Development Level

Tbio 2 | 10,625
Tclin 2 | 602
Tchem 1 | 1,890

Disease

psoriasis 3 | 6,685
Alcohol dependence 2 | 107
Attention deficit hyperactivity disorder 2 | 156
Autistic Disorder 2 | 320
Autoimmune polyendocrine syndrome 2 | 6
Bipolar Disorder 2 | 266
Chordoid glioma 2 | 4
Major Depressive Disorder 2 | 106
Schizophrenia 2 | 503
group 3 medulloblastoma 2 | 2,254
lung carcinoma 2 | 2,844
medulloblastoma, large-cell 2 | 6,234
ATTENTION DEFICIT-HYPERACTIVITY DISORDER, SUSCEPTIBILITY TO, 7 1 | 1
Amyotrophic neuralgia 1 | 13
Anxiety disorder 1 | 22
Aromatic L-amino-acid decarboxylase deficiency 1 | 1
Aromatic amino acid decarboxylase deficiency 1 | 1
Attention deficit-hyperactivity disorder 7 1 | 1
Constipation 1 | 43
DELAYED SLEEP PHASE SYNDROME, SUSCEPTIBILITY TO 1 | 1
Deficiency of aromatic-L-amino-acid decarboxylase 1 | 1
Delayed Sleep Phase Syndrome 1 | 1
Depressive disorder 1 | 48
Diarrhea 1 | 155
Dissociative amnesia 1 | 2
Dystonia 1 | 77
Fever 1 | 34
Hepatolenticular Degeneration 1 | 24
Hyperprolactinemia 1 | 22
Idiopathic scoliosis 1 | 29
Irritable bowel syndrome 1 | 59
Leukemia, Lymphocytic, Acute, L1 1 | 11
Lymphoid leukemia 1 | 69
Mental disorders 1 | 11
Nerve Degeneration 1 | 73
Oppositional defiant disorder 1 | 16
Panic disorder 1 | 55
Parkinson Disease 1 | 105
Parkinson's disease 1 | 364
Parkinsonian Disorders 1 | 23
Parkinsonism 1 | 19
Personality disorder 1 | 25
Pheochromocytoma 1 | 22
Pineoblastoma 1 | 7
Postencephalitic parkinsonism 1 | 12
Ptosis 1 | 42
Pulmonary hypertension 1 | 52
Seasonal affective disorder 1 | 25
Sleep Disorders, Circadian Rhythm 1 | 1
Small intestine neuroendocrine neoplasm 1 | 1
Substance abuse 1 | 55
Sudden infant death syndrome 1 | 34
aldosterone-producing adenoma 1 | 664
colon cancer 1 | 1,475
cutaneous lupus erythematosus 1 | 1,056
esophageal adenocarcinoma 1 | 737
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
lung cancer 1 | 4,473
nephrosclerosis 1 | 329
osteosarcoma 1 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pituitary cancer 1 | 1,972
ulcerative colitis 1 | 2,087

Tissue

Blood and immune system 5 | 17,994
Cardiovascular System 5 | 17,957
Digestive Tract 5 | 18,472
Endocrine System 5 | 18,511
Female tissues 5 | 18,646
Liver and Pancreas 5 | 18,135
Male tissues 5 | 17,968
Nervous System 5 | 18,560
Respiratory system 5 | 17,483
Skin and soft tissues 5 | 18,114
Urinary Tract 5 | 18,443

Target Family

Enzyme 5 | 4,146

Reactome Pathway

Serotonin and melatonin biosyn... 5 | 5
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Acetylserotonin O-methyltransferase ASMT Tbio Enzyme -2.38905 249.9 102
Tryptophan 5-hydroxylase 2 TPH2 Tchem Enzyme -2.42413 295.6 323
Aromatic-L-amino-acid decarboxylase DDC Tclin Enzyme -2.77547 575.1 325
Tryptophan 5-hydroxylase 1 TPH1 Tclin Enzyme -2.90440 740.7 364
Serotonin N-acetyltransferase AANAT Tbio Enzyme -2.24741 176.5 175