Development Level

Tbio 11 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal retinal inner nuclear... 1 | 8
decreased total retina thickne... 1 | 17
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76

Disease

ovarian cancer 9 | 8,520
psoriasis 6 | 6,694
lung cancer 5 | 4,740
Carcinoma 4 | 11,493
Multiple myeloma 4 | 1,332
osteosarcoma 4 | 7,950
acute myeloid leukemia 3 | 783
breast carcinoma 3 | 1,638
medulloblastoma, large-cell 3 | 6,241
progressive supranuclear palsy 3 | 676
Anemia 2 | 365
Cancer 2 | 2,499
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Pick's disease 2 | 15
glioblastoma 2 | 5,792
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Alzheimer's disease 1 | 658
Anterior open-bite malocclusion 1 | 4
Astrocytoma, Pilocytic 1 | 3,081
Atopic dermatitis 1 | 952
Breast Neoplasms 1 | 445
Breast cancer 1 | 3,578
CPI 1 | 1
Chronic Lymphocytic Leukemia 1 | 262
Cleft Palate 1 | 271
Cleft Palate, Isolated, And Mental Retardation 1 | 2
Cleft Soft Palate 1 | 7
Cleft of hard palate 1 | 2
Cleft uvula 1 | 27
Deep overbite 1 | 4
Epilepsy 1 | 792
Familial cancer of breast 1 | 12
Gingival Hyperplasia 1 | 34
Gingival Hypertrophy 1 | 34
Gingival Overgrowth 1 | 36
Human immunodeficiency virus infectious disease 1 | 138
Hypoplastic mandible condyle 1 | 275
Intermediate coronary syndrome 1 | 11
Low tension glaucoma 1 | 7
Mandibular hypoplasia 1 | 275
Micrognathism 1 | 275
Myocardial Infarction 1 | 151
Neurocirculatory asthenia 1 | 2
Neurodegenerative disease 1 | 414
Ovarian Cysts 1 | 41
Overbite 1 | 4
Posterior lingual occlusion of mandibular teeth 1 | 4
Profound Mental Retardation 1 | 31
Profound intellectual disabilities 1 | 31
SPASTIC PARAPLEGIA 53, AUTOSOMAL RECESSIVE 1 | 1
Seizures 1 | 596
Submucous cleft of hard palate 1 | 11
Uranostaphyloschisis 1 | 167
Vascular disease 1 | 319
Williams-Beuren syndrome 1 | 50
adrenocortical carcinoma 1 | 1,428
adult high grade glioma 1 | 3,801
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
atypical teratoid / rhabdoid tumor 1 | 5,112
diabetes mellitus 1 | 1,728
ductal carcinoma in situ 1 | 1,745
ependymoma 1 | 4,679
fibroadenoma 1 | 559
group 3 medulloblastoma 1 | 4,104
group 4 medulloblastoma 1 | 1,855
head and neck cancer 1 | 271
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
non-small cell lung cancer 1 | 2,890
pancreatic cancer 1 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
primary open angle glaucoma 1 | 16
primary pancreatic ductal adenocarcinoma 1 | 1,109
primitive neuroectodermal tumor 1 | 3,035
spina bifida 1 | 1,074
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 1 | 4,145

Reactome Pathway

Synthesis And Processing Of GA... 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Glycylpeptide N-tetradecanoyltransferase 2 NMT2 Tchem Enzyme -1.21261 12.8 255
Vacuolar protein sorting-associated protein 28 homolog VPS28 Tbio Non-IDG -1.29153 15.5 110
Vacuolar protein sorting-associated protein 37D VPS37D Tdark Non-IDG 0.51 0.16 8
Ubiquitin-associated protein 1 UBAP1 Tbio Non-IDG -2.22105 163.3 130
Vacuolar protein sorting-associated protein 37A VPS37A Tbio Non-IDG -0.85697 9.69 80