Development Level

Tbio 13 | 10,625
Tchem 7 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

Disease

ovarian cancer 18 | 8,484
osteosarcoma 14 | 7,933
psoriasis 11 | 6,685
medulloblastoma, large-cell 10 | 6,234
Cancer 9 | 2,346
invasive ductal carcinoma 9 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
glioblastoma 7 | 5,572
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
lung adenocarcinoma 7 | 2,713
pancreatic cancer 7 | 2,300
spina bifida 7 | 1,064
Breast cancer 6 | 3,094
Pick disease 6 | 1,893
atypical teratoid / rhabdoid tumor 6 | 4,369
breast carcinoma 6 | 1,614
group 4 medulloblastoma 6 | 1,875
juvenile dermatomyositis 6 | 1,189
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,271
Amyotrophic Lateral Sclerosis 5 | 431
dermatomyositis 5 | 933
lung carcinoma 5 | 2,844
malignant mesothelioma 5 | 3,162
subependymal giant cell astrocytoma 5 | 2,287
Down syndrome 4 | 548
Rheumatoid Arthritis 4 | 1,160
acute quadriplegic myopathy 4 | 1,157
astrocytoma 4 | 1,493
ductal carcinoma in situ 4 | 1,745
interstitial cystitis 4 | 2,299
lung cancer 4 | 4,466
primitive neuroectodermal tumor 4 | 3,031
Cerebrovascular disease 3 | 231
colon cancer 3 | 1,475
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
glioblastoma multiforme 3 | 347
group 3 medulloblastoma 3 | 2,254
medulloblastoma 3 | 1,524
non-small cell lung cancer 3 | 2,798
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
Alzheimer's disease 2 | 644
Carcinoma 2 | 2,147
Cholestasis 2 | 93
Diabetic Retinopathy 2 | 53
Epithelioid hemangioendothelioma 2 | 5
Inflammatory bowel disease 2 | 142
Kidney disease 2 | 396
Multiple myeloma 2 | 1,327
Parkinson's disease 2 | 364
active Crohn's disease 2 | 918
active ulcerative colitis 2 | 477
adult high grade glioma 2 | 2,148
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
posterior fossa group A ependymoma 2 | 1,511
posterior fossa group B ependymoma 2 | 1,530
sonic hedgehog group medulloblastoma 2 | 1,482
ulcerative colitis 2 | 2,087
Brain disease 1 | 83
Cerebral artery occlusion 1 | 3
Ciliopathy 1 | 57
Corneal disease 1 | 32
Dementia 1 | 129
Diabetes Mellitus, Experimental 1 | 106
Histiocytoid hemangioma 1 | 3
Huntington's disease 1 | 72
Irritable bowel syndrome 1 | 59
Leber congenital amaurosis 1 | 72
Lissencephaly 1 | 61
Liver disease 1 | 219
Muscular atrophy 1 | 67
Myopathy 1 | 128
Neoplasm Metastasis 1 | 138
Nerve Degeneration 1 | 73
Neuroblastoma 1 | 78
Neurodegenerative disease 1 | 383
Neuropathy 1 | 210
Prion disease 1 | 10
Refractive Errors 1 | 18
Renal Cell Carcinoma 1 | 199
Retinal Degeneration 1 | 49
Retinitis pigmentosa 1 | 153
Status Epilepticus 1 | 85
Toxic encephalopathy 1 | 131
atypical teratoid/rhabdoid tumor 1 | 1,095
cone-rod dystrophy 1 | 56
hereditary spastic paraplegia 1 | 313
interstitial lung disease 1 | 291
limb girdle muscular dystrophy 2A 1 | 156
nervous system disorder 1 | 53
non-inflammatory breast cancer 1 | 208
ovarian neoplasm 1 | 97
post-traumatic stress disorder 1 | 45
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 20 | 17,995
Cardiovascular System 20 | 17,958
Digestive Tract 20 | 18,473
Endocrine System 20 | 18,512
Female tissues 20 | 18,647
Liver and Pancreas 20 | 18,136
Male tissues 20 | 17,969
Nervous System 20 | 18,561
Respiratory system 20 | 17,484
Skin and soft tissues 20 | 18,115
Urinary Tract 20 | 18,444

Target Family

Non-IDG 13 | 11,971
Kinase 4 | 634
Enzyme 3 | 4,146

Reactome Pathway

Signaling by Hippo 20 | 20
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein KIBRA WWC1 Tbio Non-IDG -1.88892 84.4 96
Nephrocystin-4 NPHP4 Tbio Non-IDG -1.39275 26.0 48
14-3-3 protein epsilon YWHAE Tchem Non-IDG -2.18406 158.6 309
Caspase-3 CASP3 Tchem Enzyme -4.25532 16628.4 1445
14-3-3 protein beta/alpha YWHAB Tchem Non-IDG -2.02614 102.4 440
MOB kinase activator 1B MOB1B Tbio Enzyme -0.75722 4.89 195
Serine/threonine-protein kinase LATS1 LATS1 Tbio Kinase -2.20073 158.3 217
Tight junction protein ZO-1 TJP1 Tbio Non-IDG -3.14176 1243.9 230
Angiomotin-like protein 1 AMOTL1 Tbio Non-IDG -1.12782 13.1 71
Protein salvador homolog 1 SAV1 Tbio Non-IDG -1.78582 63.3 135