Development Level

Tdark 70 | 6,588
Tbio 15 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal limb bud morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased exploration in new e... 1 | 11
decreased heart rate variabili... 1 | 13
embryonic lethality prior to t... 1 | 278
pallor 1 | 34
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 13 | 7,950
interstitial cystitis 12 | 2,312
psoriasis 12 | 6,694
tuberculosis 12 | 2,010
lung adenocarcinoma 11 | 2,716
lung cancer 11 | 4,740
periodontitis 11 | 293
chronic lymphosyte leukemia 9 | 204
ulcerative colitis 9 | 1,819
lung carcinoma 8 | 2,843
mucosa-associated lymphoid tissue lymphoma 8 | 484
non-small cell lung cancer 8 | 2,890
Multiple myeloma 7 | 1,332
diabetes mellitus 7 | 1,728
ovarian cancer 7 | 8,520
pancreatic cancer 7 | 2,398
Breast cancer 6 | 3,578
cutaneous lupus erythematosus 6 | 1,057
primary pancreatic ductal adenocarcinoma 6 | 1,109
Cancer 5 | 2,499
Carcinoma 5 | 11,493
Kidney disease 5 | 430
colon cancer 5 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Atherosclerosis 4 | 291
Chronic obstructive pulmonary disease 4 | 184
Hypertension 4 | 396
Leukemia 4 | 104
Liver disease 4 | 237
Schizophrenia 4 | 1,160
cystic fibrosis and chronic rhinosinusitis 4 | 214
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
medulloblastoma, large-cell 4 | 6,241
non-small cell lung carcinoma 4 | 317
Amebiasis 3 | 21
Anemia 3 | 365
Arthritis 3 | 290
Chemical and Drug Induced Liver Injury 3 | 195
Hepatomegaly 3 | 285
Isolated growth hormone deficiency 3 | 30
Lymphoma 3 | 81
Malaria 3 | 160
Sleeping sickness 3 | 37
Vascular disease 3 | 319
atypical teratoid / rhabdoid tumor 3 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
Amyloidosis 2 | 67
Anemia, Sickle Cell 2 | 8
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autoimmune Diseases 2 | 67
Autosomal recessive predisposition 2 | 1,442
Depressive disorder 2 | 409
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Duchenne muscular dystrophy 2 | 601
Glucosephosphate dehydrogenase deficiency 2 | 15
HIV Infections 2 | 102
Heart disease 2 | 306
Hematuria 2 | 36
Hemochromatosis 2 | 54
Hemoglobin low 2 | 124
Hypertensive disease 2 | 292
IGA Glomerulonephritis 2 | 50
Kidney cancer 2 | 2,613
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Obesity 2 | 678
Splenomegaly 2 | 190
Thalassemia 2 | 53
Unipolar Depression 2 | 250
Waldenstrons macroglobulinemia 2 | 765
X-linked agammaglobulinemia 2 | 7
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
glioblastoma 2 | 5,792
group 3 medulloblastoma 2 | 4,104
juvenile dermatomyositis 2 | 1,187
primary Sjogren syndrome 2 | 735
Abnormality of the spleen 1 | 13
Autoimmune hemolytic anemia 1 | 31
Behcet Syndrome 1 | 21
Common Migraine 1 | 7
Complications of Diabetes Mellitus 1 | 5
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Histiocytosis 1 | 12
Iron deficiency anemia 1 | 12
Methemoglobinemia 1 | 17
Migraine without Aura 1 | 11
Thrombotic thrombocytopenic purpura 1 | 14

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 85 | 12,091

Reactome Pathway

Scavenging of heme from plasma 85 | 85
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.93036 825.2 985
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-16 IGKV1-16 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-17 IGKV1-17 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-39 IGKV1-39 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-33 IGKV1-33 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1D-33 IGKV1D-33 Tdark Non-IDG 0.00000 0
Immunoglobulin J chain JCHAIN Tbio Non-IDG -2.58576 355.8 218
Protein AMBP AMBP Tbio Non-IDG -2.61031 420.1 396