Development Level

Tbio 15 | 10,625
Tchem 4 | 1,890
Tclin 4 | 602
Tdark 1 | 7,003

IMPC Phenotype

decreased CD8-positive, naive ... 1 | 5
embryonic lethality prior to o... 1 | 148
increased bone mineral content 1 | 92
increased memory CD4-positive,... 1 | 3
preweaning lethality, complete... 1 | 633

Disease

lung cancer 13 | 4,473
medulloblastoma, large-cell 12 | 6,234
ovarian cancer 12 | 8,491
Breast cancer 9 | 3,098
glioblastoma 9 | 5,572
osteosarcoma 9 | 7,933
Cancer 8 | 2,346
oligodendroglioma 8 | 2,849
atypical teratoid / rhabdoid tumor 7 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
malignant mesothelioma 7 | 3,163
non-small cell lung cancer 7 | 2,798
pediatric high grade glioma 7 | 2,712
primitive neuroectodermal tumor 7 | 3,031
psoriasis 7 | 6,685
tuberculosis 7 | 1,563
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
invasive ductal carcinoma 6 | 2,950
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
ependymoma 5 | 2,514
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,714
subependymal giant cell astrocytoma 5 | 2,287
Multiple myeloma 4 | 1,327
Pick disease 4 | 1,893
Reticular dysgenesis 4 | 7
adrenocortical carcinoma 4 | 1,427
astrocytic glioma 4 | 2,241
group 3 medulloblastoma 4 | 2,254
medulloblastoma 4 | 1,524
nasopharyngeal carcinoma 4 | 1,056
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
pilocytic astrocytoma 4 | 3,086
posterior fossa group B ependymoma 4 | 1,530
primary pancreatic ductal adenocarcinoma 4 | 1,271
ulcerative colitis 4 | 2,087
Amyotrophic Lateral Sclerosis 3 | 432
Colorectal Neoplasms 3 | 217
Contact Dermatitis 3 | 80
Endometriosis 3 | 535
Liver carcinoma 3 | 217
atypical teratoid/rhabdoid tumor 3 | 1,095
breast carcinoma 3 | 1,614
diabetes mellitus 3 | 1,663
esophageal adenocarcinoma 3 | 737
Acute lymphoid leukemia 2 | 25
Adenocarcinoma of pancreas 2 | 12
Atopic dermatitis 2 | 944
Atrial Fibrillation 2 | 110
Barrett's esophagus 2 | 185
Chronic myeloid leukemia 2 | 11
Degenerative polyarthritis 2 | 93
Epilepsy 2 | 346
Hb SS disease 2 | 2
Hemoglobin SS disease with crisis 2 | 2
IGA Glomerulonephritis 2 | 454
Malignant melanoma 2 | 2
Malignant tumor of head and/or neck 2 | 15
Malignant tumor of ovary 2 | 25
Metastatic Breast Carcinoma 2 | 21
Myocardial Ischemia 2 | 169
Neoplasm Invasiveness 2 | 127
Neurodegenerative disease 2 | 383
Polycystic Ovary Syndrome 2 | 334
Schistosomiasis 2 | 38
Vascular disease 2 | 281
cutaneous lupus erythematosus 2 | 1,056
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
lung carcinoma 2 | 2,844
non-small cell lung carcinoma 2 | 413
posterior fossa group A ependymoma 2 | 1,511
relapsing-remitting multiple sclerosis 2 | 18
Adenoma 1 | 165
Anemia 1 | 252
Anoxia 1 | 33
Chronic progressive external ophthalmoplegia 1 | 18
Congenital myasthenic syndrome 1 | 28
De Vaal's syndrome 1 | 1
Deafness 1 | 18
Disease Progression 1 | 125
Encephalitis 1 | 54
Gaucher disease type 1 1 | 171
Hypoglycemia 1 | 81
Kidney Diseases 1 | 86
Liver diseases 1 | 66
Mesothelioma 1 | 40
Neoplasm Metastasis 1 | 138
Neural Tube Defects 1 | 31
Neuropathy 1 | 210
Pellagra 1 | 25
Severe Combined Immunodeficiency 1 | 46
Toxic encephalopathy 1 | 131
Venous Thromboembolism 1 | 34
cystic fibrosis and chronic rhinosinusitis 1 | 213
gliosarcoma 1 | 19

Tissue

Blood and immune system 24 | 17,994
Cardiovascular System 24 | 17,957
Digestive Tract 24 | 18,472
Endocrine System 24 | 18,511
Female tissues 24 | 18,646
Liver and Pancreas 24 | 18,135
Male tissues 24 | 17,968
Nervous System 24 | 18,560
Respiratory system 24 | 17,483
Skin and soft tissues 24 | 18,114
Urinary Tract 24 | 18,443

Target Family

Kinase 12 | 634
Enzyme 9 | 4,146
Non-IDG 3 | 11,969

Reactome Pathway

Synthesis and interconversion ... 24 | 24
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate kinase 9 AK9 Tbio Kinase -0.95667 9.15 83
Nucleoside diphosphate kinase A NME1 Tbio Kinase -2.97569 843.2 611
CTP synthase 2 CTPS2 Tbio Enzyme -1.17585 13.6 120
Glutaredoxin-1 GLRX Tbio Non-IDG -2.62436 421.7 138
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.88469 86.4 226
Glutathione reductase, mitochondrial GSR Tclin Enzyme -2.98871 830.6 224
Adenylate kinase isoenzyme 1 AK1 Tchem Kinase -2.36310 203.9 358
Thioredoxin TXN Tchem Non-IDG -3.17972 1452.1 459
Thymidylate kinase DTYMK Tbio Kinase -2.02105 103.5 239
dCTP pyrophosphatase 1 DCTPP1 Tchem Enzyme -1.09293 12.4 67