Development Level

Tbio 2 | 11,651
Tchem 1 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Carcinoma 3 | 11,493
Absence of pain sensation 2 | 5
Acral ulceration and osteomyelitis leading to autoamputation 2 | 4
Alzheimer's disease 2 | 658
Anhidrosis 2 | 23
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Congenital Pain Insensitivity 2 | 6
Corneal Ulcer 2 | 21
Hereditary Sensory Autonomic Neuropathy, Type 5 2 | 5
Hereditary Sensory and Autonomic Neuropathies 2 | 4
Hyperactive behavior 2 | 91
Infantile onset 2 | 238
Intellectual disability 2 | 1,016
Lewy Body Disease 2 | 21
Lung Injury 2 | 20
Neuropathy 2 | 261
Parkinson's disease 2 | 392
Schizophrenia 2 | 1,160
Self Mutilation 2 | 14
Skin Ulcer 2 | 48
Toxic encephalopathy 2 | 141
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Abnormal dermatoglyphic pattern 1 | 24
Alcohol withdrawal syndrome 1 | 20
Amnesia 1 | 17
Atrial Septal Defects 1 | 85
Autoimmune hepatitis 1 | 11
Autonomic nervous system disorders 1 | 19
Bleeding tendency 1 | 37
Brain disease 1 | 96
Cloudy cornea 1 | 33
Coarse hair 1 | 31
Complex regional pain syndrome 1 | 12
Congenital pectus carinatum 1 | 52
Corneal Scar 1 | 7
Corneal stromal opacities 1 | 33
Curly hair (finding) 1 | 14
Decreased number of small peripheral myelinated nerve fibers 1 | 1
Decreased pain sensation 1 | 17
Decreased projection of midface 1 | 105
Dysautonomia 1 | 20
Enlarged thorax 1 | 18
Familial medullary thyroid carcinoma 1 | 3
Full lower lip 1 | 64
Glioma 1 | 74
Glomerulonephritis 1 | 46
HSAN Type IV 1 | 1
Hepatitis 1 | 67
Hepatitis C 1 | 94
Hereditary insensitivity to pain with anhidrosis 1 | 1
Heroin dependence 1 | 30
Human immunodeficiency virus infectious disease 1 | 138
Hyperkeratosis 1 | 50
Hyperkinesis 1 | 32
Hypogonadism, Isolated Hypogonadotropic 1 | 71
Hypogonadotropic hypogonadism 1 | 89
Hypotrichosis of the scalp 1 | 6
Hypotrophic midface 1 | 105
Infarction, Middle Cerebral Artery 1 | 33
Infection of bone 1 | 19
Intermittent fever 1 | 15
Irritation - emotion 1 | 68
Kidney Failure, Chronic 1 | 46
Low posterior hairline 1 | 52
Lymphoid leukemia 1 | 160
Medullary carcinoma of thyroid 1 | 2
Midface retrusion 1 | 105
Mood swings 1 | 77
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Neurogenic arthropathy 1 | 2
Neurotrophic keratitis 1 | 2
Noonan syndrome 1 | 34
Papillary thyroid carcinoma 1 | 43
Parkinsonian Disorders 1 | 56
Peripheral Neuropathy 1 | 134
Phaeochromocytoma 1 | 20
Polyneuropathy 1 | 64
Postural hypotension with compensatory tachycardia 1 | 2
Prominent lower lip 1 | 64
Pulmonary Stenosis 1 | 45
Pulmonary artery stenosis 1 | 26
Relative macrocephaly 1 | 12
Rhinitis 1 | 55
Rough hair texture 1 | 31
Self-Injurious Behavior 1 | 12
Small midface 1 | 105
Syphilis 1 | 17
Tetanus 1 | 68
Wide spaced nipples 1 | 46
interstitial lung disease 1 | 298

Tissue

Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Nervous System 4 | 16,725
Skin and soft tissues 4 | 17,230
Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Respiratory system 3 | 16,393
Urinary Tract 3 | 16,678

Target Family

Enzyme 2 | 4,145
Kinase 1 | 634
Non-IDG 1 | 12,091

Reactome Pathway

Signalling to p38 via RIT and ... 4 | 4
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTP-binding protein Rit1 RIT1 Tbio Enzyme -2.22794 163.1 197
High affinity nerve growth factor receptor NTRK1 Tclin Kinase -3.05841 1050.9 1092
Beta-nerve growth factor NGF Tchem Non-IDG -4.01592 10936.7 735
GTP-binding protein Rit2 RIT2 Tbio Enzyme -2.89394 791.7 163