Development Level

Tbio 12 | 11,445
Tchem 5 | 1,598
Tclin 2 | 613

IMPC Phenotype

increased circulating triglyce... 2 | 42
abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal lung morphology 1 | 26
abnormal retina morphology 1 | 71
cataract 1 | 92
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased lymphocyte cell numb... 1 | 83
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased neutrophil cell numb... 1 | 46
limb grasping 1 | 41
mydriasis 1 | 6
tremors 1 | 39

Disease

Carcinoma 15 | 11,493
glioblastoma 15 | 5,792
Cancer 14 | 2,499
osteosarcoma 14 | 7,950
ovarian cancer 13 | 8,520
lung carcinoma 12 | 2,843
medulloblastoma, large-cell 12 | 6,241
Breast cancer 11 | 3,578
atypical teratoid / rhabdoid tumor 10 | 5,112
malignant mesothelioma 10 | 3,232
Astrocytoma, Pilocytic 9 | 3,081
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
psoriasis 9 | 6,694
cystic fibrosis 8 | 1,696
ependymoma 8 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
lung cancer 7 | 4,740
primary pancreatic ductal adenocarcinoma 7 | 1,109
tuberculosis 7 | 2,010
Schizophrenia 6 | 1,160
adult high grade glioma 6 | 3,801
diabetes mellitus 6 | 1,728
interstitial cystitis 6 | 2,312
primitive neuroectodermal tumor 6 | 3,035
Gliosis 5 | 56
Vascular disease 5 | 319
nasopharyngeal carcinoma 5 | 1,058
ulcerative colitis 5 | 1,819
Arthritis 4 | 290
Down syndrome 4 | 499
Kidney cancer 4 | 2,613
Liver Cirrhosis 4 | 181
Liver Cirrhosis, Experimental 4 | 769
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
group 4 medulloblastoma 4 | 1,855
Atopic dermatitis 3 | 952
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Non-Small-Cell Lung 3 | 107
Cerebrovascular accident 3 | 63
Cerebrovascular disease 3 | 238
Cleft Palate 3 | 271
Coronary artery disease 3 | 268
Duchenne muscular dystrophy 3 | 601
Endometriosis 3 | 540
Glanzmann's thrombasthenia 3 | 23
Heart disease 3 | 306
Hydronephrosis 3 | 89
Hypersensitivity reaction type II disease 3 | 253
Kidney disease 3 | 430
Prenatal onset 3 | 139
Prostatic Neoplasms 3 | 495
Stroke 3 | 33
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cutaneous lupus erythematosus 3 | 1,057
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Abdomen distended 2 | 43
Anemia 2 | 365
Arthrogryposis 2 | 54
Congenital deafness 2 | 185
Deafness 2 | 198
Death in early childhood 2 | 82
Death in infancy 2 | 82
Dystrophia unguium 2 | 53
Gaucher disease type 1 2 | 180
Hearing Loss, Partial 2 | 185
Hemoglobin low 2 | 124
Inflammation 2 | 120
Kidney Diseases 2 | 114
Lung disease 2 | 142
Mood Disorders 2 | 184
Muscle Weakness 2 | 170
Nail dysplasia 2 | 52
Nausea and vomiting 2 | 97
Neoplasm Invasiveness 2 | 161
Neoplasm Metastasis 2 | 168
Osteoporosis 2 | 363
Polyhydramnios 2 | 108
Psychotic Disorders 2 | 151
RENAL ADYSPLASIA 2 | 25
Renal dysplasia 2 | 28
Reperfusion Injury 2 | 86
Thrombocytopenia 2 | 197
active ulcerative colitis 2 | 764
hearing impairment 2 | 199
posterior fossa group B ependymoma 2 | 416

Tissue

Blood and immune system 19 | 16,909
Cardiovascular System 19 | 15,192
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678

Target Family

Non-IDG 16 | 12,091
Kinase 2 | 634
Transcription Factor 1 | 1,400

Reactome Pathway

Syndecan interactions 19 | 19
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Syndecan-3 SDC3 Tbio Non-IDG -1.86172 78.8 179
Tenascin TNC Tbio Non-IDG -2.34421 216.5 642
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Integrin beta-4 ITGB4 Tbio Non-IDG -2.26591 177.4 704
Trafficking protein particle complex subunit 4 TRAPPC4 Tbio Non-IDG -0.87026 9.19 204
Syndecan-4 SDC4 Tbio Non-IDG -2.39649 274.8 297
Integrin alpha-6 ITGA6 Tbio Non-IDG -2.30127 180.4 944
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Thrombospondin-1 THBS1 Tbio Non-IDG -3.06622 1281.6 504
Integrin alpha-2 ITGA2 Tbio Non-IDG -2.58423 335.9 895