Development Level

Tbio 9 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

abnormal sleep behavior 2 | 70
preweaning lethality, incomple... 2 | 499
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal iris transilluminatio... 1 | 2
abnormal retina morphology 1 | 71
decreased circulating glucose ... 1 | 126
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
enlarged thymus 1 | 5
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating sodium l... 1 | 71
increased startle reflex 1 | 112

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 8 | 6,241
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
adult high grade glioma 6 | 3,801
group 3 medulloblastoma 6 | 4,104
osteosarcoma 6 | 7,950
pituitary cancer 6 | 1,972
oligodendroglioma 5 | 2,850
ovarian cancer 5 | 8,519
primitive neuroectodermal tumor 5 | 3,035
Brain Ischemia 4 | 110
Kidney cancer 4 | 2,613
Astrocytoma, Pilocytic 3 | 3,081
Schnyder Corneal Dystrophy 3 | 23
astrocytic glioma 3 | 2,597
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
subependymal giant cell astrocytoma 3 | 2,287
Breast cancer 2 | 3,577
Oculocutaneous albinism 2 | 29
Seizures 2 | 596
Status Epilepticus 2 | 98
aldosterone-producing adenoma 2 | 665
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,695
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,290
lung adenocarcinoma 2 | 2,716
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pancreatic carcinoma 2 | 562
tuberculosis 2 | 2,010
Abnormality of macular pigmentation 1 | 16
Achromatopsia 1 | 16
Adenoid Cystic Carcinoma 1 | 99
Amelogenesis Imperfecta hypomaturation type 1 | 7
Amelogenesis imperfecta 1 | 29
Atherosclerosis 1 | 291
Brain cancer 1 | 30
COPD 1 | 118
Cancer 1 | 2,499
Carcinoma, Adenoid Cystic 1 | 99
Celiac disease 1 | 116
Central pontine myelinolysis 1 | 5
Chediak-Higashi syndrome 1 | 26
Congenital stationary night blindness 1 | 29
Congenital stationary night blindness 1B 1 | 6
Dementia 1 | 175
Difficulties with night vision 1 | 87
Globe disease 1 | 67
Heart conduction disease 1 | 83
Heart disease 1 | 306
Hereditary spastic paraplegia 24 1 | 2
Hermansky-Pudlak syndrome 1 | 42
Hypertension 1 | 396
Hypoplasia of optic disc 1 | 12
Liver Cirrhosis, Experimental 1 | 769
Macular pigmentary changes 1 | 16
Malaria 1 | 160
Malignant glioma 1 | 26
Megacolon 1 | 29
Melanoma 1 | 711
Multiple Sclerosis 1 | 540
Myocardial Ischemia 1 | 169
Myocardial Reperfusion Injury 1 | 37
Night Blindness 1 | 101
Night blindness, congenital stationary 1 | 16
Ocular albinism 1 | 26
Pick disease 1 | 1,894
Podoconiosis 1 | 5
Posterior polymorphous corneal dystrophy 1 | 19
Reduced visual acuity 1 | 63
Rosacea 1 | 25
Salivary Gland Neoplasms 1 | 46
Severe myopia 1 | 22
Skin cancer 1 | 469
Skin-Hair-Eye Pigmentation, Variation In, 4 1 | 1
Swine influenza 1 | 8
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
cystic fibrosis and chronic rhinosinusitis 1 | 214
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 459
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 270
hereditary spastic paraplegia 30 1 | 2
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,954
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
medulloblastoma 1 | 720
pediatric high grade glioma 1 | 1,064
primary pancreatic ductal adenocarcinoma 1 | 1,108
psoriasis 1 | 6,694
ulcerative colitis 1 | 1,819

Tissue

Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Blood and immune system 9 | 16,909
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Digestive Tract 8 | 17,369
Respiratory system 8 | 16,393
Cardiovascular System 7 | 15,192

Target Family

Transporter 9 | 473
Non-IDG 1 | 12,091

Reactome Pathway

Sodium/Calcium exchangers 10 | 10
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.63611 43.9 61
Sodium/calcium exchanger 3 SLC8A3 Tbio Transporter -1.87170 72.3 128
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.32054 20.8 63
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.70924 45.0 59
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.12274 13.0 86
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.52990 349.1 141
Mitochondrial sodium/calcium exchanger protein SLC8B1 Tbio Transporter -1.53269 33.9 58
Sodium/potassium/calcium exchanger 1 SLC24A1 Tbio Transporter -1.90810 81.5 92