Development Level

Tbio 15 | 10,625
Tchem 4 | 1,890
Tclin 4 | 602
Tdark 1 | 7,003

IMPC Term

decreased CD8-positive, naive ... 1 | 5
embryonic lethality prior to o... 1 | 148
increased bone mineral content 1 | 92
increased memory CD4-positive,... 1 | 3
preweaning lethality, complete... 1 | 633

Disease

lung cancer 13 | 4,466
medulloblastoma, large-cell 12 | 6,234
ovarian cancer 12 | 8,484
Breast cancer 9 | 3,094
glioblastoma 9 | 5,572
osteosarcoma 9 | 7,933
Cancer 8 | 2,346
oligodendroglioma 8 | 2,849
atypical teratoid / rhabdoid tumor 7 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
malignant mesothelioma 7 | 3,162
non-small cell lung cancer 7 | 2,798
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
psoriasis 7 | 6,685
tuberculosis 7 | 1,557
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
invasive ductal carcinoma 6 | 2,950
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
ependymoma 5 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,713
subependymal giant cell astrocytoma 5 | 2,287
Multiple myeloma 4 | 1,327
Pick disease 4 | 1,893
Reticular dysgenesis 4 | 7
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
nasopharyngeal carcinoma 4 | 1,056
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
ulcerative colitis 4 | 2,087
Amyotrophic Lateral Sclerosis 3 | 431
Colorectal Neoplasms 3 | 217
Contact Dermatitis 3 | 80
Endometriosis 3 | 535
Liver carcinoma 3 | 217
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
Acute lymphoid leukemia 2 | 25
Adenocarcinoma of pancreas 2 | 12
Atopic dermatitis 2 | 944
Atrial Fibrillation 2 | 110
Barrett's esophagus 2 | 183
Chronic myeloid leukemia 2 | 11
Degenerative polyarthritis 2 | 93
Epilepsy 2 | 346
Hb SS disease 2 | 2
Hemoglobin SS disease with crisis 2 | 2
IGA Glomerulonephritis 2 | 454
Malignant melanoma 2 | 2
Malignant tumor of head and/or neck 2 | 15
Malignant tumor of ovary 2 | 25
Metastatic Breast Carcinoma 2 | 21
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 127
Neurodegenerative disease 2 | 383
Polycystic Ovary Syndrome 2 | 332
Schistosomiasis 2 | 38
Vascular disease 2 | 281
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 933
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
lung carcinoma 2 | 2,844
non-small cell lung carcinoma 2 | 413
posterior fossa group A ependymoma 2 | 1,511
relapsing-remitting multiple sclerosis 2 | 18
Adenoma 1 | 165
Amphetamine-Related Disorders 1 | 74
Anemia 1 | 252
Anoxia 1 | 33
Chronic Lymphocytic Leukemia 1 | 242
Chronic progressive external ophthalmoplegia 1 | 18
Congenital myasthenic syndrome 1 | 28
De Vaal's syndrome 1 | 1
Deafness 1 | 18
Disease Progression 1 | 125
Gaucher disease type 1 1 | 171
Kidney Diseases 1 | 86
Mesothelioma 1 | 40
Multiple Sclerosis 1 | 498
Neuroblastoma 1 | 78
Neuropathy 1 | 210
Pellagra 1 | 25
Peripheral Neuropathy 1 | 303
Severe Combined Immunodeficiency 1 | 46
Toxic encephalopathy 1 | 131
Venous Thromboembolism 1 | 34
cystic fibrosis and chronic rhinosinusitis 1 | 213
gliosarcoma 1 | 19

Tissue

Blood and immune system 24 | 17,995
Cardiovascular System 24 | 17,958
Digestive Tract 24 | 18,473
Endocrine System 24 | 18,512
Female tissues 24 | 18,647
Liver and Pancreas 24 | 18,136
Male tissues 24 | 17,969
Nervous System 24 | 18,561
Respiratory system 24 | 17,484
Skin and soft tissues 24 | 18,115
Urinary Tract 24 | 18,444

Target Family

Kinase 12 | 634
Enzyme 9 | 4,146
Non-IDG 3 | 11,971

Reactome Pathway

Synthesis and interconversion ... 24 | 24
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.97339 830.6 224
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.87012 86.4 226
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.87702 843.2 611
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.78756 72.1 178
Nucleoside diphosphate-linked moiety X motif 13 NUDT13 Tdark Non-IDG -0.09691 1.06 29
Adenylate kinase 9 AK9 Tbio Kinase -0.87467 9.15 83
Adenylate kinase 4, mitochondrial AK4 Tchem Kinase -1.81385 64.9 250
Adenylate kinase isoenzyme 6 AK6 Tbio Kinase -2.37301 215.0 83
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -1.96028 90.6 267
CTP synthase 1 CTPS1 Tbio Enzyme -2.21611 173.3 86