Development Level

Tbio 22 | 10,625
Tchem 10 | 1,890
Tclin 9 | 602
Tdark 1 | 7,003

IMPC Term

abnormal bone mineralization 1 | 55
abnormal testis morphology 1 | 30
decreased mean corpuscular vol... 1 | 50
decreased thermal nociceptive ... 1 | 4
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased circulating potassiu... 1 | 31
increased circulating triglyce... 1 | 24
small testis 1 | 37

Disease

psoriasis 22 | 6,685
osteosarcoma 19 | 7,933
ovarian cancer 19 | 8,492
medulloblastoma, large-cell 17 | 6,234
glioblastoma 14 | 5,572
Cancer 13 | 2,346
lung cancer 13 | 4,473
lung carcinoma 13 | 2,844
pituitary cancer 13 | 1,972
invasive ductal carcinoma 12 | 2,950
ductal carcinoma in situ 10 | 1,745
ependymoma 9 | 2,514
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,795
pilocytic astrocytoma 9 | 3,086
breast carcinoma 8 | 1,614
cystic fibrosis 8 | 1,670
fibroadenoma 8 | 557
interstitial cystitis 8 | 2,299
lung adenocarcinoma 8 | 2,714
malignant mesothelioma 8 | 3,163
non-small cell lung cancer 8 | 2,798
oligodendroglioma 8 | 2,849
Kaposi's Sarcoma Skin Lesions 7 | 7
Obesity 7 | 616
active Crohn's disease 7 | 918
astrocytic glioma 7 | 2,241
atypical teratoid / rhabdoid tumor 7 | 4,369
Breast cancer 6 | 3,099
Myocardial Ischemia 6 | 169
astrocytoma 6 | 1,493
colon cancer 6 | 1,475
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
nasopharyngeal carcinoma 6 | 1,056
pediatric high grade glioma 6 | 2,712
spina bifida 6 | 1,064
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 2,087
Endometriosis 5 | 535
Leigh disease 5 | 81
Stomach Neoplasms 5 | 282
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
adult high grade glioma 5 | 2,148
group 3 medulloblastoma 5 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
pancreatic cancer 5 | 2,300
Acne vulgaris 4 | 16
Acute promyelocytic leukemia, FAB M3 4 | 10
Alcohol dependence 4 | 107
Atopic dermatitis 4 | 944
Chloasma 4 | 5
Facial Fine Wrinkling 4 | 4
Fine Wrinkling 4 | 4
Hyperkeratosis 4 | 4
Lactic acidosis 4 | 43
Mammary Neoplasms 4 | 410
Mottle Hyperpigmentation 4 | 4
Multiple myeloma 4 | 1,328
Pick disease 4 | 1,893
Prostatic Neoplasms 4 | 471
Pyruvate decarboxylase deficiency 4 | 15
Severe Recalcitrant Nodular Acne 4 | 4
Solar Lentigines 4 | 5
aldosterone-producing adenoma 4 | 664
primary pancreatic ductal adenocarcinoma 4 | 1,271
primitive neuroectodermal tumor 4 | 3,031
Benign Facial Lentigine 3 | 3
Diabetes Mellitus, Experimental 3 | 106
Facial Hyperpigmentation 3 | 3
Facial Hypopigmentation 3 | 3
Liver disease 3 | 219
Peripheral Neuropathy 3 | 303
Primary cutaneous T-cell lymphoma 3 | 29
Renal Cell Carcinoma 3 | 199
Sciatic Neuropathy 3 | 5
active ulcerative colitis 3 | 477
acute myeloid leukemia 3 | 785
atypical teratoid/rhabdoid tumor 3 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic rhinosinusitis 3 | 512
cystic fibrosis and chronic rhinosinusitis 3 | 213
dermatomyositis 3 | 967
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 436
hereditary spastic paraplegia 3 | 313
juvenile dermatomyositis 3 | 1,189
medulloblastoma 3 | 1,524
mucosa-associated lymphoid tissue lymphoma 3 | 480
posterior fossa group A ependymoma 3 | 1,511
posterior fossa group B ependymoma 3 | 1,530
tuberculosis 3 | 1,563
head and neck cancer 2 | 270
inflammatory breast cancer 2 | 404
nephrosclerosis 2 | 329
pancreatic carcinoma 2 | 567
pterygium 2 | 74
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 42 | 17,995
Cardiovascular System 42 | 17,958
Digestive Tract 42 | 18,473
Endocrine System 42 | 18,512
Female tissues 42 | 18,647
Liver and Pancreas 42 | 18,136
Male tissues 42 | 17,969
Nervous System 42 | 18,561
Respiratory system 42 | 17,484
Skin and soft tissues 42 | 18,115
Urinary Tract 42 | 18,444

Target Family

Enzyme 26 | 4,146
Nuclear Receptor 7 | 48
Non-IDG 5 | 11,969
Kinase 4 | 634

Reactome Pathway

Signaling by Retinoic Acid 42 | 42
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fatty acid-binding protein, epidermal FABP5 Tchem Non-IDG -1.89658 125.5 197
Dehydrogenase/reductase SDR family member 4 DHRS4 Tbio Enzyme -1.63183 43.7 106
Cytochrome P450 26A1 CYP26A1 Tclin Enzyme -2.43017 287.7 162
Retinal dehydrogenase 2 ALDH1A2 Tchem Enzyme -2.23286 171.4 208
Retinol dehydrogenase 14 RDH14 Tbio Enzyme -0.13566 1.01 32
Cellular retinoic acid-binding protein 1 CRABP1 Tbio Non-IDG -2.47720 302.5 122
Carnitine O-palmitoyltransferase 1, liver isoform CPT1A Tchem Enzyme -2.33829 203.2 252
Retinal dehydrogenase 1 ALDH1A1 Tchem Enzyme -2.76440 583.4 632
Alcohol dehydrogenase 1C ADH1C Tclin Enzyme -2.40789 366.0 73
Retinoic acid receptor gamma RARG Tclin Nuclear Receptor -2.11295 117.2 123