Development Level

Tbio 6 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal femur morphology 1 | 14
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased lean body mass 1 | 172
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

osteosarcoma 11 | 7,950
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
Cancer 7 | 2,499
Carcinoma 7 | 11,493
glioblastoma 6 | 5,792
adult high grade glioma 5 | 3,801
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
psoriasis 5 | 6,694
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Breast cancer 4 | 3,578
Schizophrenia 4 | 1,160
atypical teratoid / rhabdoid tumor 4 | 5,112
group 4 medulloblastoma 4 | 1,855
oligodendroglioma 4 | 2,850
Kidney cancer 3 | 2,613
Pick disease 3 | 1,894
astrocytoma 3 | 1,146
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
mucosa-associated lymphoid tissue lymphoma 3 | 484
primitive neuroectodermal tumor 3 | 3,035
Astrocytoma, Pilocytic 2 | 3,081
Carcinoma, Squamous Cell 2 | 110
Composite lymphoma 2 | 3
Hemolytic anemia 2 | 77
Liver Cirrhosis, Experimental 2 | 769
Neoplasm Invasiveness 2 | 161
Noonan syndrome 2 | 34
Osteopetrosis 2 | 43
Rheumatoid arthritis 2 | 1,191
Squamous cell carcinoma 2 | 129
Status Epilepticus 2 | 98
Type 1 diabetes mellitus 2 | 109
Vascular disease 2 | 319
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
pancreatic cancer 2 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
ulcerative colitis 2 | 1,819
Acquired cubitus valgus 1 | 18
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Apraxias 1 | 27
Arthropathy 1 | 43
Basal ganglia calcification 1 | 27
Birthmark 1 | 35
Blastic phase chronic myeloid leukemia 1 | 58
Bundle-Branch Block 1 | 8
Cafe-au-Lait Spots 1 | 37
Cardiofaciocutaneous syndrome 1 | 15
Cell Transformation, Neoplastic 1 | 97
Central sleep apnea 1 | 11
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Congenital pectus carinatum 1 | 52
Enlarged thorax 1 | 18
Factor XII deficiency 1 | 13
Full lower lip 1 | 64
Hand deformities 1 | 32
Heart Valve Diseases 1 | 25
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Increased gastric cancer 1 | 21
Irritation - emotion 1 | 68
LEOPARD syndrome 1 | 20
Leiomyosarcoma of uterus 1 | 13
Limited elbow movement 1 | 6
Malignant peripheral nerve sheath tumor 1 | 12
Mild Mental Retardation 1 | 70
Neoplastic Cell Transformation 1 | 89
Neurofibromatosis 1 | 40
Ollier disease 1 | 18
Polycystic Kidney, Autosomal Recessive 1 | 9
Postnatal growth retardation 1 | 57
Primitive reflexes (palmomental, snout, glabellar) 1 | 7
Prominent lower lip 1 | 64
Pulmonary valve stenosis 1 | 9
Scapular weakness 1 | 23
Skin Neoplasms 1 | 69
Synovitis 1 | 78
Transitional cell carcinoma of bladder 1 | 17
Wide spaced nipples 1 | 46
Winged scapula 1 | 23

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 4 | 12,091
Kinase 3 | 634

Reactome Pathway

Signal regulatory protein fami... 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal-regulatory protein beta-1 isoform 3 SIRPB1 Tbio Non-IDG -0.77740 8.38 192
Focal adhesion kinase 1 PTK2 Tchem Kinase -3.06733 1038.3 2013
Src kinase-associated phosphoprotein 2 SKAP2 Tbio Enzyme -2.76447 571.7 170
TYRO protein tyrosine kinase-binding protein TYROBP Tbio Enzyme -2.32694 213.9 206
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Tyrosine-protein phosphatase non-receptor type substrate 1 SIRPA Tbio Enzyme -2.64055 449.1 611
Tyrosine-protein phosphatase non-receptor type 6 PTPN6 Tchem Enzyme -2.14628 178.2 684
Signal-regulatory protein beta-1 SIRPB1 Tbio Non-IDG -0.77740 8.38 192