Development Level

Tbio 33 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588
Tclin 2 | 613

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal heart morphology 2 | 162
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal seminal vesicle morph... 1 | 114
decreased circulating chloride... 1 | 30
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
sclerocornea 1 | 2

Disease

Carcinoma 34 | 11,493
lung cancer 29 | 4,740
group 3 medulloblastoma 28 | 4,104
ovarian cancer 27 | 8,520
osteosarcoma 24 | 7,950
medulloblastoma, large-cell 22 | 6,241
atypical teratoid / rhabdoid tumor 19 | 5,112
psoriasis 19 | 6,694
glioblastoma 18 | 5,792
non-small cell lung cancer 17 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
primitive neuroectodermal tumor 15 | 3,035
Breast cancer 14 | 3,578
Cancer 13 | 2,499
adult high grade glioma 13 | 3,801
Kidney cancer 12 | 2,613
dermatomyositis 11 | 966
invasive ductal carcinoma 11 | 2,951
ependymoma 10 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
oligodendroglioma 10 | 2,850
Waldenstrons macroglobulinemia 9 | 765
malignant mesothelioma 9 | 3,232
Multiple myeloma 8 | 1,332
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
colon cancer 8 | 1,478
Atopic dermatitis 7 | 952
acute quadriplegic myopathy 7 | 1,158
adrenocortical carcinoma 7 | 1,428
lung adenocarcinoma 7 | 2,716
Pick disease 6 | 1,894
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,058
Astrocytoma, Pilocytic 5 | 3,081
Endometriosis 5 | 540
astrocytoma 5 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
tuberculosis 5 | 2,010
pancreatic cancer 4 | 2,398
pediatric high grade glioma 4 | 1,064
ulcerative colitis 4 | 1,819
Amyotrophic lateral sclerosis 3 | 451
Autosomal recessive predisposition 3 | 1,442
Breast Neoplasms 3 | 445
Leukemia 3 | 104
Mammary Neoplasms 3 | 425
interstitial cystitis 3 | 2,312
interstitial lung disease 3 | 298
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
subependymal giant cell astrocytoma 3 | 2,287
Adenocarcinoma 2 | 122
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Deglutition Disorders 2 | 132
Galloway-Mowat syndrome 2 | 15
Leukemia, Myelocytic, Acute 2 | 120
Lung Neoplasms 2 | 232
Malignant tumor of ovary 2 | 25
Mammary Neoplasms, Experimental 2 | 154
Melanoma 2 | 711
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 2 | 4
Nephrotic syndrome, idiopathic, steroid-resistant 2 | 4
Neuroblastoma 2 | 80
Neurodegenerative disease 2 | 414
Neutropenia 2 | 72
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Rheumatoid arthritis 2 | 1,191
Stomach Neoplasms 2 | 300
Uterine Cervical Neoplasm 2 | 25
Uterine Cervical Neoplasms 2 | 26
Vaccinia 2 | 36
acute myeloid leukemia 2 | 783
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis and chronic rhinosinusitis 2 | 214
esophageal adenocarcinoma 2 | 737
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074
Acute gonococcal cervicitis 1 | 1
Acute osteomyelitis 1 | 1
Chancroid 1 | 8
Citrobacter Urinary Tract Infection 1 | 1
Complicated Bacteroides Peritonitis 1 | 1
Cystitis 1 | 15
Enterobacter Osteomyelitis 1 | 1
EnterobacterJoint Infection 1 | 1
Enterococcus Urinary Tract Infection 1 | 1
Escherichia coli urinary tract infection 1 | 1
Haemophilus influenzae pneumonia 1 | 2
Infectious diarrheal disease 1 | 1
Klebsiella Nosocomial Pneumonia 1 | 1
Nosocomial Pneumonia due to Haemophilus Influenzae 1 | 1
Serratia Joint Infection 1 | 1
Skin and Skin Structure Proteus Infection 1 | 1

Tissue

Blood and immune system 43 | 16,909
Cardiovascular System 43 | 15,192
Digestive Tract 43 | 17,369
Endocrine System 43 | 18,159
Female tissues 43 | 17,400
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Respiratory system 43 | 16,393
Skin and soft tissues 43 | 17,230
Urinary Tract 43 | 16,678

Target Family

Non-IDG 34 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400

Reactome Pathway

SUMOylation of DNA replication... 44 | 44
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
E3 SUMO-protein ligase PIAS3 PIAS3 Tbio Transcription Factor -1.74449 53.4 174
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.61701 4015.4 248
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.88264 723.0 847
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -1.04073 10.5 78
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254