Development Level

Tclin 8 | 613
Tbio 7 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

decreased body weight 2 | 161
decreased total body fat amoun... 2 | 207
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
edema 1 | 59
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased startle reflex 1 | 112
preweaning lethality, complete... 1 | 979
tremors 1 | 39

Disease

Carcinoma 16 | 11,493
adult high grade glioma 13 | 3,801
glioblastoma 13 | 5,792
atypical teratoid / rhabdoid tumor 12 | 5,112
medulloblastoma, large-cell 12 | 6,241
Schizophrenia 10 | 1,160
ependymoma 10 | 4,679
osteosarcoma 10 | 7,950
Epilepsy 9 | 792
Kidney cancer 9 | 2,613
Bipolar Disorder 8 | 666
General anesthesia 8 | 53
Local anesthesia 8 | 40
ovarian cancer 8 | 8,520
primitive neuroectodermal tumor 8 | 3,035
Intellectual disability 7 | 1,016
Toxic encephalopathy 7 | 141
astrocytic glioma 7 | 2,597
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
psoriasis 7 | 6,694
subependymal giant cell astrocytoma 7 | 2,287
Astrocytoma, Pilocytic 6 | 3,081
Major Depressive Disorder 6 | 301
Parkinson's disease 6 | 392
Pick disease 6 | 1,894
lung cancer 6 | 4,740
Alcoholism 5 | 45
Alzheimer's disease 5 | 658
Arteriosclerotic Parkinsonism 5 | 8
Depressive disorder 5 | 409
Extrapyramidal disease 5 | 8
Influenza A Prevention 5 | 7
Influenza due to Influenza A virus 5 | 7
Lennox-Gastaut syndrome 5 | 34
Melanoma 5 | 711
Mental Depression 5 | 333
Parkinsonism 5 | 18
Postencephalitic parkinsonism 5 | 12
Simple partial seizure 5 | 26
Skin cancer 5 | 469
group 4 medulloblastoma 5 | 1,855
Autistic Disorder 4 | 364
Breast cancer 4 | 3,578
Dull intelligence 4 | 645
Liver cancer 4 | 604
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Poor school performance 4 | 645
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
malignant mesothelioma 4 | 3,232
Alcoholic Intoxication, Chronic 3 | 289
Amyotrophic lateral sclerosis 3 | 451
Cerebrovascular disease 3 | 238
Endometrial cancer 3 | 311
Epilepsy characterized by intractable complex partial seizures 3 | 28
Fragile X syndrome 3 | 34
Huntington's disease 3 | 76
Migraine Prevention 3 | 23
Moderate to Severe Alzheimer's Type Dementia 3 | 5
Mood Disorders 3 | 184
Partial seizure 3 | 15
Tonic-clonic epilepsy 3 | 47
Unipolar Depression 3 | 250
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
Abnormal behavior 2 | 52
Alcohol dependence 2 | 107
Attention deficit hyperactivity disorder 2 | 278
Autism Spectrum Disorders 2 | 75
Autism spectrum disorder 2 | 101
Brain Ischemia 2 | 110
Cocaine-Related Disorders 2 | 92
Cognitive delay 2 | 608
Colorectal Neoplasms 2 | 243
Delayed speech and language development 2 | 112
Dementia 2 | 175
Encephalitis 2 | 64
Highly variable severity 2 | 157
Hyperalgesia 2 | 83
Language Delay 2 | 112
Large intestine cancer 2 | 126
Mental and motor retardation 2 | 608
Morphine dependence 2 | 16
Neurodevelopmental Disorders 2 | 70
Seizures 2 | 596
Speech Delay 2 | 112
Speech impairment 2 | 112
Variable expressivity 2 | 157
Vascular disease 2 | 319
astrocytoma 2 | 1,146
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
ulcerative colitis 2 | 1,819

Tissue

Digestive Tract 20 | 17,369
Endocrine System 20 | 18,159
Nervous System 20 | 16,725
Skin and soft tissues 20 | 17,230
Blood and immune system 19 | 16,909
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Urinary Tract 18 | 16,678
Respiratory system 17 | 16,393
Cardiovascular System 15 | 15,192

Target Family

Non-IDG 9 | 12,091
Ion Channel 8 | 344
Enzyme 3 | 4,145

Reactome Pathway

Synaptic adhesion-like molecul... 20 | 20
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Reticulon-3 RTN3 Tbio Non-IDG -1.53823 40.0 137
Leucine-rich repeat and fibronectin type III domain-containing protein 1 LRFN1 Tdark Non-IDG -0.40499 2.43 58
Flotillin-1 FLOT1 Tbio Non-IDG -2.13455 128.8 277
Glutamate receptor ionotropic, NMDA 2A GRIN2A Tclin Ion Channel -3.09828 1158.1 555
Leucine-rich repeat and fibronectin type-III domain-containing protein 3 LRFN3 Tdark Non-IDG -0.48565 2.89 63
Glutamate receptor ionotropic, NMDA 2C GRIN2C Tclin Ion Channel -2.21470 153.6 208
Leucine-rich repeat and fibronectin type-III domain-containing protein 2 LRFN2 Tbio Non-IDG -0.81315 6.12 97
Glutamate receptor 4 GRIA4 Tclin Ion Channel -2.43418 256.1 326
Glutamate receptor ionotropic, NMDA 2D GRIN2D Tclin Ion Channel -2.11112 128.4 110
Glutamate receptor 1 GRIA1 Tclin Ion Channel -3.17077 1441.5 761