Development Level

Tbio 18 | 11,445
Tclin 8 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal lip morphology 1 | 2
convulsive seizures 1 | 13
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased fasted circulating g... 1 | 65
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating bilirubi... 1 | 16
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
pallor 1 | 34
short tibia 1 | 97

Disease

Carcinoma 17 | 11,493
lung cancer 17 | 4,740
non-small cell lung cancer 15 | 2,890
ovarian cancer 14 | 8,520
lung adenocarcinoma 13 | 2,716
lung carcinoma 13 | 2,843
osteosarcoma 10 | 7,950
malignant mesothelioma 8 | 3,232
Pulmonary alveolar proteinosis 7 | 15
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
invasive ductal carcinoma 7 | 2,951
medulloblastoma, large-cell 7 | 6,241
psoriasis 7 | 6,694
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Asthma 5 | 385
Autosomal recessive predisposition 5 | 1,442
adrenocortical carcinoma 5 | 1,428
tuberculosis 5 | 2,010
ulcerative colitis 5 | 1,819
Acute exacerbation of asthma 4 | 14
Asthma management 4 | 19
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Bronchitis 4 | 43
Dyspnea 4 | 76
Nasal congestion 4 | 21
Nasal discharge 4 | 24
Pneumonia 4 | 174
Pulmonary emphysema 4 | 48
Schizophrenia 4 | 1,160
Spasticity 4 | 26
adult high grade glioma 4 | 3,801
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
esophageal adenocarcinoma 4 | 737
group 3 medulloblastoma 4 | 4,104
pancreatic cancer 4 | 2,398
Amyotrophic lateral sclerosis type 3 3 | 17
Ankylosing spondylitis 3 | 140
Cancer 3 | 2,499
Congenital diaphragmatic hernia 3 | 67
Diaphragmatic Hernia 3 | 40
Failure to gain weight 3 | 365
Hernia, Diaphragmatic 3 | 40
Idiopathic pulmonary fibrosis 3 | 23
Lung Neoplasms 3 | 232
Lung disease 3 | 142
Mood Disorders 3 | 184
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Peripheral vascular disease 3 | 87
Pulmonary Fibrosis, Idiopathic 3 | 12
Pulmonary alveolar microlithiasis 3 | 4
Respiratory Failure 3 | 104
Surfactant Metabolism Dysfunction, Pulmonary, 1 3 | 3
Vascular disease 3 | 319
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
dermatomyositis 3 | 966
facioscapulohumeral dystrophy 3 | 288
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
interstitial lung disease 3 | 298
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
urothelial carcinoma 3 | 318
Adenocarcinoma of lung (disorder) 2 | 60
Administration of Local Anesthetic Nerve Block 2 | 14
Adverse reaction to drug 2 | 61
Barrett's esophagus 2 | 182
Bronchiectasis 2 | 64
Cardiomegaly 2 | 116
Cerebral Ischemia 2 | 37
Clubbing 2 | 9
Common cold 2 | 67
Cyanosis 2 | 17
Drug-Related Side Effects and Adverse Reactions 2 | 62
Fibrosis 2 | 44
Gilles de la Tourette syndrome 2 | 47
Hyperphosphatemia 2 | 32
Hypertensive Emergencies 2 | 10
Hypertensive disorder 2 | 56
Hypophosphatemia 2 | 40
Hypotension 2 | 82
Idiopathic pulmonary arterial hypertension 2 | 40
Local anesthesia, by infiltration 2 | 14
Ocular hypertension 2 | 42
Open-angle glaucoma 2 | 27
Pain 2 | 103
Panic disorder 2 | 61
Pheochromocytoma 2 | 24
Pulmonary hypertension 2 | 85
Respiratory distress 2 | 43
Sepsis 2 | 24

Tissue

Digestive Tract 28 | 17,369
Endocrine System 27 | 18,159
Male tissues 27 | 17,142
Respiratory system 27 | 16,393
Skin and soft tissues 27 | 17,230
Blood and immune system 26 | 16,909
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Nervous System 26 | 16,725
Urinary Tract 26 | 16,678
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145
GPCR 6 | 408
Transcription Factor 2 | 1,400
Transporter 2 | 473

Reactome Pathway

Surfactant metabolism 28 | 28
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Palmitoyltransferase ZDHHC2 ZDHHC2 Tbio Enzyme -1.91418 79.6 82
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
Cytoskeleton-associated protein 4 CKAP4 Tbio Non-IDG -1.45279 28.4 190
Pulmonary surfactant-associated protein A1 SFTPA1 Tbio Non-IDG -2.05283 109.3 228
Adhesion G protein-coupled receptor F5 ADGRF5 Tbio GPCR -0.93250 10.8 161
Pulmonary surfactant-associated protein D SFTPD Tbio Non-IDG -2.81488 698.4 291
Pepsin A-4 PGA4 Tbio Enzyme -1.47130 28.5 118
Pepsin A-3 PGA3 Tbio Enzyme -1.47858 28.8 123
Pepsin A-5 PGA5 Tclin Enzyme -1.97335 91.2 100
Alpha-2A adrenergic receptor ADRA2A Tclin GPCR -2.42160 261.4 232