

Target Family

Enzyme 14 | 4,146
Non-IDG 5 | 11,969
Kinase 1 | 634
Transporter 1 | 473

Reactome Pathway

Synthesis of Leukotrienes (LT)... 21 | 21
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome P450 4A22 CYP4A22 Tbio Non-IDG -0.91578 6.79 68
Dipeptidase 3 DPEP3 Tdark Enzyme -0.73860 4.89 74
Dipeptidase 2 DPEP2 Tdark Enzyme -0.86722 6.28 32
Docosahexaenoic acid omega-hydroxylase CYP4F3 CYP4F3 Tbio Enzyme -1.69323 47.4 107
Cytochrome P450 4F22 CYP4F22 Tbio Non-IDG -2.01637 100.6 25
Arachidonate 5-lipoxygenase ALOX5 Tclin Enzyme -3.10636 1353.0 439
Multidrug resistance-associated protein 1 ABCC1 Tchem Transporter -2.77845 626.0 274
Leukotriene A-4 hydrolase LTA4H Tchem Enzyme -2.07129 115.0 264
Arachidonate 5-lipoxygenase-activating protein ALOX5AP Tchem Enzyme -2.65178 446.8 164
Cytochrome P450 4F8 CYP4F8 Tdark Non-IDG 0.00000 28