Development Level

Tbio 7 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating magnesiu... 1 | 13
edema 1 | 59
increased circulating bilirubi... 1 | 16
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
small adrenal glands 1 | 16
thrombocytopenia 1 | 56

Disease

medulloblastoma, large-cell 5 | 6,241
ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
glioblastoma 4 | 5,792
osteosarcoma 4 | 7,950
psoriasis 4 | 6,694
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
Adenocarcinoma of lung 2 | 142
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cognitive delay 2 | 608
Disease Models, Animal 2 | 155
Down syndrome 2 | 499
Epilepsy 2 | 792
Fetal Growth Retardation 2 | 189
Global developmental delay 2 | 608
Infant, Small for Gestational Age 2 | 176
Infantile onset 2 | 238
Intrauterine retardation 2 | 176
Mental and motor retardation 2 | 608
Multiple myeloma 2 | 1,332
Muscle Hypertonia 2 | 88
Schizophrenia 2 | 1,160
Seizures 2 | 596
Serine deficiency 2 | 9
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
primitive neuroectodermal tumor 2 | 3,035
Acquired metabolic disease 1 | 336
Acquired scoliosis 1 | 281
Alcohol dependence 1 | 107
Alcoholic Intoxication, Chronic 1 | 289
Atopic dermatitis 1 | 952
Auricular malformation 1 | 41
Breast cancer 1 | 3,578
Byzanthine arch palate 1 | 194
Cancer 1 | 2,499
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiovascular system disease 1 | 246
Chronic Lymphocytic Leukemia 1 | 262
Curvature of spine 1 | 282
Ichthyoses 1 | 41
Liver Cirrhosis, Experimental 1 | 769
MYELODYSPLASTIC SYNDROME 1 | 53
Microcephaly 1 | 166
Neu Laxova syndrome 1 | 2
Neu-Laxova syndrome 1 | 2
Neu-Laxova syndrome 1 1 | 2
Osteoporosis 1 | 363
Polycystic ovary syndrome 1 | 360
Postnatal microcephaly 1 | 24
Prenatal onset 1 | 139
Prostatic Neoplasms 1 | 495
Reduced fetal movement 1 | 51
Rheumatoid arthritis 1 | 1,191
Simple ear 1 | 41
Spondylosis 1 | 16
Thrombocytosis 1 | 38
Type 2 diabetes mellitus 1 | 272
Vertical Talus 1 | 25
X-linked cerebral adrenoleukodystrophy 1 | 116
active ulcerative colitis 1 | 764
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
atypical teratoid/rhabdoid tumor 1 | 357
chronic rhinosinusitis 1 | 512
gastric cancer 1 | 459
hepatocellular carcinoma 1 | 547
medulloblastoma 1 | 720
non-small cell lung carcinoma 1 | 317
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
primary Sjogren syndrome 1 | 735
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
substance-related disorder 1 | 162
tuberculosis and treatment for 3 months 1 | 179
ulcerative colitis 1 | 1,819

Tissue

Digestive Tract 8 | 17,369
Endocrine System 8 | 18,159
Female tissues 8 | 17,400
Nervous System 8 | 16,725
Blood and immune system 7 | 16,909
Cardiovascular System 7 | 15,192
Liver and Pancreas 7 | 16,750
Male tissues 7 | 17,142
Respiratory system 7 | 16,393
Skin and soft tissues 7 | 17,230
Urinary Tract 7 | 16,678

Target Family

Non-IDG 5 | 12,091
Enzyme 3 | 4,145

Reactome Pathway

Serine biosynthesis 8 | 8
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine incorporator 5 SERINC5 Tbio Non-IDG -1.50535 34.0 11
Serine incorporator 4 SERINC4 Tdark Non-IDG 0.00000 33
Serine incorporator 3 SERINC3 Tbio Non-IDG -2.44903 264.3 131
Phosphoserine phosphatase PSPH Tbio Enzyme -1.56433 55.8 252
Phosphoserine aminotransferase PSAT1 Tbio Enzyme -2.25926 176.4 136
Serine incorporator 2 SERINC2 Tbio Non-IDG -0.89181 7.54 119
Serine incorporator 1 SERINC1 Tbio Non-IDG -1.50356 29.4 97
Serine racemase SRR Tbio Enzyme -2.65754 451.3 154