Development Level

Tbio 9 | 10,625
Tchem 1 | 1,890

IMPC Term

increased circulating sodium l... 2 | 71
abnormal coat appearance 1 | 25
abnormal coat/hair pigmentatio... 1 | 54
abnormal iris transilluminatio... 1 | 1
abnormal retina morphology 1 | 100
abnormal retinal pigmentation 1 | 61
decreased circulating glucose ... 1 | 121
decreased fasted circulating g... 1 | 49
decreased prepulse inhibition 1 | 52
decreased rib number 1 | 59
enlarged thymus 1 | 4
impaired righting response 1 | 19
increased circulating HDL chol... 1 | 63
increased circulating alkaline... 1 | 119
increased circulating choleste... 1 | 53
increased grip strength 1 | 83
increased startle reflex 1 | 38
preweaning lethality, incomple... 1 | 260

Disease

medulloblastoma, large-cell 8 | 6,234
glioblastoma 7 | 5,572
osteosarcoma 6 | 7,933
pediatric high grade glioma 6 | 2,712
pituitary cancer 6 | 1,972
Brain Ischemia 5 | 87
atypical teratoid / rhabdoid tumor 5 | 4,369
ependymoma 5 | 2,514
oligodendroglioma 5 | 2,849
ovarian cancer 5 | 8,484
primitive neuroectodermal tumor 5 | 3,031
Carcinoma 3 | 2,147
Schnyder corneal dystrophy 3 | 23
astrocytic glioma 3 | 2,241
group 4 medulloblastoma 3 | 1,875
lung cancer 3 | 4,466
lung carcinoma 3 | 2,844
pancreatic cancer 3 | 2,300
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
Breast cancer 2 | 3,094
Oculocutaneous albinism 2 | 27
Seizures 2 | 95
Status Epilepticus 2 | 85
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,713
medulloblastoma 2 | 1,524
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung cancer 2 | 2,798
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087
AMELOGENESIS IMPERFECTA, HYPOMATURATION TYPE, IIA5 1 | 1
Achromatopsia 1 | 14
Adenoid Cystic Carcinoma 1 | 99
Alzheimer's disease 1 | 644
Amelogenesis Imperfecta hypomaturation type 1 | 5
Amelogenesis Imperfecta, Type III 1 | 3
Amelogenesis imperfecta 1 | 26
Asthma 1 | 349
Atherosclerosis 1 | 275
COPD 1 | 113
Cancer 1 | 2,346
Celiac disease 1 | 112
Central pontine myelinolysis 1 | 5
Charcot-Marie-Tooth disease type 4 1 | 10
Chediak-Higashi syndrome 1 | 24
Congenital stationary night blindness 1 | 27
Dementia 1 | 129
Globe disease 1 | 57
Heart conduction disease 1 | 65
Heart disease 1 | 279
Hermansky-Pudlak syndrome 1 | 43
Hydrolethalus syndrome 1 | 128
Hypertension 1 | 287
Megacolon 1 | 3
Multiple Sclerosis 1 | 498
Multiple myeloma 1 | 1,327
Myocardial Ischemia 1 | 169
Myocardial Reperfusion Injury 1 | 34
NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1D 1 | 1
Night blindness, congenital stationary 1 | 14
Obesity 1 | 616
Ocular albinism 1 | 29
Pick disease 1 | 1,893
Podoconiosis 1 | 5
Posterior polymorphous corneal dystrophy 1 | 24
Psychotic Disorders 1 | 20
Rosacea 1 | 18
Salivary Gland Neoplasms 1 | 45
Skin/Hair/Eye Pigmentation, Variation In, 4 1 | 1
Swine influenza 1 | 9
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 918
acute myeloid leukemia 1 | 780
adult high grade glioma 1 | 2,148
astrocytoma 1 | 1,493
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,665
cystic fibrosis and chronic rhinosinusitis 1 | 213
dermatomyositis 1 | 933
ductal carcinoma in situ 1 | 1,745
esophageal adenocarcinoma 1 | 737
gastric cancer 1 | 430
glioblastoma multiforme 1 | 347
group 3 medulloblastoma 1 | 2,254
head and neck cancer 1 | 270
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,988
primary pancreatic ductal adenocarcinoma 1 | 1,271
psoriasis 1 | 6,685

Tissue

Blood and immune system 10 | 17,995
Cardiovascular System 10 | 17,958
Digestive Tract 10 | 18,473
Endocrine System 10 | 18,512
Female tissues 10 | 18,647
Liver and Pancreas 10 | 18,136
Male tissues 10 | 17,969
Nervous System 10 | 18,561
Respiratory system 10 | 17,484
Skin and soft tissues 10 | 18,115
Urinary Tract 10 | 18,444

Target Family

Transporter 9 | 473
Non-IDG 1 | 11,971

Reactome Pathway

Sodium/Calcium exchangers 10 | 10
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Sodium/potassium/calcium exchanger 5 SLC24A5 Tbio Transporter -1.58874 38.9 49
Sorcin SRI Tbio Non-IDG -2.68021 468.2 104
Sodium/potassium/calcium exchanger 3 SLC24A3 Tbio Transporter -1.00648 8.98 76
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.20780 17.8 34
Sodium/potassium/calcium exchanger 4 SLC24A4 Tbio Transporter -1.19063 17.1 55
Sodium/calcium exchanger 3 SLC8A3 Tbio Transporter -1.68343 53.3 118
Sodium/potassium/calcium exchanger 6, mitochondrial SLC8B1 Tbio Transporter -1.21747 19.7 50
Sodium/calcium exchanger 1 SLC8A1 Tchem Transporter -2.35868 236.4 122
Sodium/potassium/calcium exchanger 1 SLC24A1 Tbio Transporter -1.76565 57.1 87