Development Level

Tbio 24 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

cataract 1 | 92
decreased grip strength 1 | 116

Disease

Carcinoma 21 | 11,493
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
osteosarcoma 12 | 7,950
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
psoriasis 9 | 6,694
Astrocytoma, Pilocytic 8 | 3,081
Autosomal recessive predisposition 8 | 1,442
interstitial cystitis 8 | 2,312
Breast cancer 7 | 3,578
Intellectual disability 7 | 1,016
group 3 medulloblastoma 7 | 4,104
invasive ductal carcinoma 7 | 2,951
lung cancer 7 | 4,740
lung carcinoma 7 | 2,843
Coarse facial features 6 | 108
Epilepsy 6 | 792
Kidney cancer 6 | 2,613
Thickened facial skin with coarse facial features 6 | 108
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
lung adenocarcinoma 6 | 2,716
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
ulcerative colitis 6 | 1,819
Dull intelligence 5 | 645
Glycoproteinosis 5 | 12
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Multiple myeloma 5 | 1,332
Poor school performance 5 | 645
Schizophrenia 5 | 1,160
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
oligodendroglioma 5 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pituitary cancer 5 | 1,972
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Cancer 4 | 2,499
Cerebellar Ataxia 4 | 304
Hepatomegaly 4 | 285
Muscle hypotonia 4 | 571
Seizures 4 | 596
Splenomegaly 4 | 190
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
astrocytoma 4 | 1,146
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
group 4 medulloblastoma 4 | 1,855
Acquired scoliosis 3 | 281
Cherry red spot of the macula 3 | 7
Cognitive delay 3 | 608
Congenital Epicanthus 3 | 177
Corneal Opacity 3 | 53
Curvature of spine 3 | 282
Frontal bossing 3 | 157
Gait abnormality 3 | 135
Gangliosidosis 3 | 20
Global developmental delay 3 | 608
Hernia, Inguinal 3 | 89
Mental and motor retardation 3 | 608
Nystagmus 3 | 317
Osteochondrodysplasias 3 | 72
Pick disease 3 | 1,894
Sialuria 3 | 9
Vacuolated lymphocytes 3 | 8
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
primary pancreatic ductal adenocarcinoma 3 | 1,109
Amyotrophic lateral sclerosis 2 | 451
Bipolar Disorder 2 | 666
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Cerebral atrophy 2 | 178
Clouding of corneal stroma 2 | 50
Dwarfism 2 | 37
Failure to gain weight 2 | 365
Gingival Hyperplasia 2 | 34
Gingival Hypertrophy 2 | 34
Gingival Overgrowth 2 | 36
Nasal bridge wide 2 | 236
Pediatric failure to thrive 2 | 365
Psychotic Disorders 2 | 151
medulloblastoma 2 | 720
muscle degeneration 2 | 139
posterior fossa group A ependymoma 2 | 468
posterior fossa group B ependymoma 2 | 416
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Digestive Tract 31 | 17,369
Endocrine System 31 | 18,159
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Male tissues 30 | 17,142
Urinary Tract 29 | 16,678
Respiratory system 28 | 16,393

Target Family

Enzyme 30 | 4,145
Transporter 2 | 473

Reactome Pathway

Sialic acid metabolism 32 | 32
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 ST6GALNAC2 Tbio Enzyme -1.74190 55.6 59
Alpha-2,8-sialyltransferase 8B ST8SIA2 Tbio Enzyme -3.21526 1661.4 82
Sialidase-3 NEU3 Tbio Enzyme -2.02704 118.2 35
Alpha-2,8-sialyltransferase 8F ST8SIA6 Tdark Enzyme -0.50778 3.44 74
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase ST6GALNAC4 Tbio Enzyme -0.79236 5.02 74
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST6GALNAC6 Tdark Enzyme -0.47821 3.24 63
Lysosomal protective protein CTSA Tchem Enzyme -3.07101 1162.7 300
N-acylneuraminate-9-phosphatase NANP Tbio Enzyme -2.36784 234.7 207
Sialic acid synthase NANS Tbio Enzyme -1.90302 79.7 128
Sialidase-1 NEU1 Tbio Enzyme -2.07548 116.0 278