Development Level

Tchem 3 | 1,598
Tbio 1 | 11,445

IMPC Phenotype

absent testes 1 | 6

Disease

Cancer 4 | 2,499
Myocardial Reperfusion Injury 4 | 37
Carcinoma 3 | 11,493
Brain Ischemia 2 | 110
Prostatic Neoplasms 2 | 495
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
medulloblastoma, large-cell 2 | 6,241
AMYOTROPHIC LATERAL SCLEROSIS 1 1 | 49
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Anemia 1 | 365
Autosomal dominant nonsyndromic deafness 64 1 | 1
Barrett's esophagus 1 | 182
Breast Neoplasms 1 | 445
Breast cancer 1 | 3,578
Cellular immunodeficiency 1 | 17
Congenital myasthenic syndrome 13 1 | 2
DEAFNESS, AUTOSOMAL DOMINANT 64 1 | 1
Decreased antibody level in blood 1 | 35
Decreased platelet count 1 | 111
Edema 1 | 81
Encephalitis 1 | 64
Esophageal Neoplasms 1 | 69
Fulminant hepatitis 1 | 2
Hemoglobin low 1 | 124
Hemophagocytic lymphohistiocytosis 1 | 30
Hepatic encephalopathy 1 | 27
Hepatomegaly 1 | 285
Huntington Disease 1 | 13
Hypertrophic cardiomyopathy 1 1 | 2
Hypogammaglobulinemia 1 | 35
IgG Deficiency 1 | 22
Immunologic Deficiency Syndromes 1 | 113
Increased IgM levels 1 | 16
Ischemic Attack, Transient 1 | 10
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liver Cirrhosis, Experimental 1 | 769
Lymphadenopathy 1 | 62
Lymphoma 1 | 81
Lymphoproliferative Disorders 1 | 6
Lymphoproliferative Syndrome, X-Linked, 2 1 | 1
Lymphoproliferative syndrome 1 | 58
Lymphoproliferative syndrome 1, X-linked 1 | 3
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Experimental 1 | 154
Meningitis 1 | 67
Nervous System Diseases 1 | 53
Nonsyndromic deafness 1 | 142
Ovarian Neoplasms 1 | 102
Pancytopenia 1 | 45
Parkinson's disease 1 | 392
Peripheral Nervous System Diseases 1 | 52
Peripheral Neuropathy 1 | 134
Reduced natural killer cell activity 1 | 3
Retinal Detachment 1 | 51
Splenomegaly 1 | 190
Thrombocytopenia 1 | 197
Toxic encephalopathy 1 | 141
Transient Ischemic Attack 1 | 10
Type 1 diabetes mellitus 17 1 | 2
Vascular disease 1 | 319
Vitiligo 1 | 73
X- linked recessive 1 | 110
X-Linked Lymphoproliferative Disorder 1 | 2
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
colon cancer 1 | 1,478
esophageal adenocarcinoma 1 | 737
fascioscapulohumeral muscular dystrophy 1 | 100
group 3 medulloblastoma 1 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
lung carcinoma 1 | 2,843
nervous system disorder 1 | 53
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
ovarian neoplasm 1 | 99
pediatric high grade glioma 1 | 1,064
pharyngitis recurrent 1 | 4
primary pancreatic ductal adenocarcinoma 1 | 1,109
psoriasis 1 | 6,694
tuberculosis 1 | 2,010

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 3 | 4,145
Non-IDG 1 | 12,091

Reactome Pathway

SMAC-mediated dissociation of ... 4 | 4
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caspase-9 CASP9 Tchem Enzyme -3.44725 2332.0 1313
Caspase-7 CASP7 Tchem Enzyme -2.69052 418.1 800
E3 ubiquitin-protein ligase XIAP XIAP Tchem Enzyme -3.13488 1375.8 504
Diablo homolog, mitochondrial DIABLO Tbio Non-IDG -2.94553 955.2 520