Development Level

Tbio 7 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 2 | 979
increased mean corpuscular hem... 1 | 96

Disease

Carcinoma 5 | 11,493
group 3 medulloblastoma 5 | 4,104
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
glioblastoma 3 | 5,792
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
Breast cancer 2 | 3,578
Epilepsy 2 | 792
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
ependymoma 2 | 4,679
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
osteosarcoma 2 | 7,950
11 pairs of ribs 1 | 7
Absence of eyebrows 1 | 31
Absent auditory canals 1 | 23
Absent external auditory canals 1 | 23
Acquired scoliosis 1 | 281
Adenocarcinoma of lung 1 | 142
Alopecia 1 | 115
Animal Mammary Neoplasms 1 | 136
Aplasia/Hypoplasia of the eyebrow 1 | 31
Asthenopia 1 | 10
Atresia of the external auditory canal 1 | 23
Atretic auditory canal 1 | 23
Bilateral fifth finger clinodactyly 1 | 110
Byzanthine arch palate 1 | 194
Cavernous hemangioma 1 | 11
Cerebrovascular disease 1 | 238
Chronic obstructive pulmonary disease 1 | 184
Conductive hearing loss 1 | 123
Congenital Epicanthus 1 | 177
Curvature of little finger 1 | 110
Curvature of spine 1 | 282
Cystic kidney 1 | 30
Death in early childhood 1 | 82
Death in infancy 1 | 82
Dental abnormalities 1 | 60
Dentin sensitivity 1 | 14
Disease Models, Animal 1 | 155
Disease Progression 1 | 136
Enamel erosion 1 | 19
Flexion contracture - elbow 1 | 32
Glossoptosis 1 | 10
HIV Infections 1 | 102
Hemangioma 1 | 69
Hip Dislocation, Congenital 1 | 48
Hyperkyphosis 1 | 111
Hypernasal voice 1 | 39
Hypotrichosis 1 | 47
Hypotrichosis of the scalp 1 | 6
Hypotrichosis simplex 1 | 7
Hypotrophic malar bone 1 | 129
Kyphosis deformity of spine 1 | 114
Long philtrum 1 | 137
Malar flattening 1 | 129
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Meningioma 1 | 41
Mixed connective tissue disease 1 | 16
Muscular atrophy 1 | 71
Nasal voice 1 | 39
Partial to total absence of eyelashes 1 | 7
Polyhydramnios 1 | 108
Porencephaly 1 | 20
Posterior displacement of the tongue 1 | 10
Posteriorly rotated ear 1 | 61
Postnatal growth retardation 1 | 57
Renal cyst 1 | 30
Respiratory Distress Syndrome 1 | 15
Short upper arms 1 | 16
Sparse body hair 1 | 32
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Sparse or absent eyebrows 1 | 31
Sparse to absent eyelashes 1 | 7
Sparse/absent eyebrows 1 | 31
Stomach Neoplasms 1 | 300
Systemic lupus erythematosus 1 | 194
Thoracic hypoplasia 1 | 14
Tooth Abnormalities 1 | 69
Tracheomalacia 1 | 22
Ventricular Septal Defects 1 | 119
adrenocortical carcinoma 1 | 1,428
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
hepatocellular carcinoma 1 | 547
lung adenocarcinoma 1 | 2,716
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 8 | 12,091
Transcription Factor 1 | 1,400

Reactome Pathway

SLBP independent Processing of... 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 473 ZNF473 Tbio Transcription Factor -1.11630 12.6 101
U7 snRNA-associated Sm-like protein LSm11 LSM11 Tbio Non-IDG -0.88176 8.09 49
Small nuclear ribonucleoprotein G SNRPG Tdark Non-IDG 0.12 1.33 104
Small nuclear ribonucleoprotein Sm D3 SNRPD3 Tbio Non-IDG -1.64561 38.0 165
Nuclear cap-binding protein subunit 1 NCBP1 Tbio Non-IDG -2.34134 207.7 172
Nuclear cap-binding protein subunit 2 NCBP2 Tbio Non-IDG -1.45099 24.2 110
Small nuclear ribonucleoprotein F SNRPF Tdark Non-IDG -0.37512 2.26 77
Small nuclear ribonucleoprotein-associated proteins B and B' SNRPB Tbio Non-IDG -2.56036 349.6 117
Small nuclear ribonucleoprotein E SNRPE Tbio Non-IDG -2.77886 589.3 234