Development Level

Tbio 21 | 11,445
Tdark 9 | 6,588
Tchem 2 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal heart left ventricle ... 1 | 16
increased circulating chloride... 1 | 41

Disease

ovarian cancer 15 | 8,520
psoriasis 14 | 6,694
Breast cancer 12 | 3,578
Carcinoma 12 | 11,493
lung cancer 12 | 4,740
invasive ductal carcinoma 9 | 2,951
lung adenocarcinoma 9 | 2,716
osteosarcoma 9 | 7,950
Cancer 8 | 2,499
ductal carcinoma in situ 8 | 1,745
breast carcinoma 7 | 1,638
malignant mesothelioma 7 | 3,232
non-small cell lung cancer 7 | 2,890
Multiple myeloma 6 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic cancer 5 | 2,398
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
Schizophrenia 4 | 1,160
cutaneous lupus erythematosus 4 | 1,057
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
non-small cell lung carcinoma 4 | 317
Cleft Palate 3 | 271
Connective tissue disease 3 | 62
Lupus erythematosus 3 | 57
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
Bipolar Disorder 2 | 666
Endometriosis 2 | 540
Huntington's disease 2 | 76
Retinitis pigmentosa 20 2 | 5
Thyroiditis 2 | 29
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
gastric cancer 2 | 459
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
Ankylosing spondylitis 1 | 140
Autosomal dominant cerebellar ataxia 1 | 33
Brain disease 1 | 96
Broad-based gait 1 | 19
Confusion 1 | 21
Deglutition Disorders 1 | 132
Diabetes Mellitus, Experimental 1 | 108
Diffuse cerebral atrophy 1 | 8
Esophageal Squamous Cell Carcinoma 1 | 77
Fanconi anemia 1 | 56
Fatty Liver 1 | 70
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Galactosemia 1 | 19
Glucose Intolerance 1 | 19
HIV Infections 1 | 102
Hallucinations 1 | 34
Hallucinations, Sensory 1 | 33
Hereditary spherocytosis type 1 1 | 23
Hyperglycemia 1 | 137
Hypertrophy 1 | 17
Impaired glucose tolerance 1 | 28
Insulin Resistance 1 | 72
Lynch syndrome 1 | 35
Metabolic syndrome X 1 | 52
Muscle Rigidity 1 | 49
Myoclonus 1 | 74
Neoplasm Recurrence, Local 1 | 37
Nerve Degeneration 1 | 121
Neurodegeneration with brain iron accumulation 3 1 | 8
Neurodegenerative Disorders 1 | 79
Nijmegen breakage syndrome 1 | 24
Non-alcoholic Fatty Liver Disease 1 | 42
PARKINSON DISEASE, LATE-ONSET 1 | 20
Paralysed 1 | 42
Paralysis 1 | 9
Parkinsonian Disorders 1 | 56
Primary ciliary dyskinesia 1 | 76
Romberg's sign positive 1 | 4
Skin Diseases 1 | 71
Spinocerebellar ataxia type 17 1 | 7
Spinocerebellar ataxia type 2 1 | 23
Squamous cell carcinoma of esophagus 1 | 77
Streptococcal pneumonia 1 | 6
Systemic scleroderma 1 | 60
Testicular cancer 1 | 25
Vaccinia 1 | 36
chorea-acanthocytosis 1 | 12
inflammatory breast cancer 1 | 286

Tissue

Endocrine System 32 | 18,159
Blood and immune system 31 | 16,909
Cardiovascular System 31 | 15,192
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Liver and Pancreas 31 | 16,750
Male tissues 31 | 17,142
Nervous System 31 | 16,725
Respiratory system 31 | 16,393
Skin and soft tissues 31 | 17,230
Urinary Tract 31 | 16,678

Target Family

Non-IDG 25 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242

Reactome Pathway

SIRT1 negatively regulates rRN... 32 | 32
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2B type 1-N HIST1H2BN Tbio Non-IDG -1.51422 30.2 60
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 48
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.27041 18.5 133
Histone H2A.J H2AFJ Tdark Non-IDG -0.00172 0.83 99
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 16
Histone H2B type 1-M HIST1H2BM Tdark Non-IDG 0.17 0.33 21
Histone H2B type 1-C/E/F/G/I HIST1H2BC Tbio Non-IDG -1.38165 22.7 117
Histone H2A.V H2AFV Tdark Non-IDG -1.18642 15.1 40
Histone H2B type F-S H2BFS Tbio Non-IDG -0.50219 4.04 68
TATA box-binding protein-associated factor RNA polymerase I subunit A TAF1A Tbio Enzyme -0.84154 6.46 161